Research Areas
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Life Science / Functional biochemistry
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Life Science / Dermatology
Graduating School
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Nagoya University, Faculty of Science
1979.03, Graduated
Graduate School
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Nagoya University, Graduate School, Division of Natural Science
Doctor's Course, 1984.07, Completed
External Career
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St.Marianna University School of Medicine, Research Assistant, 1986.09 - 1990.03
Papers
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A terminal 6-sulfotransferase catalyzing a synthesis of N-acetylgalactosamine 4,6-bissulfate residue at the nonreducing terminal position of chondroitin sulfate., Journal of Biological Chemistry, 256(11) 5443-5449, 1981.06
Yasuo Nakanishi, Masatoshi Shimizu, Kaoru Otsu, Shigemi Kato, Masahiro Tsuji, and Sakaru Suzuki
Multiple Authorship (Including Foreigners)
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Enzymatic transfer of galactosyl phosphate from UDP-galactose to UDP-N-acetylglucosamine., FEBS Letter, 151(1) 15-18, 1983.01
Yasuo Nakanishi, Kaoru Otsu, and Sakaru Suzuki
Multiple Authorship (Including Foreigners)
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A sulfotransferase-sulfatase system in avian oviduct which catalyzes a conversion of UDP-N-acetylgalactosamine 4-sulfate to the 6-sulfate isomer., Journal of Biological Chemistry, 259(10) 6403-6410, 1984.05
Kaoru Otsu, Hirofumi Inoue, Yasuo Nakanishi, Shigemi Kato, Masahiro Tsuji, and Sakaru Suzuki
Multiple Authorship (Including Foreigners)
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A distinct terminal structure in newly synthesized chondroitin sulphate chains., Biochemical Journal, 227(1) 37-48, 1985.04
Kaoru Otsu, Hirofumi Inoue, Yoshie Tsuziki, Hideto Yonekura, Yasuo Nakanishi, and Sakaru Suzuki
Multiple Authorship (Including Foreigners)
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Purification and analysis of the core protein of the protease-resistant intracellular chondroitin sulfate E proteoglycan from the interleukin 3-dependent mouse mast cell., Journal of Biological Chemistry, 260(26) 14194-14200, 1985.11
Richard L. Stevens, Kaoru Otsu, and K. Frank Austen
Multiple Authorship (Including Foreigners)
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Glycosaminoglycan sulfotransferases in human and animal sera., Journal of Biological Chemistry, 261(10) 4460-4469, 1986.04
Hirofumi Inoue, Kaoru Otsu, Masahiko Yoneda, Koji Kimata, Sakaru Suzuki, and Yasuo Nakanishi
Multiple Authorship (Including Foreigners)
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Release of inorganic sulfate ion under mild alkaline conditions from sulfated, unsaturated disaccharides obtained from chondroitin sulfates by chondroitinase digestion., Carbohydrate Research, 155 277-282, 1986.11
Hirofumi Inoue, Ryoichi Nakayama, Kaoru Otsu, Hiroko Habuchi, Sakaru Suzuki, and Yasuo Nakanishi
Multiple Authorship (Including Foreigners)
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Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells., Journal of Experimental Medicine, 165(3) 615-627, 1987.03
Kaoru Otsu, Toru Nakano, Yuzuru Kanakura, Hideki Asai, Howard R. Katz, K. Frank Austen, Richard L. Stevens, Stephen J. Galli, and Yukihiko Kitamura
Multiple Authorship (Including Foreigners)
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Co-sedimentation of chondroitin sulfate A glycosaminoglycans and proteoglycans with the cytolytic secretory granules of rat large granular lymphocyte (LGL) tumor cells, and identification of a mRNA in normal and transformed LGL that encodes proteoglycans., Journal of Immunology, 139(3) 863-868, 1987.08
Richard L. Stevens, Kaoru Otsu, John H. Weis, Ramana V. Tantravahi, K. Frank Austen, Pierre A. Henkart, M. Cristina Galli, and Craig W. Reynolds
Multiple Authorship (Including Foreigners)
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Aberrant regulation of the metabolism of the insulin receptor in Swarm rat chondrosarcoma chondrocytes., Biochemical Journal , 254(1) 203-209, 1988.08
Kaoru Otsu, Edward S. Geary, and Richard L. Stevens
Multiple Authorship (Including Foreigners)
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Concurrent changes in sinusoidal expression of laminin and affinity of hepatocytes to laminin during rat liver regeneration., Experimental Cell Research 198 (1): 59-68, 198(1) 59-68, 1992.01
Shigemi Kato, Kaoru Otsu, Kumiko Ohtake, Yoshitada Kimura, Takashi Yashiro, Takuro Suzuki, and Nobu Akamatsu
Multiple Authorship (Including Foreigners)
