Construction of IgG-Fab(2) bispecific antibody via intein-mediated protein trans-splicing reaction., Scientific reports, 13(1) 15961, 2023.09

Yamada R, Nakahara I, Kumagai I, Asano R, Nakanishi T, Makabe K

Single Author

Heterologous expression of α-1,3-glucanase Agn1p from Schizosaccharomyces pombe, and efficient production of nigero-oligosaccharides by enzymatic hydrolysis from solubilized α-1,3;1,6-glucan, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 87(10) 1219-1228, 2023.09

Horaguchi, Y; Takahashi, M; Takamatsu, K; Konno, H; Makabe, K; Yano, S

Single Author

Grafting a short chameleon sequence from αB crystallin into a β-sheet scaffold protein, Proteins, 2019.01

Yuki Hori, Hideki Fujiwara, Wataru Fujiwara, Koki Makabe

Multiple Authorship (Including Foreigners)

Design, synthesis and evaluation of curcumin-based fluorescent probes to detect Aβ fibrils, Bioorganic & Medicinal Chemistry Letters, 28(22) 3520-3525, 2018.10

Sato T, Hotsumi M, Makabe K, Konno H

Multiple Authorship (Including Foreigners)

Impact in stability during sequential CDR grafting to construct camelid VHH antibodies against zinc oxide and gold, J Biochem., 164(1) 21-25, 2018.07

3. Saito R, Saito Y, Nakazawa H, Hattori T, Kumagai I, Umetsu M, Makabe K

Multiple Authorship (Including Foreigners)

Structural considerations for functional anti-EGFR × anti-CD3 bispecific diabodies in light of domain order and binding affinity, Oncotarget, 164(1) 13884-13893, 2018.02

4. Asano R, Nagai K, Makabe K, Takahashi K, Kumagai T, Kawaguchi H, Ogata H, Arai K, Umetsu M and Kumagai I

Multiple Authorship (Including Foreigners)

Formation of the chaperonin complex studied by 2D NMR spectroscopy, PLoS One, 12(10) e0187022, 2017.10

Takenaka T, Nakamura T, Yanaka S, Yagi-Utsumi M, Chandak MS, Takahashi K, Paul S, Makabe K, Arai M, Kato K, Kuwajima K.

Multiple Authorship (Including Foreigners)

Role of Cys73 in the thermostability of farnesyl diphosphate synthase from Geobacillus stearothermophilus, 3 Biotech, 7 236, 2017

1. Petrus Yesaya Samori, Koki Makabe, Norimasa Ohya, Bunpei Hatano, Satoshi Murakami, Tatsuro Kijima

Multiple Authorship (Including Foreigners)

Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing., Protein Engineering, Design & Selection, 2016.11

Shibuya Y, Haga N, Asano R, Nakazawa H, Hattori T, Takeda D, Sugiyama A, Kurotani R, Kumagai I, Umetsu M, Makabe K

Multiple Authorship (Including Foreigners)

Aromatic cluster mutations produce focal modulations of β-sheet structure, Protein Science, 24 841-849, 2015.05

Biancalana M, Makabe K, Yan S and Koide S

Multiple Authorship (Including Foreigners)

Zinc ion-binding activity of an anti-ZnO VHH antibody, 4F2, Chem. Lett., 2015

1. Ryosuke Sasaki, Soichiro Kitazawa, Ryo Kitahara, Hikaru Nakazawa, Yoshikazu Tanaka, Izumi Kumagai, Mitsuo Umetsu, Koki Makabe

Multiple Authorship (Including Foreigners)

Dissection of the ATP-dependent conformational change cycle of a group II chaperonin., J Mol Biol., 2014

Nakagawa A, Moriya K, Arita M, Yamamoto Y, Kitamura K, Ishiguro N, Kanzaki T, Oka T, Makabe K, Kuwajima K, Yohda M.

Multiple Authorship (Including Foreigners)

Structural insights into the stability perturbations induced by N-terminal variation in human and goat α-lactalbumin., Protein Eng Des Sel., 2013.02

Makabe K, Nakamura T, Kuwajima K.

Multiple Authorship (Including Foreigners)

Native-state heterogeneity of β(2)-microglobulin as revealed by kinetic folding and real-time NMR experiments., J Mol Biol., 2013.01

Mukaiyama A, Nakamura T, Makabe K, Maki K, Goto Y, Kuwajima K.

