Updated on 2021/03/23

写真a

 
ISHII Kuniaki
 
Title
Professor(Moving Out or Retirement)

Research Areas

  • Life Science / Pharmacology

Graduate School

  • Tohoku University, Graduate School, Division of Medicine

    Doctor's Course, 1986.03, Completed

 

Papers

  • Azelnidipine treatment reduces the expression of Ca(v)1.2 protein, LIFE SCIENCES, 269 119043, 2021.03

    Nasu Fumiaki, Obara Yutaro, Okamoto Yosuke, Yamaguchi Hiroaki, Kurakami Kazuya, Norota Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • ALOX12 mutation in a family with dominantly inherited bleeding diathesis, JOURNAL OF HUMAN GENETICS, 2021.02

    Mitsui Tetsuo, Makino Satoshi, Tamiya Gen, Sato Hiroko, Kawakami Yuki, Takahashi Yoshitaka, Meguro Toru, Izumino Hiroko, Sudo Yosuke, Norota Ikuo, Ishii Kuniaki, Hayasaka Kiyoshi

    Multiple Authorship (Including Foreigners)

  • Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 141(1) 164-+, 2021.01

    Yamaguchi Kenji, Kanno Emi, Tanno Hiromasa, Sasaki Ayako, Kitai Yuki, Miura Takayuki, Takagi Naoyuki, Shoji Miki, Kasamatsu Jun, Sato Ko, Sato Yuka, Niiyama Momoko, Goto Yuka, Ishii Keiko, Imai Yoshim...

    Multiple Authorship (Including Foreigners)

  • Reply to: MIDN locus structural variants and Parkinson's disease risk, ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 7(4) 604-605, 2020.04

    Obara Yutaro, Sato Hidenori, Nakayama Takahiro, Kato Takeo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • KCNQ1 is internalized by activation of α<sub>1</sub> adrenergic receptors., Biochemical pharmacology, 169 113628, 2019.11

    Kurakami K, Norota I, Nasu F, Ohshima S, Nagasawa Y, Konno Y, Obara Y, Ishii K

    Multiple Authorship (Including Foreigners)

  • Midnolin is a confirmed genetic risk factor for Parkinson's disease., Annals of clinical and translational neurology, 2019.10

    Obara Y, Sato H, Nakayama T, Kato T, Ishii K

    Multiple Authorship (Including Foreigners)

  • Molecular identification of HSPA8 as an accessory protein of a hyperpolarization-activated chloride channel from rat pulmonary vein cardiomyocytes., The Journal of biological chemistry, 2019.09

    Okamoto Y, Nagasawa Y, Obara Y, Ishii K, Takagi D, Ono K

    Multiple Authorship (Including Foreigners)

  • Midnolinは神経突起伸展とparkinユビキチンリガーゼの発現を促進し、パーキンソン病と関連する。, 日本薬理学会年会要旨集, 92(0) 1-O-17, 2019

    小原 祐太郎, 今井 亨, 提箸 尚貴, 佐藤 秀則, 武田 裕司, 加藤 丈夫, 石井 邦明

    Multiple Authorship (Including Foreigners)

  • ERK5 Phosphorylates K(v)4.2 and Inhibits Inactivation of the A-Type Current in PC12 Cells, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(7) , 2018.07

    Kashino Yurina, Obara Yutaro, Okamoto Yosuke, Saneyoshi Takeo, Hayashi Yasunori, Ishii Kuniaki

    Multiple Authorship (Only Japanese)

  • Transcriptome Analysis Reveals That Midnolin Regulates mRNA Expression Levels of Multiple Parkinson's Disease Causative Genes, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 41(1) 20-23, 2018.01

    Obara Yutaro, Ishii Kuniaki

    Multiple Authorship (Only Japanese)

  • Possible anti-proliferative effect of TASK-3 on HEK293 and PANC-1 cells, 日本薬理学会年会要旨集, 2018(0) PO2-10-27, 2018

    Konno Yoshihiro, Sato Makoto, Obara Yutaro, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Midnolin is a novel risk factor for Parkinson's Disease and regulates expression of parkin and other causative genes, 日本薬理学会年会要旨集, 2018(0) PO4-1-131, 2018

    Obara Yutaro, Imai Toru, Sato Hidenori, Takeda Yuji, Kato Takeo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Insulin treatment augments KCNQ1/KCNE1 currents but not KCNQ1 currents, which is associated with an increase in KCNE1 expression, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 493(1) 409-415, 2017.11

    Wu Minghua, Obara Yutaro, Ohshima Shingo, Nagasawa Yoshinobu, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Midnolin is a novel regulator of parkin expression and is associated with Parkinson's Disease, SCIENTIFIC REPORTS, 7(1) 5885, 2017.07

    Obara Yutaro, Imai Toru, Sato Hidenori, Takeda Yuji, Kato Takeo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Licochalcones extracted from Glycyrrhiza inflata inhibit platelet aggregation accompanied by inhibition of COX-1 activity, PLOS ONE, 12(3) e0173628, 2017.03

    Okuda-Tanino Asa, Sugawara Daiki, Tashiro Takumi, Iwashita Masaya, Obara Yutaro, Moriya Takahiro, Tsushima Chisato, Saigusa Daisuke, Tomioka Yoshihisa, Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • Roles of ERK5 in ion channel expression in PC12 cells, JOURNAL OF PHARMACOLOGICAL SCIENCES, 133(3) S217, 2017.03

    Kashino Yurina, Obara Yutaro, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Effects of high glucose on Kv 1.5 and Kir2.1 channels, JOURNAL OF PHARMACOLOGICAL SCIENCES, 130(3) S104, 2016.03

    Jimbu Ryota, Nagasawa Yoshinobu, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Impact of hyperpolarization-activated Cl- current on arrhythmogenecity of rat pulmonary vein cardiomyocytes, JOURNAL OF PHARMACOLOGICAL SCIENCES, 130(3) S77, 2016.03

    Okamoto Yosuke, Ono Kyoichi, Takano Makoto, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells, CELLULAR SIGNALLING, 28(3) 177-189, 2016.03

    Obara Yutaro, Nagasawa Ryusuke, Nemoto Wataru, Pellegrino Michael J., Takahashi Maho, Habecker Beth A., Stork Philip J. S., Ichiyanagi Osamu, Ito Hiromi, Tomita Yoshihiko, Ishii Kuniaki, Nakahata Nori...