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Alteration of rat liver proteoglycans during regeneration., Archives of Biochemistry and Biophysics, 294(2) 544-549, 1992.05
Kaoru Otsu, Shigemi Kato, Kumiko Ohtake, and Nobu Akamatsu
Multiple Authorship (Including Foreigners)
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A novel growth-inducible gene that encodes a protein with a conserved cold-shock domain., Nucleic Acids Research , 22(11) 2036-2041, 1994.06
Kikukatsu Ito, Ken-ichi Tsutsumi, Takejiro Kuzumaki, Paul F. Gomez, Kaoru Otsu, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Dietary and hormonal regulation of aldolase B gene transcription in rat liver., Archives of Biochemistry and Biophysics, 314(2) 307-314, 1994.11
Paul F. Gomez, Kikukatsu Ito, Young Huang, Kaoru Otsu, Takejiro Kuzumaki, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Interleukin-6 down-regulates expressions of the aldolase B and albumin genes through a pathway involving the activation of tyrosine kinase., Arch. Biochem. Biophys., Ⅰ320(2)(1995)(共著), Archives of Biochemistry and Biophysics , 320(2) 203-209, 1995.07
大津 芳
Multiple Authorship (Including Foreigners)
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Hormonal regulation of aldolase B gene expression in rat primary cultured hepatocytes., Archives of Biochemistry and Biophysics, 350(2) 291-297, 1998.02
Jun-itsu Ito, Takejiro Kuzumaki, Kaoru Otsu, Yoshihito Iuchi, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Synergistic induction by collagen and fibronectin of liver-specific genes in rat primary cultured hepatocytes., Archives of Biochemistry and Biophysics, 358(1) 58-62, 1998.10
Hisako Ouchi, Kaoru Otsu, Takejiro Kuzumaki, Yoshihito Iuchi, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Sandwich configuration of type I collagen suppresses progesterone production in primary cultured porcine granulosa cells by reducing gene expression of cytochrome P450 cholesterol side-chain cleavage enzyme., Archives of Biochemistry and Biophysics, 376(1) 117-123, 2000.04
Xia Wang, Kaoru Otsu, Hidekazu Saito, Masahiko Hiroi, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Characterization of the responsive elements to hormones in the rat aldolase B gene., Archives of Biochemistry and Biophysics, 377(1) 58-64, 2000.05
Yumiko Takano, Yoshihito Iuchi, Jun-itsu Ito, Kaoru Otsu, Takejiro Kuzumaki, and Kiichi Ishikawa
Multiple Authorship (Including Foreigners)
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Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix., Cellular Physiology and Biochemistry, 11(1) 33-40, 2001.02
Kaoru Otsu, Kikukatsu Ito, Takejiro Kuzumaki, and Yoshihito Iuchi
Multiple Authorship (Including Foreigners)
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Identification of rab7 as a melanosome-associated protein involved in the intracellular transport of tyrosinase-related protein1., Journal of Investigative Dermatology, 117(1) 81-90, 2001.07
Paul F. Gomez, Dong Luo, Kuninori Hirosaki, Kyoka Shinoda, Toshihsru Yamashita, Jun-ichi Suzuki, Kaoru Otsu, Kiichi Ishikawa, and Kowichi Jimbow
Multiple Authorship (Including Foreigners)
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Accumulation of manganese superoxide dismutase under metal-depleted conditions: proposed role for zinc ions in cellular redox balance., Biochemical Journal, 377(1) 241-248, 2004.01
Kaoru Otsu, Yositaka Ikeda, and Junichi Fujii
Multiple Authorship (Including Foreigners)
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Specific inactivation of cysteine protease-type cathepsin by singlet oxygen generated from naphthalene endoperoxides., Biochemical and Biophysical Research Communication , 331(1) 215-223, 2005.05
Yuki Nagaoka, Kaoru Otsu, Futoshi Okada, Kazuaki Sato, Yoshihiro Ohba, Naoki Kotani, and Junichi Fujii
Multiple Authorship (Including Foreigners)
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Abortive apoptotic pathway by singlet oxygen due to the suppression of caspase activation., Biochemical Journal, 389(1) 197-206, 2005.07
Kaoru Otsu, Kazuaki Sato, Yoshitaka Ikeda, Hirotaka Imai, Yasuhito Nakadawa, Yoshihiro Ohba, and Junichi Fujii
Multiple Authorship (Including Foreigners)
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Comparison of keratin expression in cultured human adenocarcinoma cell lines., Journal of dermatological science, 55(1) 59-61, 2009.07
Yamashita M, Takahashi K, Sato M, Otsu K, Hirayama T, Katagata Y
Multiple Authorship (Including Foreigners)
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Impaired activation of caspase cascade during cell death induced by newly synthesized singlet oxygen generator, 1-buthylnaphthalene-4-propionate endoperoxide., Cell biology international, 32(11) 1380-7, 2008.11
Otsu K, Sato K, Sato M, Ono H, Ohba Y, Katagata Y
Multiple Authorship (Including Foreigners)