Updated on 2019/05/24

写真a

 
HOSHIBA Takashi
 
Title
Associate Professor(Moving Out or Retirement)
Date of Birth
1979
Contact information
メールアドレス

Research Areas

  • Nanotechnology/Materials / Bio chemistry

  • Life Science / Cell biology

  • Life Science / Biomedical engineering

Graduating School

  • Tokyo Institute of Technology, Faculty of Life Science and Engineering

    2002.03, Graduated

Graduate School

  • Tokyo Institute of Technology, Graduate School, Division of Life Science and Engineering

    Doctor's Course, 2007.03, Completed

External Career

  • , Special researcher of the Japan Society for the Promotion of Science, 2009.04 - 2011.07

 

Research Career

  • Evaluation of hepatocyte functions on the substrate coated with polymer carrying various sugar chains, 2001.04 - 2002.11

    Hepatocytes, sugar-carrying polymer, biomaterials

  • Hepatocyte functions on in vitro basement membrane model formed by cultured cells, 2002.11 - 2004.03

    Hepatocyte, decellularization, basement membrane

  • The analysis of survival mechanism of hepatocytes cultured on various biomaterials, 2004.04 - 2007.03

  • The effects of extracellular matrix proteins deposited at biomaterial interface on hepatocyte functions, 2004.07 - 2007.03

  • The effects of extracellular matrix derived from various cells on the functions of cultured cells, 2007.04 - 2008.05

  • Suppression of dedifferentiation during the subculture of chondrocyte using decellularized matrices, 2007.09 - 2011.05

  • The effects of nuclear deformation of chondrocytes during the subculture on chondrocyte functions, 2008.01 - 2008.06

  • Development of tissue-development-mimicking matrices using decellularization technique, 2008.05 -

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Papers

  • Cultured cell-derived extracellular matrix scaffolds for tissue engineering., Biomaterials, 32 9658-9666, 2011.12

    H. Lu, T. Hoshiba, N. Kawazoe, I. Koda, M. Song, G. Chen

    Multiple Authorship (Including Foreigners)

  • Mechanism of Regulation of PPARG Expression of Mesenchymal Stem Cells by Osteogenesis-Mimicking Extracellular Matrices, Bioscience, Biotechnology, and Biochemistry, 75(11) 2099-2104, 2011.11

    Takashi Hoshiba, Naoki Kawazoe, and Guoping Chen

    Multiple Authorship (Including Foreigners)

  • Regulation of mesenchymal stem cell differentiation using stepwise tissue development-mimicking matrices, Igaku no ayumi, 238(13) 1196-1200, 2011.09

    Guoping Chen, Takashi Hoshiba

    Multiple Authorship (Only Japanese)

  • Effects of Extracellular Matrices Derived from Different Cell Sources on Chondrocyte Functions., Biotechnology Progress, 2011.05

    T. Hoshiba, H. Lu, T. Yamada, N. Kawazoe, T. Tateishi, G. Chen.

    Multiple Authorship (Including Foreigners)

  • Autologous extracellular matrix scaffolds for tissue engineering., Biomaterials, 2011.04

    H. Lu, T. Hoshiba, N. Kawazoe, G. Chen

    Multiple Authorship (Including Foreigners)

  • Design of artificial extracellular matrices for tissue engineering, Progress in Polymer Science, 2011.02

    B.-S. Kim, I.-K. Park, T. Hoshiba, H.-L. Jiang, Y.-J. Choi, T. Akaike, C.S. Cho

    Multiple Authorship (Including Foreigners)

  • Decellularized matrices for tissue engineering, Expert Opinion on Biological Therapy, 2010.12

    T. Hoshiba, H. Lu, N. Kawazoe, G. Chen

    Multiple Authorship (Including Foreigners)

  • Development of extracellular matrices mimicking stepwise adipogenesis of mesenchymal stem cells., Advanced Materials, 2010.07

    T. Hoshiba, N. Kawazoe, T. Tateishi, G. Chen

    Multiple Authorship (Including Foreigners)

  • Society for Biomateials 2010 Annual Meeting & Exposition, バイオマテリアル-生体材料-, 2010.07

    干場隆志

    Single Author

  • Osteogenic differentiation and immune response of human bone marrow-derived mesenchymal stem cells on injectable calcium silicate-based bone grafts., Tissue Engineering Part A, 2010.07