    Multiple Authorship (Including Foreigners)

  • Intra-organellar Ca2+ Signaling Imaged Using Genetically Encoded Ca2+ Indicators CEPIA, JOURNAL OF PHARMACOLOGICAL SCIENCES, 130(3) S252, 2016.03

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Azelnidipine reduces surface expression levels of Ca(v)1.2 channel, JOURNAL OF PHARMACOLOGICAL SCIENCES, 128(3) S150, 2015.07

    Nasu Fumiaki, Kurakami Kazuya, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • ERK5 regulates catecholamine biosynthesis and homeostasis in neural cells and human adrenal medullas, JOURNAL OF PHARMACOLOGICAL SCIENCES, 128(3) S141, 2015.07

    Obara Yutaro, Nagasawa Ryusuke, Nemoto Wataru, Pellegrino Michael, Takahashi Maho, Habecker Beth, Stork Philip, Ichiyanagi Osamu, Ito Hiromi, Tomita Yoshihiko, Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA, JOURNAL OF PHARMACOLOGICAL SCIENCES, 128(3) S179, 2015.07

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Phosphorylation of ERK5 on Thr732 Is Associated with ERK5 Nuclear Localization and ERK5-Dependent Transcription, PLOS ONE, 10(2) e0117914, 2015.02

    Honda Takuto, Obara Yutaro, Yamauchi Arata, Couvillon Anthony D., Mason Justin J., Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA, NATURE COMMUNICATIONS, 5 4153, 2014.06

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Insulin suppresses I-Ks (KCNQ1/KCNE1) currents, which require beta-subunit KCNE1, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 466(5) 937-946, 2014.05

    Wu Minghua, Obara Yutaro, Norota Ikuo, Nagasawa Yoshinobu, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • G alpha h/TG2 enhances adenylylcyclase 8 activity in human and rat glioma cells, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 27P, 2014

    Obara Yutaro, Yanagihata Yoshimi, Abe Tomohiro, Dafik Laila, Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • Imaging of Ca2+ dynamics within the endoplasmic reticulum and mitochondria using new GFP-based fluorescent Ca2+ indicators, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 92P, 2014

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Is PIP2 involved in the insulin effect?, CHANNELS, 8(5) 391-392, 2014

    Ishii Kuniaki, Wu Minghua, Obara Yutaro

    Multiple Authorship (Including Foreigners)

  • Possible involvement of PIP2 in KCNQ1/KCNE1 current inhibition by insulin, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 106P, 2014

    Ohshima Shingo, Nagasawa Yoshinobu, Wu Minghua, Ikuo Norota, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • On the mechanism by which receptor activation modulates I-Ks channel - involvement of PIP2 -, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 59P, 2014

    Ishii Kuniaki, Ohsima Shingo, Nagasawa Yoshinobu, Kurakami Kazuya, Norota Ikuo

    Multiple Authorship (Including Foreigners)

  • NGF activates ERK5 in Ras and Rap1-independent manners and promotes neurite outgrowth and catecholamine biosynthesis, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 66P, 2014

    Obara Yutaro, Stork Philip, Habecker Beth, Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • KCNQ1 channel does not form a complex with alpha(1) adrenergic receptor when it is internalized by the receptor activation, JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 195P, 2014

    Kurakami Kazuya, Norota Ikuo, Nagasawa Yoshinobu, Obara Yutaro, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • 神経系におけるERK5の役割について, 日本薬理學雜誌 = Folia pharmacologica Japonica, 141(6) , 2013.06

    小原 祐太郎, 石井 邦明

    Multiple Authorship (Including Foreigners)

  • [Roles of ERK5 in neuronal cells]., Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 141(6) 354, 2013.06

    Obara Y, Ishii K

    Multiple Authorship (Including Foreigners)

  • 多彩な機能を有するG_h/トランスグルタミナーゼ2, 日本薬理學雜誌 = Folia pharmacologica Japonica, 141(4) , 2013.04

    小原 祐太郎, 石井 邦明

    Multiple Authorship (Including Foreigners)

  • [Multiple functions of Gh/transglutaminase 2]., Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 141(4) 225, 2013.04

    Obara Y, Ishii K

    Multiple Authorship (Including Foreigners)

  • Is a Novel SCN3B Mutation Commonly Found in SCN5A-Negative Brugada Syndrome Patients?, CIRCULATION JOURNAL, 77(4) 900-901, 2013.04

    Kurakami Kazuya, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • G alpha(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells, CELLULAR SIGNALLING, 25(3) 589-597, 2013.03

    Obara Yutaro, Yanagihata Yoshimi, Abe Tomohiro, Dafik Laila, Ishii Kuniaki, Nakahata Norimichi

    Multiple Authorship (Including Foreigners)

  • Imaging of Ca2+ dynamics within the endoplasmic reticulum using new fluorescent Ca2+ indicators, JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 191P, 2013

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Internalization of KCNQ1 channel by activation of the alpha(1A) and alpha(1B) adrenergic receptor, JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 97P, 2013

    Kurakami Kazuya, Norota Ikuo, Wu Minghua, Obara Yutaro, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Endocytic Regulation of Voltage-Dependent Potassium Channels in the Heart, JOURNAL OF PHARMACOLOGICAL SCIENCES, 120(4) 264-269, 2012.12

    Ishii Kuniaki, Norota Ikuo, Obara Yutaro

    Multiple Authorship (Including Foreigners)

  • Bidirectional roles of brain 2-arachidonoylglycerol in bombesin-induced activation of central sympatho-adrenomedullary outflow in rats, JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 73P, 2012

    Ino Daisuke, Kanemaru Kazunori, Okubo Yohei, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Axonal ATP signaling mediates Schwann cell myelination, JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 73P, 2012