Multiple Authorship (Including Foreigners)

The molten globule of β(2)-microglobulin accumulated at pH 4 and its role in protein folding., J Mol Biol. , 2013.01

Mukaiyama A, Nakamura T, Makabe K, Maki K, Goto Y, Kuwajima K.

Multiple Authorship (Including Foreigners)

The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and non-substrate tRNA via an induced-fit process., J Biol Chem. , 2013

Ochi A, Makabe K, Yamagami R, Hirata A, Sakaguchi R, Hou YM, Watanabe K, Nureki O, Kuwajima K, Hori H.

Multiple Authorship (Including Foreigners)

ATP dependent rotational motion of group II chaperonin observed by X-ray single molecule tracking., PLoS One , 2013

Sekiguchi H, Nakagawa A, Moriya K, Makabe K, Ichiyanagi K, Nozawa S, Sato T, Adachi S, Kuwajima K, Yohda M, Sasaki YC.

Multiple Authorship (Including Foreigners)

NMR characterization of the interaction of GroEL with amyloid β as a model ligand., FEBS Lett. , 2013

Yagi-Utsumi M, Kunihara T, Nakamura T, Uekusa Y, Makabe K, Kuwajima K, Kato K.

Multiple Authorship (Including Foreigners)

The H/D-exchange Kinetics of the Escherichia coli Co-chaperonin GroES Studied by 2D-NMR and DMSO-Quenched Exchange Methods., J Mol Biol., 2013

Chandak MS, Nakamura T, Makabe K, Takenaka T, Mukaiyama A, Chaudhuri TK, Kato K, Kuwajima K.

Multiple Authorship (Including Foreigners)

Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes., J Biol Chem., 2013

Nakamura T, Aizawa T, Kariya R, Okada S, Demura M, Kawano K, Makabe K, Kuwajima K.

Multiple Authorship (Including Foreigners)

Sequential Four-state Folding/unfolding of Goat a-Lactalbumin and Its N-Terminal Variants, Proteins, 2012.08

Tomoyori K, Nakamura T, Makabe K (Equal contribution with the 1st author), Maki K, Saeki K, Kuwajima K

Multiple Authorship (Including Foreigners)

Fibrillogenic propensity of the GroEL apical domain: A Janus-faced minichaperone, FEBS Letters, 2012.04

Chen J, Yagi H, Sormanni P, Vendruscolo M, Makabe K, Nakamura T, Goto Y, Kuwajima K

Multiple Authorship (Including Foreigners)

Dissecting a Bimolecular Process of MgATP2- Binding to the Chaperonin GroEL, J Mol Biol, 2011.07

Chen J, Makabe K, Nakamura T, Inobe T, Kuwajima K

Multiple Authorship (Including Foreigners)

Different Folding Pathways Taken by Highly Homologous Proteins, Goat alpha-Lactalbumin and Canine Milk Lysozyme, J Mol Biol, 2010.03

Nakamura T, Makabe K, Tomoyori K, Maki K, Mukaiyama A, Kuwajima K

Multiple Authorship (Including Foreigners)

Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes., J Biol Chem, 2010.03

Ochi A, Makabe K, Kuwajima K, Hori H

Multiple Authorship (Including Foreigners)

Minimalist design of water-soluble cross-beta architecture, Proc Natl Acad Sci U S A, 2010.02

Biancalana M, Makabe K, Koide S

Multiple Authorship (Including Foreigners)

Structural Basis for Exquisite Specificity of Affinity Clamps, Synthetic Binding Proteins Generated through Directed Domain-interface Evolution, J Mol Biol, 2009.10

Huang J, Makabe K, Biancalana M, Koide A, Koide S

Multiple Authorship (Including Foreigners)

Molecular Mechanism of Thioflavin-T Binding to the Surface of beta-Rich Peptide Self-Assemblies., J Mol Biol, 2009.01

Biancalana M, Makabe K, Koide A, Koide S

Multiple Authorship (Including Foreigners)

The promiscuity of beta-strand pairing allows for rational design of beta-sheet face inversion., J Am Chem Soc, 2008.11

Makabe K, Koide S

Multiple Authorship (Including Foreigners)

Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics., J Mol Biol, 2008.10

Biancalana M, Makabe K (Equal contribution with the 1st author), Koide A, Koide S

Multiple Authorship (Including Foreigners)

Design of protein function leaps by directed domain interface evolution., Proc Natl Acad Sci U S A, 2008.05

Huang J, Koide A, Makabe K, Koide S

Multiple Authorship (Including Foreigners)