    S.J. Ding, M. Y. Shie, T. Hoshiba, N. Kawazoe, G. Chen, H.C. Chanag

    Multiple Authorship (Including Foreigners)

  • Application of Recombinant Fusion Proteins for Tissue Engineering, Annals of Biomedical Engineering, 2010.03

    M. Nagaoka, H.-L. Jiang, T. Hoshiba, T. Akaike, C.S. Cho

    Multiple Authorship (Including Foreigners)

  • Development of stepwise osteogenesis-mimicking matrices for the regulation of mesenchymal stem cell functions., Journal of Biological Chemistry, 2009.11

    T. Hoshiba, N. Kawazoe, T. Tateishi, G. Chen.

    Multiple Authorship (Including Foreigners)

  • Osteogenic Differentiation of Human Mesenchymal Stem Cells on Chargeable Polymer-Modified Surfaces., Journal of Biomedical Materials Research, 2008.12

    L. Guo, N. Kawazoe, T. Hoshiba, T. Tateishi, G. Chen, X. Zhang

    Multiple Authorship (Including Foreigners)

  • Nuclear deformation and expression change of cartilaginous genes during in vitro expansion of chondrocytes., Biochemical and Biophysical Research Communications, 2008.10

    T. Hoshiba, T. Yamada, H. Lu, N. Kawazoe, T. Tateishi, G. Chen

    Multiple Authorship (Including Foreigners)

  • Different regulation of hepatocyte behaviors between natural extracellular matrices and synthetic extracellular matrices by HGF., Journal of Biomedical Materials Research, 2008.08

    T. Hoshiba, M. Wakejima, C.-S. Cho, G. Shiota, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Regulation of hepatocyte behaviors by galactose-carrying polymers through receptor-mediated mechanism, Reactive and Functional Polymers, 2007.11

    C. S. Cho, T. Hoshiba, I. Harada, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Hepatocytes maintain their function on basement membrane formed by epithelial cells, Biochemical and Biophysical Research Communications, 2007.07

    T. Hoshiba, K. Mochitate, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Effective delivery with enhanced translational activity synergistically accelerates mRNA-based transfection, Biochemical and Biophysical Research Communications, 2007.06

    F.T. Zohra, E.H. Chowdhury, S. Tada, T. Hoshiba, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling., Biomaterials, 2007.02

    T. Hoshiba, H. Nagahara, C. S. Cho, Y. Tagawa, and T. Akaike.

    Multiple Authorship (Including Foreigners)

  • The effect of natural extracellular matrix deposited on synthetic polymers on cultured primary hepatocytes., Biomaterials, 2006.09

    T. Hoshiba, C.S. Cho, A. Murakawa, Y. Okahata, T. Akaike.

    Multiple Authorship (Including Foreigners)

  • Galactose-carrying polymers as extracellular matrices for liver tissue engineering, Biomaterials, 2006.02

    C.S. Cho, S.J. Seo, I.K. Park, S.H. Kim, T.H. Kim, T. Hoshiba, I Harada, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Role of E-cadherin molecules in spheroid formation of hepatocytes adhered on galactose-carrying polymer as an artificial asialoglycoprotein model., Biotechnology Letters, 2005.08

    R. Takei, D. Suzuki, T Hoshiba, M. Nagaoka, S.J. Seo, C.S. Cho, T. Akaike

    Multiple Authorship (Including Foreigners)

  • High-efficiency gene delivery for expression in mammalian cells by nanoprecipitates of Ca-Mg phosphate, Gene, 2004.10

    E.H. Chowdhury, M. Kunou, M. Nagaoka, A.K. Kundu, T. Hoshiba, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Hepatocyte behavior on synthetic glycopolymer matrix: inhibitory effect of receptor-ligand binding on hepatocyte spreading., Biomaterials, 2004.05

    S.-H. Kim, T. Hoshiba, T. Akaike

    Multiple Authorship (Including Foreigners)

  • Effect of carbohydrates attached to polystyrene on hepatocyte morphology on sugar-derivatized polystyrene matrices., Journal of Biomedical Materials Research, 2003.12

    S.-H. Kim, T. Hoshiba, T. Akaike

    Multiple Authorship (Including Foreigners)

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Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Young Scientists(A)，2017.04 - 2020.03