    Ino Daisuke, Kanemaru Kazunori, Okubo Yohei, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Imaging of Ca2+ dynamics within the endoplasmic reticulum using a new fluorescent Ca2+ indicator, JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 209P, 2012

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • KCNE1 is essential for inhibition of KCNQ1/KCNE1 currents by insulin, JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 89P, 2012

    Wu Minghua, Norota Ikuo, Kurakami Kazuya, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • ATP-induced inositol 1,4,5-trisphosphate signaling in Schwann cells is required for myelination, JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 69P, 2011

    Ino Daisuke, Kanemaru Kazunori, Okubo Yohei, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • Augmentation of KCNQ1/KCNE1 currents by insulin treatment, JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 262P, 2011

    Wu Minghua, Norota Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Imaging of Ca2+ dynamics within the endoplasmic reticulum using a new fluorescent Ca2+ indicator, JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 166P, 2011

    Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Iino Masamitsu

    Multiple Authorship (Including Foreigners)

  • 電気的リモデリングに対するベプリジルの作用, 心電図 = Electrocardiology, 30(2) , 2010.05

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • Insulin inhibits the KCNQ1/KCNE1 channel expressed in Xenopus oocytes, JOURNAL OF PHARMACOLOGICAL SCIENCES, 112 248P, 2010

    Wu Minghua, Tsutakawa Shusei, Norota Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Possible internalization of the KCNQ1/KCNE1 channel by activation of the alpha(1A) adrenergic receptor, JOURNAL OF PHARMACOLOGICAL SCIENCES, 112 75P, 2010

    Tsutakawa Shusei, Norota Ikuo, Wu Minghua, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • 遺伝子変異動物を用いた心室再分極評価, 心電図 = Electrocardiology, 29(3) 206-207, 2009.06

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • Wortmannin Inhibits the Increase in Myofilament Ca2+ Sensitivity Induced by Cross-Talk of Endothelin-1 With Norepinephrine in Canine Ventricular Myocardium, JOURNAL OF PHARMACOLOGICAL SCIENCES, 109(2) 193-202, 2009.02

    Chu Li, Norota Ikuo, Ishii Kuniaki, Endoh Masao

    Multiple Authorship (Including Foreigners)

  • ウォルトマンニンはイヌ心室心筋におけるエンドセリン1とノルエピネフリンのクロストークにより誘導される筋フィラメントCa2+感受性の増加を阻害する(Wortmannin Inhibits the Increase in Myofilament Ca2+ Sensitivity Induced by Cross-Talk of Endothelin-1 With Norepinephrine in Canine Ventricular Myocardium), Journal of Pharmacological Sciences, 109(2) 193-202, 2009.02

    Chu Li, Norota Ikuo, Ishii Kuniaki, Endoh Masao

    Multiple Authorship (Including Foreigners)

  • Development of improved G-CaMP2-type genetic Ca2+ probe, which minimally enhances cardiac hypertrophic signaling, JOURNAL OF PHARMACOLOGICAL SCIENCES, 109 118P, 2009

    Ohkura Masamichi, Norota Ikuo, Nakai Junichi, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • INTERNALIZATION OF KCNQ1 PROTEIN BY ACTIVATION OF ANGIOTENSIN RECEPTOR TYPE 1, JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 256, 2009

    Ishii Kuniaki, Norota Ikuo, Yamazaki Yoshihiko, Ohkura Masamichi

    Multiple Authorship (Including Foreigners)

  • Mechanisms for internalization of KCNQ1 protein by receptor activation, JOURNAL OF PHARMACOLOGICAL SCIENCES, 109 44P, 2009

    Ishii Kuniaki, Okazaki Masashi, Norota Ikuo, Yamazaki Yoshihiko, Ohkura Masamichi

    Multiple Authorship (Including Foreigners)

  • Involvement of ARF1 in 5-hydroxytryptamine (5-HT)-induced internalization of the 5-HT2A receptor expressed in HEK293 cells, JOURNAL OF PHARMACOLOGICAL SCIENCES, 109 136P, 2009

    Ohkura Masamichi, Norota Ikuo, Tanaka Naoko, Yamamoto Ryuichi, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Cardiac ion channel gene mutations in sudden infant death syndrome., Pediatric research, 64(5) 482-7, 2008.11

    Otagiri T, Kijima K, Osawa M, Ishii K, Makita N, Matoba R, Umetsu K, Hayasaka K

    Multiple Authorship (Including Foreigners)

  • Overexpression of diacylglycerol kinase zeta inhibits endothelia-1-induced decreases in Ca2+ transients and cell shortening in mouse ventricular myocytes, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 44(3) 520-526, 2008.03

    Nishimaru Kazuhide, Arimoto Takahiro, Takeishi Yasuchika, Kubota Isao, Ishii Kuniaki, Endoh Masao

    Multiple Authorship (Including Foreigners)

  • Differential effects of alpha(1A) adrenoceptor activation on I-Ks due to their differential expression levels, JOURNAL OF PHARMACOLOGICAL SCIENCES, 106 86P, 2008

    Yang Yong, Ohkura Masamichi, Norota Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Involvement of the PY motif within KCNQ1 in the modulation of I-Ks by AT(1) receptor activation, JOURNAL OF PHARMACOLOGICAL SCIENCES, 106 86P, 2008

    Ohkura Masamichi, Okazaki Masashi, Norcita Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • DP-107-2 HERGおよびKvLQT1/minKチャネルを共発現させたアフリカツメガエルの卵母細胞を流れる電流に対するE-4031の作用(第107回日本外科学会定期学術集会), 日本外科学会雑誌, 108(2) , 2007.03

    中嶋 和恵, 石井 邦明, 貞弘 光章

    Multiple Authorship (Including Foreigners)

  • Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 175(3) 263-268, 2007.02

    Huqun, Izumi Shinyu, Miyazawa Hitoshi, Ishii Kuniaki, Uchiyama Bine, Ishida Tadashi, Tanaka Sawako, Tazawa Ryushi, Fukuyama Shunichiro, Tanaka Tomoaki, Nagai Yoshiaki, Yokote Akemi, Takahashi Hiroki, ...