High-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold., J Mol Biol, 2008.04

Makabe K, Biancalana M, Yan S, Tereshko V, Gawlak G, Miller-Auer H, Meredith SC, Koide S

Multiple Authorship (Including Foreigners)

Thermodynamic consequences of mutations in Vernier zone residues of a humanized anti-human epidermal growth factor receptor (EGFR) murine antibody, 528., J Biol Chem, 2008.01

Makabe K, Nakanishi T, Tsumoto K, Tanaka Y, Kondo H, Umetsu M, Sone Y, Asano R, Kumagai I

Multiple Authorship (Including Foreigners)

b-Strand flipping and slipping triggered by turn replacement reveal the opportunistic nature of b-strand pairing., J Am Chem Soc, 2007.11

Makabe K, Yan S, Tereshko V, Gawlak G, Koide S

Multiple Authorship (Including Foreigners)

Human CD4+ central and effector memory T cells produce IL-21: effect on cytokine-driven proliferation of CD4+ T cell subsets., Int. Immunol, 2007.10

Onoda T, Rahman M, Nara H, Araki A, Makabe K, Tsumoto K, Kumagai I, Kudo T, Ishii N, Tanaka N, Sugamura K, Hayasaka K, Asao H

Multiple Authorship (Including Foreigners)

High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma. , Cancer Lett, 2007.10

Akamatsu N, Yamada Y, Hasegawa H, Makabe K, Asano R, Kumagai I, Murata K, Imaizumi Y, Tsukasaki K, Tsuruda K, Sugahara K, Atogami S, Yanagihara K, Kamihira S

Multiple Authorship (Including Foreigners)

Hydrophobic Surface Burial Is the Major Stability Determinant of a Flat, Single-layer beta-Sheet. , J Mol Biol, 2007.04

Yan S, Gawlak G, Makabe K, Tereshko V, Koide A, and Koide S

Multiple Authorship (Including Foreigners)

Atomic structures of peptide self-assembly mimics., Proc Natl Acad Sci U S A, 2006.11

Makabe K, McElheny D, Tereshko V, Hilyard A, Gawlak G, Yan S, Koide A and Koide S

Multiple Authorship (Including Foreigners)

Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering., Protein Science, 2006.08

Makabe K, Tereshko V, Gawlak G, Yan S, Koide S

Multiple Authorship (Including Foreigners)

Humanization of the bispecific epidermal growth factor receptor x CD3 diabody and its efficacy as a potential clinical reagent. , Clin Cancer Res, 2006.07

Asano R, Sone Y, Makabe K, Tsumoto K, Hayashi H, Katayose Y, Unno M, Kudo T, Kumagai I

Multiple Authorship (Including Foreigners)

Tumor-directed lymphocyte-activating cytokines: refolding-based preparation of recombinant human interleukin-12 and an antibody variable domain-fused protein by additive-introduced stepwise dialysis. , Biochem Biophys Res Commun, 2005.03

Makabe K, Asano R, Ito T, Tsumoto K, Kudo T, Kumagai I

Multiple Authorship (Including Foreigners)

A highly effective and stable bispecific diabody for cancer immunotherapy: cure of xenografted tumors by bispecific diabody and T-LAK cells. , Cancer Immunol Immunother, 2004.06

Hayashi H, Asano R, Tsumoto K, Katayose Y, Suzuki M, Unno M, Kodama H, Takemura S, Yoshida H, Makabe K, Imai K, Matsuno S, Kumagai I, Kudo T

Multiple Authorship (Including Foreigners)

Efficient construction of a diabody using a refolding system: anti-carcinoembryonic antigen recombinant antibody fragment., J Biochem (Tokyo), 2002.12

Asano R, Kudo T, Nishimura Y, Makabe K, Hayashi H, Suzuki M, Tsumoto K, Kumagai I

Multiple Authorship (Including Foreigners)

Antitumor activity of interleukin-21 prepared by novel refolding procedure from inclusion bodies expressed in Escherichia coli., FEBS Lett, 2002.09

Asano R, Kudo T, Makabe K (Equal contribution with the 1st author), Tsumoto K, Kumagai I

Multiple Authorship (Including Foreigners)

Grant-in-Aid for challenging Exploratory Research，2014.04 - 2016.03

Grant-in-Aid for Specially Promoted Research，2012.04 - 2017.03

Grant-in-Aid for Young Scientists(B)，2011.04 - 2014.03