Silkworm arylsulfatase in the midgut content is expressed in the silk gland and fed via smearing on the food from the spinneret., Drug discoveries & therapeutics, 16(6) 280-285, 2022.12

Hiroshi Hamamoto, Atsushi Miyashita, Koushirou Kamura, Ryo Horie, Kazuhisa Sekimizu

Single Author

Silkworm arylsulfatase in the midgut content is expressed in the silk gland and fed via smearing on the food from the spinneret(タイトル和訳中), Drug Discoveries & Therapeutics, 16(6) 280-285, 2022.12

Hamamoto Hiroshi, Miyashita Atsushi, Kamura Koushirou, Horie Ryo, Sekimizu Kazuhisa

Single Author

Hybrid assembly using long reads resolves repeats and completes the genome sequence of a laboratory strain of Staphylococcus aureus subsp. aureus RN4220., Heliyon, 8(11) e11376, 2022.11

Suresh Panthee, Hiroshi Hamamoto, Atmika Paudel, Chikara Kaito, Yutaka Suzuki, Kazuhisa Sekimizu

Single Author

Lysocin E Targeting Menaquinone in the Membrane of Mycobacterium tuberculosis Is a Promising Lead Compound for Antituberculosis Drugs., Antimicrobial agents and chemotherapy, 66(9) e0017122, 2022.08

Geberemichal Geberetsadik, Akane Inaizumi, Akihito Nishiyama, Takehiro Yamaguchi, Hiroshi Hamamoto, Suresh Panthee, Aki Tamaru, Manabu Hayatsu, Yusuke Mizutani, Shaban Amina Kaboso, Mariko Hakamata, A...

Single Author

Establishment of a polymerase chain reaction-based method for strain-level management of Enterococcus faecalis EF-2001 using species-specific sequences identified by whole genome sequences., Frontiers in microbiology, 13 959063, 2022

Hiroshi Hamamoto, Akihiko Ano Ogasawara, Masahiro Iwasa, Kazuhisa Sekimizu

Single Author

治療効果のある抗生物質を産生する土壌細菌を選別するための効果的な手法(An efficient method to screen for the soil bacteria producing therapeutically effective antibiotics), The Journal of Antibiotics, 74(12) 850-855, 2021.12

Hamamoto Hiroshi, Panthee Suresh, Hashimoto Kana, Tsuchida Toshio, Sekimizu Kazuhisa

Single Author

Novel Pathogenic Mucorales Identified Using the Silkworm Infection Model., Journal of fungi (Basel, Switzerland), 7(11) , 2021.11

Suresh Panthee, Hiroshi Hamamoto, Yayoi Nishiyama, Atmika Paudel, Kazuhisa Sekimizu

Single Author

Contribution of rsaC, a small non-coding RNA, towards the pathogenicity of Staphylococcus aureus in a mouse systemic infection model, bioRxiv, 2021.10

Suresh Panthee, Hiroshi Hamamoto, Atmika Paudel, Suguru Ohgi, Kazuhisa Sekimizu

Single Author

An efficient method to screen for the soil bacteria producing therapeutically effective antibiotics., The Journal of antibiotics, 74(12) 850-855, 2021.09

Hiroshi Hamamoto, Suresh Panthee, Kana Hashimoto, Toshio Tsuchida, Kazuhisa Sekimizu

Single Author

Transcriptome change in Staphylococcus aureus in infecting mice, preprint on ResearchSquare, 2021.07

Hiroshi Hamamoto, Suresh Panthee, Atmika Paudel, Ohgi Suguru, Yutaka Suzuki, Kazuhisa Sekimizu

Single Author

免疫抑制剤の探索へのカイコモデルの応用(Applying the silkworm model for the search of immunosuppressants), Drug Discoveries & Therapeutics, 15(3) 139-142, 2021.06

Miyashita Atsushi, Hamamoto Hiroshi, Sekimizu Kazuhisa

Single Author

A novel application of bubble-eye strain of Carassius auratus for ex vivo fish immunological studies., Scientific reports, 11(1) 10757, 2021.05

Hiroto Nakajima, Atsushi Miyashita, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

Complete genome sequence and comparative genomic analysis of Enterococcus faecalis EF-2001, a probiotic bacterium., Genomics, 113(3) 1534-1542, 2021.05

Suresh Panthee, Atmika Paudel, Hiroshi Hamamoto, Akihiko Ano Ogasawara, Toshihiro Iwasa, Jochen Blom, Kazuhisa Sekimizu

Single Author

Evaluation of pathogenicity and therapeutic effectiveness of antibiotics using silkworm <i>Nocardia</i> infection model, Drug Discoveries & Therapeutics, 15(2) 73-77, 2021.04

Kazuhiro Mikami, Kazunari Sonobe, Keiko Ishino, Takumi Noda, Mami Kato, Mami Hanao, Hiroshi Hamamoto, Kazuhisa Sekimizu, Mitsuhiro Okazaki

Single Author

カイコNocardia感染モデルを用いた抗菌薬の病原性と治療効果の評価(Evaluaion of pathogenicity and therapeutic effectiveness of antibiotics using silkworm Nocardia infection model), Drug Discoveries & Therapeutics, 15(2) 73-77, 2021.04

Mikami Kazuhiro, Sonobe Kazunari, Ishino Keiko, Noda Takumi, Kato Mami, Hanao Mami, Hamamoto Hiroshi, Sekimizu Kazuhisa, Okazaki Mitsuhiro

Single Author

Development of an in vivo-mimic silkworm infection model with Mycobacterium avium complex., Drug discoveries & therapeutics, 14(6) 287-295, 2021.01