    Multiple Authorship (Including Foreigners)

  • Biphasic modulation of the slow component of delayed rectifier K+ currents by angiotensin II., JOURNAL OF PHARMACOLOGICAL SCIENCES, 103 147P, 2007

    Okazaki Masashi, Norota Ikuo, Ishii Kuniaki

    Multiple Authorship (Including Foreigners)

  • Inhibitory effects of dronedarone and amiodarone on HERG+KvLQT1/minK currents, JOURNAL OF PHARMACOLOGICAL SCIENCES, 100 221P, 2006

    Norota I, Nakashima K, Ishii K

    Multiple Authorship (Including Foreigners)

  • Effects of dronedarone on the currents of Xenopus oocytes co-expressing HERG and KvLQt1/mink channels, JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 39(6) 1017-1018, 2005.12

    Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter, CIRCULATION RESEARCH, 96(2) 216-224, 2005.02

    Plane F, Johnson R, Kerr P, Wiehler W, Thorneloe K, Ishii K, Chen T, Cole W

    Multiple Authorship (Including Foreigners)

  • Cross-talk between beta(1)-adrenoceptors and ETA receptors in modulation of the slow component of delayed rectifier K+ currents, NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 371(2) 133-140, 2005.02

    Lin C, Nagai M, Ishigaki D, Hayasaka K, Endoh M, Ishii K

    Multiple Authorship (Including Foreigners)

  • Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium., Journal of pharmacological sciences, 96(2) 199-207, 2004.10

    Chu L, Norota I, Yomogida S, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • イヌ心室筋においてcAMP介在シグナル伝達とのクロストークにより誘導されるエンドセリン-1,アンジオテンシン-IIおよびフェニレフリンの異なった変力作用(Differential Inotropic Effects of Endothelin-1,Angiotensin II,and Phenylephrine Induced by Crosstalk With cAMP-Mediated Signaling Process in Dog Ventricular Myocardium), Journal of Pharmacological Sciences, 96(2) 199-207, 2004.10

    Chu Li, Norota Ikuo, Yomogida Shin-ichi, Ishii Kuniaki, Endoh Masao

    Multiple Authorship (Including Foreigners)

  • Peritumoral CpG oligodeoxynucleotide treatment inhibits tumor growth and metastasis of B16F10 melanoma cells, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 123(2) 395-402, 2004.08

    N Kunikata, K Sano, M Honda, K Ishii, J Matsunaga, R Okuyama, K Takahashi, H Watanabe, G Tamura, H Tagami, T Terui

    Multiple Authorship (Including Foreigners)

  • Differential inhibition by TAK-044 of the inotropic effects of endothelin-1 and endothelin-3, EUROPEAN JOURNAL OF PHARMACOLOGY, 492(2-3) 217-224, 2004.05

    Yomogida S, Maruya J, Norota I, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • Detection of ion channel activity in Xenopus laevis oocytes expressing Influenza C virus CM2 protein, ARCHIVES OF VIROLOGY, 149(1) 35-50, 2004.01

    Hongo S, Ishii K, Mori K, Takashita E, Muraki Y, Matsuzaki Y, Sugawara K

    Multiple Authorship (Including Foreigners)

  • Effects of E-4031 on the currents of Xenopus oocytes expressing HERG and KvLQT1/minK channels, JOURNAL OF PHARMACOLOGICAL SCIENCES, 94 274P, 2004

    Nakashima K, Endoh M, Ishii K

    Multiple Authorship (Including Foreigners)

  • Expression and characterization of rabbit endothelin receptors, JOURNAL OF PHARMACOLOGICAL SCIENCES, 94 273P, 2004

    Yomogida S, Norota I, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • New approach for development of antiarrhythmic drugs, JOURNAL OF PHARMACOLOGICAL SCIENCES, 94 32P, 2004

    Ishii K, Nakashima K, Endoh M

    Multiple Authorship (Including Foreigners)

  • Point mutations that alter coupling between the voltage sensor and the activation gate of HERG channel, JOURNAL OF PHARMACOLOGICAL SCIENCES, 94 272P, 2004

    Ishii K, Nagai M, Endoh M

    Multiple Authorship (Including Foreigners)

  • Differential inhibition of transient outward currents of Kv1.4 and Kv4.3 by endothelin, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 310(2) 634-640, 2003.10

    Hagiwara K, Nunoki K, Ishii K, Abe T, Yanagisawa T

    Multiple Authorship (Including Foreigners)

  • Signal transduction and Ca2+ signaling in contractile regulation induced by crosstalk between endothelin-1 and norepinephrine in dog ventricular myocardium, CIRCULATION RESEARCH, 92(9) 1024-1032, 2003.05

    Chu L, Takahashi R, Norota I, Miyamoto T, Takeishi Y, Ishii K, Kubota I, Endoh M

    Multiple Authorship (Including Foreigners)

  • Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency, CARDIOVASCULAR RESEARCH, 57(3) 651-659, 2003.03

    Ishii K, Nagai M, Takahashi M, Endoh M

    Multiple Authorship (Including Foreigners)

  • Inhibitory action of the phosphatase inhibitor cantharidin on the endothelin-1-induced and the carbachol-induced negative inotropic effect in the canine ventricular myocardium., Journal of cardiovascular pharmacology, 41 Suppl 1 S89-92, 2003.01

    Chu L, Norota I, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • On the coupling between the voltage sensor and the activation gate of HERG channel., JOURNAL OF PHARMACOLOGICAL SCIENCES, 91 87P, 2003

    Ishii K, Nagai M, Endoh M

    Multiple Authorship (Including Foreigners)

  • [Molecular mechanism of heart conduction system]., Nihon rinsho. Japanese journal of clinical medicine, 60(7) 1264-7, 2002.07

    Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method, PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 444(1-2) 107-116, 2002.05

    Ichiyanagi O, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • Dissociation of E-4031 from HERG I647 mutants, JAPANESE JOURNAL OF PHARMACOLOGY, 88 158P, 2002

    Ishii K, Nagai M, Endoh M

    Multiple Authorship (Including Foreigners)

  • Human beta(1)-adrenoceptor and ETA receptor modulate I-Ks currents recorded from oocytes expressing human minK, JAPANESE JOURNAL OF PHARMACOLOGY, 88 159P, 2002

    Lin CQ, Endoh M, Ishii K

    Multiple Authorship (Including Foreigners)

  • Involvement of Rho-kinase in regulation of contractility and cytosolic Ca2+ induced by cross talk of endothelin-1 and norepinephrine in canine ventricular myocardium, JAPANESE JOURNAL OF PHARMACOLOGY, 88 64P, 2002

    Chu L, Tanaka H, Zhang JX, Ishii K, Endoh M

    Multiple Authorship (Including Foreigners)

  • The role of S4-S5 intracellular loops of Kv1.4 and 1.2 in inactivation of Kv1.4/1.2 hybrid channel, JAPANESE JOURNAL OF PHARMACOLOGY, 88 158P, 2002

    Nunoki K, Ishii K, Yanagisawa T

    Multiple Authorship (Including Foreigners)

  • Heteromultimeric Kv1.2-Kv1.5 channels underlie 4-aminopyridine-sensitive delayed rectifier K+ current of rabbit vascular myocytes, CIRCULATION RESEARCH, 89(11) 1038-1044, 2001.11

    PM Kerr, O Clement-Chomienne, KS Thorneloe, TT Chen, K Ishii, DP Sontag, MP Walsh, WC Cole

    Multiple Authorship (Including Foreigners)

  • メタンスルフォンアニリド化合物のHERGチャネルからの解離特性について, 日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA, 118(1) 75P-76P, 2001.10

    石井 邦明, 高橋 昌弘, 遠藤 政夫

    Multiple Authorship (Including Foreigners)

  • An amino acid residue whose change by mutation affects drug binding to the HERG channel, FEBS LETTERS, 506(3) 191-195, 2001.10

    Ishii K, Kondo K, Takahashi M, Kimura M, Endoh M

    Multiple Authorship (Including Foreigners)

  • 成人病とゲノム研究の最前線 メタンスルフォンアニリド化合物のHERGチャネルからの解離特性について, 日本薬理学雑誌, 118(補冊1) 75P-76P, 2001.10

    石井 邦明, 高橋 昌弘, 遠藤 政夫

    Multiple Authorship (Including Foreigners)

  • Differential sensitivity of Kv1.4, Kv1.2, and their tandem channel to acidic pH: Involvement of a histidine residue in high sensitivity to acidic pH, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 296(2) 405-411, 2001.02

    Ishii K, Nunoki K, Yamagishi T, Okada H, Taira N

    Multiple Authorship (Including Foreigners)

  • Differential sensitivity of Kv1.4, Kv1.2, and their tandem channel to acidic pH: involvement of a histidine residue in high sensitivity to acidic pH, J. Phar. Exp. Ther., 296 (2001), 2001.01

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • Differential sensitivity of kv1.4, Kv1.2, and Their tandem channel to acidic ph: Involvement of a histidine residue in high sensitivity to acidic ph, Journal of Pharmacology and Experimental Therapeutics, 296(2) 405-411, 2001

    Kuniaki Ishii, Kazuo Nunoki, Toshio Yamagishi, Hitoshi Okada, Norio Taira

    Multiple Authorship (Including Foreigners)

  • Inhibition of the K+ channel Kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation, JOURNAL OF PHYSIOLOGY-LONDON, 526(2) 253-264, 2000.07

    Claydon TW, Boyett MR, Sivaprasadarao A, Ishii K, Owen JM, O'Beirne HA, Leach R, Komukai K, Orchard CH

    Multiple Authorship (Including Foreigners)

  • Identification, cloning and expression of rabbit vascular smooth muscle Kv1.5 and comparison with native delayed rectifier K(+) current, JOURNAL OF PHYSIOLOGY-LONDON, 515(3) 653-667, 1999.03

    Clement-Chomienne O, Ishii K, Walsh MP, Cole WC

    Multiple Authorship (Including Foreigners)

  • Permeation of voltage-dependent potassium channels, POTASSIUM ION CHANNELS, 46 47-66, 1999

    Ishii K

    Multiple Authorship (Including Foreigners)

  • ミニ・レビュー イオンチャンネルの分子生物学(3) 電位依存性Kチャネルの分子生物学, 心臓, 30(3) 129-136, 1998

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • Cloning and expression in mammalian cells of Kv1.5 channels of rabbit portal vein vascular smooth muscle, BIOPHYSICAL JOURNAL, 72(2) THP12, 1997.02

    ClementChomienne O, Ishii K, Walsh MP, Cole WC

    Multiple Authorship (Including Foreigners)

  • C3 production of cultured human epidermal keratinocytes is enhanced by IFN gamma and TNF alpha through different pathways, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 108(1) 62-67, 1997.01

    Terui T, Ishii K, Ozawa M, Tabata N, Kato T, Tagami H

    Multiple Authorship (Including Foreigners)

  • SINGLE CHANNEL CHARACTERISTICS OF THE INWARD RECTIFIER K CHANNEL CLONED FROM VENTRICULAR CELLS, Japanese circulation journal, 60(7) 415, 1996.06

    NAGASHIMA Masato, ISHII Kuniaki, TOHSE Noritsugu, TAIRA Norio, YABU Hideyo

    Multiple Authorship (Including Foreigners)

  • 0314 心室筋よりクローニングされた内向き整流性カリウムチャネルの単一チャネル特性について, Japanese circulation journal, 60(0) , 1996.02

    長島 雅人, 當瀬 規嗣, 薮 英世, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • The voltage-dependent K+ channel (Kv1.5) cloned from rabbit heart and facilitation of inactivation of the delayed rectifier current by the rat beta subunit (vol 372, pg 20, 1995), FEBS LETTERS, 379(2) 202, 1996.01

    Sasaki Y, Ishii K, Nunoki K, Yamagishi T, Taira N

    Multiple Authorship (Including Foreigners)

  • DETERMINATION OF K-A VALUES BY CONTROLLED RECEPTOR EXPRESSION IN XENOPUS OOCYTES, BRITISH JOURNAL OF PHARMACOLOGY, 116(3) 2062-2066, 1995.10