Akiho Yagi, Hiroyuki Yamazaki, Takeshi Terahara, Taehui Yang, Hiroshi Hamamoto, Chiaki Imada, Hiroshi Tomoda, Ryuji Uchida

Single Author

Applying the silkworm model for the search of immunosuppressants., Drug discoveries & therapeutics, 15(3) 139-142, 2021

Atsushi Miyashita, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

Mycobacterium avium complexによるin vivo-mimicカイコ感染モデルの開発(Development of an in vivo-mimic silkworm infection model with Mycobacterium avium complex), Drug Discoveries & Therapeutics, 14(6) 287-295, 2020.12

Yagi Akiho, Yamazaki Hiroyuki, Terahara Takeshi, Yang Taehui, Hamamoto Hiroshi, Imada Chiaki, Tomoda Hiroshi, Uchida Ryuji

Single Author

Serum proteins potentiate therapeutic efficacy of lysocin E against S. aureus, preprint at researchsquare, 2020.11

Hiroshi Hamamoto, Suresh Panthee, Atmika Paudel, Kenichi Ishii, Jyunichiro Yasukawa, Su Jie, Hiroaki Itoh, Kotaro Tokumoto, Masayuki Inoue, Kazuhisa Sekimizu

Single Author

Evaluation of Anti-Mycobacterial Compounds in a Silkworm Infection Model with Mycobacteroides abscessus., Molecules (Basel, Switzerland), 25(21) , 2020.10

Kanji Hosoda, Nobuhiro Koyama, Hiroshi Hamamoto, Akiho Yagi, Ryuji Uchida, Akihiko Kanamoto, Hiroshi Tomoda

Single Author

Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library., Nature communications, 11(1) 4935, 2020.10

Yuri Takada, Hiroaki Itoh, Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu, Masayuki Inoue

Single Author

A simple artificial diet available for research of silkworm disease models., Drug discoveries & therapeutics, 14(4) 177-180, 2020.09

Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

カイコ疾患モデルの研究に利用できる簡単な人工飼料(A simple artificial diet available for research of silkworm disease models), Drug Discoveries & Therapeutics, 14(4) 177-180, 2020.08

Paudel Atmika, Panthee Suresh, Hamamoto Hiroshi, Sekimizu Kazuhisa

Single Author

β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593., Scientific reports, 10(1) 10230, 2020.06

Suresh Panthee, Naoko Kito, Teruo Hayashi, Takeshi Shimizu, Jun Ishikawa, Hiroshi Hamamoto, Hiroyuki Osada, Shunji Takahashi

Single Author

The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity in Staphylococcus aureus., Frontiers in microbiology, 11 2076, 2020

Suresh Panthee, Atmika Paudel, Hiroshi Hamamoto, Anne-Catrin Uhlemann, Kazuhisa Sekimizu

Single Author

Streptococcus pyogenes transcriptome changes in the inflammatory environment of necrotizing fasciitis, Applied and Environmental Microbiology, 85(21) , 2019.11

Yujiro Hirose, Masaya Yamaguchi, Daisuke Okuzaki, Daisuke Motooka, Hiroshi Hamamoto, Tomoki Hanada, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata

Single Author

Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment., Drug discoveries & therapeutics, 13(3) 145-149, 2019.07

Daniel Don Nwibo, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E., Nature communications, 10(1) 2992, 2019.07

Hiroaki Itoh, Kotaro Tokumoto, Takuya Kaji, Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu, Masayuki Inoue

Single Author

Pharmacokinetics of anti-infectious reagents in silkworms., Scientific reports, 9(1) 9451, 2019.07

Hamamoto H, Horie R, Sekimizu K

Single Author

病院以外の環境における多剤耐性コアグラーゼ陰性球菌の分子特性(Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment), Drug Discoveries & Therapeutics, 13(3) 145-149, 2019.06

Don Nwibo Daniel, Panthee Suresh, Hamamoto Hiroshi, Sekimizu Kazuhisa

Single Author

Complete Genome Sequence of Weissella hellenica 0916-4-2 and Its Comparative Genomic Analysis., Frontiers in microbiology, 10 1619, 2019

Suresh Panthee, Atmika Paudel, Jochen Blom, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

GPI0363 inhibits the interaction of RNA polymerase with DNA inStaphylococcus aureus, RSC Advances, 9(65) 37889-37894, 2019

Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu

Single Author

Utilization of Hybrid Assembly Approach to Determine the Genome of an Opportunistic Pathogenic Fungus, Candida albicans TIMM 1768., Genome biology and evolution, 10(8) 2017-2022, 2018.08

Suresh Panthee, Hiroshi Hamamoto, Sanae A Ishijima, Atmika Paudel, Kazuhisa Sekimizu

Single Author

Total Synthesis and Biological Mode of Action of WAP-8294A2: A Menaquinone-Targeting Antibiotic., The Journal of organic chemistry, 83(13) 6924-6935, 2018.07

Hiroaki Itoh, Kotaro Tokumoto, Takuya Kaji, Atmika Paudel, Suresh Panthee, Hiroshi Hamamoto, Kazuhisa Sekimizu, Masayuki Inoue

Single Author

Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis., Cell death & disease, 9(8) 797, 2018.07

Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagay...

Single Author

Pharmacokinetic parameters explain the therapeutic activity of antimicrobial agents in a silkworm infection model., Scientific reports, 8(1) 1578, 2018.01

Atmika Paudel, Suresh Panthee, Makoto Urai, Hiroshi Hamamoto, Tomohiko Ohwada, Kazuhisa Sekimizu

Single Author

[Development of Antibiotics Using Silkworm Bacteria and Fungi Infection Model]., Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 138(7) 895-899, 2018

Hamamoto H, Sekimizu K

Single Author