    MURAKOSHI H, NUNOKI K, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • THE VOLTAGE-DEPENDENT K+ CHANNEL (KV1.5) CLONED FROM RABBIT HEART AND FACILITATION OF INACTIVATION OF THE DELAYED RECTIFIER CURRENT BY THE RAT BETA-SUBUNIT, FEBS LETTERS, 372(1) 20-24, 1995.09

    SASAKI Y, ISHII K, NUNOKI K, YAMAGISHI T, TAIRA N

    Multiple Authorship (Including Foreigners)

  • ANTIARRHYTHMIC AND BRADYCARDIAC DRUGS INHIBIT CURRENTS OF CLONED K+ CHANNELS, K-V1.2 AND K-V1.4, EUROPEAN JOURNAL OF PHARMACOLOGY, 281(2) 151-159, 1995.08

    YAMAGISHI T, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • CLONING OF A SWELLING-INDUCED CHLORIDE CURRENT RELATED PROTEIN FROM RABBIT HEART, BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1234(1) 145-148, 1995.03

    OKADA H, ISHII K, NUNOKI K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Cloning of a swelling-induced chloride current related protein from rabbit heart, BBA - Biomembranes, 1234 145-148, 1995.03

    Hitoshi Okada, Kuniaki Ishii, Kazuo Nunoki, Norio Taira

    Multiple Authorship (Including Foreigners)

  • 0635 異なった受容体の刺激による心筋Kチャンネルクローンの修飾, Japanese circulation journal, 59(0) , 1995.03

    村越 秀行, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • 0636 KチャネルクローンKv1.2の4-aminopyridine感受性部位に関する検討, Japanese circulation journal, 59(0) , 1995.03

    山岸 俊夫, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • 心筋K+チャネルクローンの薬理学, 心電図, 15(2) 124-129, 1995.03

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • AMINO-ACID-RESIDUES RESPONSIBLE FOR SENSITIVITY TO PH OF CLONED K+ CHANNELS, HEART AND VESSELS, 12-13, 1995

    ISHII K, YAMAGISHI T, NUNOKI K, OKADA H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • EFFECTS OF ANTIARRHYTHMIC AND BRADYCARDIAC DRUGS ON CLONED CARDIAC K+ CHANNELS, HEART AND VESSELS, 153-154, 1995

    YAMAGISHI T, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Determination of KA values by controlled receptor expression in Xenopus oocytes, British Journal of Pharmacology, 116(3) 2062-2066, 1995

    Hideyuki Murakoshi, Kazuo Nunoki, Kuniaki Ishii, Norio Taira

    Multiple Authorship (Including Foreigners)

  • HYBRID POTASSIUM CHANNELS BY TANDEM LINKAGE OF INACTIVATING AND NONINACTIVATING SUBUNITS, JOURNAL OF BIOLOGICAL CHEMISTRY, 269(39) 24138-24142, 1994.09

    NUNOKI K, ISHII K, OKADA H, YAMAGISHI T, MURAKOSHI H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • RECEPTOR-MEDIATED MODULATION OF RAT K-V1.2 IN XENOPUS-OOCYTES, EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION, 268(3) 451-454, 1994.08

    H MURAKOSHI, K ISHII, K NUNOKI, N TAIRA

    Multiple Authorship (Including Foreigners)

  • 心筋Kチャネルの構造の修飾機構, 心臓, 26(7) 782-788, 1994.07

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • Kv1. 4及びKv1. 2のタンデム連結によるハイブリッドKチャンネルの不活性化 : 第58回日本循環器学会学術集会, Japanese circulation journal, 58(0) , 1994.03

    布木 和夫, 石井 邦明, 岡田 斉, 山岸 俊夫, 村越 秀行, 平 則夫

    Multiple Authorship (Including Foreigners)

  • 受容体を介した遅延整流型心筋Kチャンネルクローン(Kv1.2)の修飾機構 : 第58回日本循環器学会学術集会, Japanese circulation journal, 58(0) , 1994.03

    村越 秀行, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • クローン化心筋Kチャネルに対する抗不整脈薬及び徐拍薬の作用 : 第58回日本循環器学会学術集会, Japanese circulation journal, 58(0) , 1994.03

    山岸 俊夫, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • ウサギ 心筋よりクローニングしたMDCK型クロライドチャネルの一次構造とその性質 : 第58回日本循環器学会学術集会, Japanese circulation journal, 58(0) , 1994.03

    岡田 斉, 石井 邦明, 布木 和夫, 平 則夫

    Multiple Authorship (Including Foreigners)

  • Hybrid potassium channels by tandem linkage of inactivating and non- inactivating subunits, Journal of Biological Chemistry, 269(39) 24138-24142, 1994

    K. Nunoki, K. Ishii, H. Okada, T. Yamagishi, H. Murakoshi, N. Taira

    Multiple Authorship (Including Foreigners)

  • PARTICIPATION OF NONINACTIVATING SUBUNIT IN INACTIVATION OF HETEROMULTIMERIC K-CHANNELS, CIRCULATION, 88(4) 34, 1993.10

    NUNOKI K, ISHII K, OKADA H, YAMAGISHI T, MURAKOSHI H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Molecular cloning and expression of a rat cDNA encoding MDCK-type chloride channel, BBA - Gene Structure and Expression, 1173(3) 353-356, 1993.06

    Takaaki Abe, Kazuhisa Takeuchi, Kuniaki Ishii, Keishi Abe

    Multiple Authorship (Including Foreigners)

  • 分子循環器病学 心筋細胞の膜イオン輸送の分子生物学 イオンチャンネルの分子構造,機能,調節 K+チャンネル, 日本臨床, 51(6) 1477-1482, 1993.06

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • クローン化した心臓病患者のKチャンネルに対するクラス3抗不整脈剤の効果の欠損, The Japanese Journal of Pharmacology, 61(4) 371-373, 1993.04

    Yamagishi Toshio, Ishii Kuniaki, Taira Norio

    Multiple Authorship (Including Foreigners)

  • ラット心筋よりcloningしたK channelとその修飾機構 : 口述発表 : 第57回日本循環器学会学術集会, Japanese circulation journal, 57(0) , 1993.03

    岡田 斉, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • 心筋Kチャネルクローンに対してクラスIII抗不整脈薬は作用しない : 口述発表 : 第57回日本循環器学会学術集会, Japanese circulation journal, 57(0) , 1993.03

    山岸 俊夫, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • ICI-147,798 CAUSES INSURMOUNTABLE ANTAGONISM AGAINST T-0509, A SELECTIVE BETA-1-ADRENOCEPTOR AGONIST, BUT SURMOUNTABLE ANTAGONISM AGAINST ISOPROTERENOL, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 21(2) 323-331, 1993.02

    TOFUKUJI M, YANAGISAWA T, KUROSAWA H, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • 不整脈研究の最前線 心筋Kチャンネルクローンの修飾機構, 心臓, 25(2) 223-227, 1993.02

    石井 邦明, 岡田 斉, 布木 和夫

    Multiple Authorship (Including Foreigners)

  • CLONING AND MODULATION BY ENDOTHELIN-1 OF RAT CARDIAC K-CHANNEL, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 184(3) 1484-1489, 1992.05

    ISHII K, NUNOKI K, MURAKOSHI H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • 陽性変力作用に関与する親和性の異なる2つのβ1-受容体, 心臓, 23(Suppl.2) 19-22, 1991.10

    柳沢 輝行, 東福寺 元久, 石井 邦明

    Multiple Authorship (Including Foreigners)

  • 新しい水溶性ジヒドロピリジン系カルシウム拮抗薬NKY-722の陰性変力作用 ジヒドロピリジン受容部位と他の受容部位, 薬理と治療, 18(Suppl.2) 317-323, 1990.03

    柳沢 輝行, 今川 純一, 石井 邦明

    Multiple Authorship (Including Foreigners)

  • AN EXPLANATION OF BELL-SHAPED, DOSE-POSITIVE INOTROPIC EFFECT CURVES FOR DENOPAMINE IN CANINE RIGHT VENTRICULAR MUSCLE, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 14(4) 570-576, 1989.10

    YOKOYAMA H, ISHII K, YANAGISAWA T, TAIRA N

    Multiple Authorship (Including Foreigners)

  • An explanation of bell-shaped, dose-positive inotropic effect curves for denopamine in canine right ventricular muscle, Journal of Cardiovascular Pharmacology, 14 570-576, 1989.01

    Hitoshi Yokoyama, Kuniaki Ishii, Teruyuki Yanagisawa, Norio Taira

    Multiple Authorship (Including Foreigners)

  • Differential coupling to positive inotropic responses of cyclic AMP produced by stimulation of β<inf>1</inf>- and β<inf>2</inf>-adrenergic receptors, Journal of Cardiovascular Pharmacology, 13 64-75, 1989.01

    T. Yanagisawa, K. Ishii, H. Hashimoto, N. Taira

    Multiple Authorship (Including Foreigners)

  • DIFFERENTIAL COUPLING TO POSITIVE INOTROPIC RESPONSES OF CYCLIC-AMP PRODUCED BY STIMULATION OF BETA-1-ADRENERGIC AND BETA-2-ADRENERGIC RECEPTORS, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 13(1) 64-75, 1989.01

    YANAGISAWA T, ISHII K, HASHIMOTO H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • β1およびβ2受容体を介する陽性変力作用, 心臓, 20(Suppl.1) 9-14, 1988.10

    柳沢 輝行, 石井 邦明, 橋本 博雄

    Multiple Authorship (Including Foreigners)

  • Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation, British Journal of Pharmacology, 93(93) 146-150, 1988.01

    Yoshinori Sato, Kuniaki Ishii, Norio Taira

    Multiple Authorship (Including Foreigners)

  • DIFFERENTIAL ANTAGONISM BY BAY-K-8644 OF VASODILATOR EFFECTS OF NIFEDIPINE, DILTIAZEM, NICORANDIL AND NITROGLYCERIN IN DOG FEMORAL CIRCULATION, BRITISH JOURNAL OF PHARMACOLOGY, 93(1) 146-150, 1988.01

    SATO Y, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • COMPARISON OF VASODILATOR EFFECTS OF DN-9693, A SELECTIVE INHIBITOR OF CYCLIC-AMP PHOSPHODIESTERASE, AND ISOBUTYLMETHYLXANTHINE, A NONSELECTIVE ONE, IN DOGS, JAPANESE JOURNAL OF PHARMACOLOGY, 44(4) 405-412, 1987.08

    HASHIMOTO H, ISHII K, SATOH K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Cyclic AMP phosphodiesteraseの選択的抑制薬のDN-9693と同非選択性のisobutylmethylxanthineのイヌ血管拡張効果の比較, The Japanese Journal of Pharmacology, 44(4) 405-412, 1987.08

    Hashimoto Hiroo, Ishii Kuniaki, Satoh Keisuke

    Multiple Authorship (Including Foreigners)

  • ANTITACHYCARDIAC EFFECT OF OPC-8212, A NOVEL CARDIOTONIC AGENT, ON TACHYCARDIAC RESPONSES OF GUINEA-PIG ISOLATED RIGHT ATRIA TO ISOPROTERENOL AND HISTAMINE, JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 10(1) 47-54, 1987.07

    YANAGISAWA T, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Antitachycardiac effect of OPC-8212, a novel cardiotonic agent, on tachycardiac responses of guinea pig isolated right atria to isoproterenol and histamine, Journal of Cardiovascular Pharmacology, 10 47-54, 1987.01

    Teruyuki Yanagisawa, Kuniaki Ishii, Norio Taira

    Multiple Authorship (Including Foreigners)

  • DIFFERENTIAL INVOLVEMENT OF BETA-1-RECEPTORS AND BETA-2-RECEPTORS IN POSITIVE INOTROPY AND CAMP LEVELS IN CANINE VENTRICULAR MUSCLE, JAPANESE JOURNAL OF PHARMACOLOGY, 43 P171, 1987

    YANAGISAWA T, ISHII K, HASHIMOTO H, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Comparison of Vasodilator Effects of DN-9693, a Selective Inhibitor of Cyclic AMP Phosphodiesterase, and Isobutylmethylxanthine, a Non-Selective One, in Dogs, The Japanese Journal of Pharmacology, 44(4) 405-412, 1987

    Hiroo Hashimoto, Kuniaki Ishii, Keisuke Satoh, Norio Taira

    Multiple Authorship (Including Foreigners)

  • イヌ摘出心筋におけるCaアゴニストBay k 8644とCa拮抗薬との相互作用, 東北医学雑誌, 99(1〜2) 40-42, 1986.12

    石井 邦明

    Multiple Authorship (Including Foreigners)

  • 〔カテコールアミン〕カテコールアミンの頻拍作用に対するイオンコンダクタンスに影響する薬物の効果 抗頻拍作用, 呼吸と循環, 34(11) 1153-1158, 1986.11

    柳沢 輝行, 石井 邦明, 平 則夫

    Multiple Authorship (Including Foreigners)

  • Similarity and dissimilarity of the vasoconstrictor effects of Bay K 8644 on coronary, femoral, mesenteric and renal circulations of dogs, British Journal of Pharmacology, 88 369-377, 1986.01

    Kuniaki Ishii, Yoshinori Sato, Norio Taira

    Multiple Authorship (Including Foreigners)

  • INTERACTION BETWEEN BAY-K-8644 AND SOME VASODILATORS IN THE DOG HINDLIMB VASCULATURE, JAPANESE JOURNAL OF PHARMACOLOGY, 40 P99, 1986

    SATO Y, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • THE IONIC MECHANISM OF ACTION OF THE POSITIVE CHRONOTROPIC EFFECT OF ISOPROTERENOL ANALYZED BY AGENTS THAT AFFECT IONIC CONDUCTANCE, JAPANESE JOURNAL OF PHARMACOLOGY, 40 P199, 1986

    YANAGISAWA T, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • Diltiazem, Nifedipine, Verapamil及びNicorandilによるサル冠状動脈の自動律動収縮の消失とnitroglycerinの無作用について, The Tohoku Journal of Experimental Medicine, 145(1) 85-90, 1985.01

    Ishii Kuniaki, Yanagisawa Teruyuki, Satoh Keisuke

    Multiple Authorship (Including Foreigners)

  • DIFFERENTIAL ANTAGONISM BY BAY-K-8644, A DIHYDROPYRIDINE CALCIUM AGONIST, OF THE NEGATIVE INOTROPIC EFFECTS OF NIFEDIPINE, VERAPAMIL, DILTIAZEM AND MANGANESE IONS IN CANINE VENTRICULAR MUSCLE, BRITISH JOURNAL OF PHARMACOLOGY, 84(2) 577-584, 1985

    ISHII K, TAIRA N, YANAGISAWA T

    Multiple Authorship (Including Foreigners)

  • THE MECHANISM OF ANTITACHYCARDIC EFFECT OF OPC-8212, A NOVEL POSITIVE INOTROPIC DRUG, IN GUINEA-PIG RIGHT ATRIA, JAPANESE JOURNAL OF PHARMACOLOGY, 39 P137, 1985

    YANAGISAWA T, ISHII K, TAIRA N

    Multiple Authorship (Including Foreigners)

  • ANTITACHYCARDIAC EFFECT OF OPC-8212, A NOVEL POSITIVE INOTROPIC DRUG, IN GUINEA-PIG RIGHT ATRIA, JAPANESE JOURNAL OF PHARMACOLOGY, 36 P276, 1984

    ISHII K, YANAGISAWA T, TAIRA N

    Multiple Authorship (Including Foreigners)

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Books

  • Modulation of transient type K channel cloned from rat heart, Biochem. Biophys. Res. Commun. Ⅰ189(1992)(共著), 2001.01

    石井 邦明

  • Cloning and modulation by endothelin-1 of rat cardiac K channel, Biochem. Biophys. Res. Commun., Ⅰ184(1992)(共著), 1900.01

    石井 邦明

  • A mammalian transient type K+ channel, rat Kv1.4, has two potential domains that could produce rapid inactivation, J. Biol. Chem., Ⅰ272(1997)(共著), 1900.01

    石井 邦明

  • Voltage-dependent K+ channel(Kv1.5)cloned from rabbit heart and facilitation of inactivation of delayed rectifier current by rat β subunit. FEBS Lett., Ⅰ372(1995)(共著), 1900.01

    石井 邦明

  • Hybrid potassium channls by tandem linkage of inactivating and non-inactivating subunits. J. Biol. Chem., Ⅰ269(1994)(共著), 1900.01

    石井 邦明

  • Cloning and functional expression of a cardiac inward rectifier K+channel. FEBS Lett. Ⅰ338(1994)(共著), 1900.01

    石井 邦明

  • イオンチャネルの分子構造,機能,調節-K+チャネル,日本臨床51(1993), 1900.01

    石井 邦明

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Review Papers

  • Dissociation of methanesulfonanilides from the HERG mutant channel, Folia Pharmacologica Japonica, 118 , 2001.12

    Kuniaki Ishii, Masahiro Takahashi, Masao Endoh

  • Pharnacology of cloned cardiac K+ channels., Japanese Heart Rhythm Society, Japanese Journal of Electrocardiology, 15(2) 124-129, 1995

    Ishii Kuniaki

  • Structure and modulation of cardiac K channels, Japan Heart Foundation, Shinzo, 26(26) 782-792, 1994

    Ishii Kuniaki

  • Molecular structure, function and regulation of K+ channels, Nippon rinsho. Japanese journal of clinical medicine, 51 1477-1482, 1993.01

    K. Ishii

  • Mechanisms of modulation of cloned cardiac K channels, Japan Heart Foundation, Shinzo, 25(25) 223-227, 1993

    Ishii Kuniaki, Okada Hitoshi, Nunoki Kazuo, Taira Norio

Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Scientific Research(C),2020.04 - 2023.03