2024/11/28 更新

写真a

ホッタ ジュンイチ
堀田 純一
HOTTA Jun-ichi
職名
准教授

研究分野

  • ライフサイエンス / 生物物理学

  • ナノテク・材料 / 生物分子化学

  • ナノテク・材料 / ナノ材料科学

  • ナノテク・材料 / 光工学、光量子科学

取得学位

  • 博士(工学),大阪大学,1998年03月

所属学会・委員会

  • 応用物理学会

  • 日本化学会

  • 光化学協会

  • 光化学協会

  • アメリカ光学会

 

研究テーマ

  • 1. 単一分子分光
    2. 超解像蛍光顕微鏡
    3. 珪藻のバイオミネラリゼーション

研究経歴

  • 超解像光学顕微鏡の開発,2005年05月 ~ 継続中

    光ナノ計測

論文

  • Establishment of a simple method for cryopreservation of the marine diatoms, Chaetoceros and Phaeodactylum,JOURNAL OF APPLIED PHYCOLOGY,2023年07月

    Yamaguchi Haruo, Sumida Narumi, Matsukawa Kazutsugu, Adachi Masao, Tomaru Yuji, Ishikawa Kosuke, Hotta Jun-ichi

    単著

  • Cloning and structural basis of fluorescent protein color variants from identical species of sea anemone, Diadumene lineata,PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES,22(7) 1591-1601,2023年03月

    Horiuchi Yuki, Makabe Koki, Laskaratou Danai, Hatori Kuniyuki, Sliwa Michel, Mizuno Hideaki, Hotta Jun-ichi

    単著

  • Fluorescence microscopic imaging of single desmin intermediate filaments elongated by the presence of divalent cations in vitro.,Biophysical chemistry,287 106839,2022年08月

    Sato M, Ishizaka T, Hotta JI, Hatori K

    単著

  • Frame-Insensitive Expression Cloning of Fluorescent Protein from Scolionema suvaense,International Journal of Molecular Sciences,19(2) 371,2018年02月

    Yuki Horiuchi, Danai Laskaratou, Michel Sliwa, Cyril Ruckebusch, Kuniyuki Hatori, Hideaki Mizuno, Jun-ichi Hotta

    共著(海外含む)

  • Adhesion and Disintegration Phenomena on Fractal Agar Gel Surfaces,ournal of Oleo Science,65(11) 909-912,2016年11月

    Ayano Kudo, Marika Sato, Haruna Sawaguchi, Jun-ichi Hotta, Hiroyuki Mayama, Yoshimune Nonomura

    共著(海外含む)

  • Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release,CARDIOVASCULAR RESEARCH,108(3) 387-398,2015年12月

    N. Macquaide, H.-T. M. Tuan, J. Hotta, W. Sempels, I. Lenaerts, P. Holemans, J. Hofkens, M. S. Jafri, R. Willems, K. R. Sipido

    共著(海外含む)

  • Drag force on micron-sized objects with different surface morphologies in a flow with a small Reynolds number,POLYMER JOURNAL,47(8) 564-570,2015年08月

    A. M. R. Kabir, D. Inoue, Y. Kishimoto, J. Hotta, K. Sasaki, N. Kitamura, J. P. Gong, H. Mayama, A. Kakugo

    共著(海外含む)

  • Time-resolved fluorescence methods (IUPAC Technical Report),PURE AND APPLIED CHEMISTRY,86 1969-1998,2014年12月

    H. Lemmetyinen, N. V. Tkachenko, B. Valeur, J. Hotta, M. Ameloot, N. P. Ernsting, T. Gustavsson, N. Boens

    共著(海外含む)

  • Wetting dynamics of colloidal dispersions on agar gel surfaces,COLLOIDS AND SURFACES B-BIOINTERFACES,122 1-6,2014年10月

    E. Seino, S. Chida, H. Mayama, J. Hotta, Y. Nonomura

    共著(海外含む)

  • Experimental evaluation of diffusion constant in a thin polymer film by triplet lifetime analysis of single molecules,OURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,238 ,2012年06月

    T. Chiba, H. Fujiwara, J. Hotta, S. Takeuchi, K. Sasaki

    共著(海外含む)

  • The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering,NUCLEIC ACIDS RESEARCH,39(4) 1310-1325,2011年03月

    J. Hendrix, R. Gijsbers, J. De Rijck, A. Voet, J. Hotta, M. McNeely, J. Hofkens, Z. Debyser, Y. Engelborghs

    共著(海外含む)

  • DNA fluorocode: A single molecule, optical map of DNA with nanometre resolution(共著),Chemical Science,1(4) 453-460,2010年10月

    R. K. Neely, P. Dedecker, J. Hotta, G. Urbanaviciute, S. Klimasauskas, J. Hofkens

    共著(海外含む)

  • Data storage based on photochromic and photoconvertible fluorescent proteins(共著),Journal of Biotechnology,149(9) 289-298,2010年09月

    V. Adam, H. Mizuno, A. Grichine, J. Hotta, Y. Yamagata, B. Moeyaert, G. U. Nienhaus, A. Miyawaki, D. Bourgeois, J. Hofkens

    共著(海外含む)

  • Spectroscopic Rationale for Efficient Stimulated-Emission Depletion Microscopy Fluorophores(共著),Journal of the American Chemical Society,132(14) 5021-5023,2010年03月

    J. Hotta, E. Fron, P. Dedecker, K.P.F. Janssen, C. Li, K. Müllen, B. Harke, J. Bückers, S. W. Hell, J. Hofkens

    共著(海外含む)

  • Transfection of living HeLa cells with fluorescent poly-cytosine encapsulated Ag nanoclusters(共著),Photochemical & Photobiological Science,9(5) 716-721,2010年03月

    Y. Antoku, J. Hotta, H. Mizuno, R. M. Dickson, J. Hofkens, T. Vosch

    共著(海外含む)

  • Optical Encoding of Silver Zeolite Microcarriers(共著),Advanced Materials,22(9) 957-960,2010年03月

    G. De Cremer, B. F. Sels, J. Hotta, M. B.J. Roeffaers, E. Bartholomeeusen, E. Coutiño-Gonzalez, V. Valtchev, D. E. De Vos, T. Vosch, J. Hofkens

    共著(海外含む)

  • Improved Method for Counting DNA Molecules on Biofunctionalized Nanoparticles(共著),Langmuir,26(3) 1594-1597,2010年02月

    F. Delport, A. Deres, J. Hotta, J. Pollet, B. Verbruggen, B. Sels, J. Hofkens, J. Lammertyn

    共著(海外含む)

  • Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser(共著),Molecular Crystals and Liquid Crystals,505 457-468,2009年08月

    M. Tanaka, H. Sato, Y. Sasaya, S. Horinouchi, J. Hotta, Y. Matsuo, K. Ijiro, K. Sasaki, M. Shimomura

    共著(海外含む)

  • Dynamical Analysis of Triplet Lifetime of Single Molecules by a Photon Interdetection Time Analysis Method(共著),Journal of Physical Chemistry C,113(27) 11652-11656,2009年07月

    T. Chiba, H. Fujiwara, J. Hotta, S. Takeuchi, K. Sasaki

    共著(海外含む)

  • Synthesis, Ensemble, and Single Molecule Characterization of a Diphenyl-Acetylene Linked Perylenediimide Trimer(共著),Journal of Physical Chemistry C,113(27) 11773-11782,2009年07月

    T. Vosch, E. Fron, J. Hotta, A. Deres, H. Uji-i, A. Idrissi, J. Yang, D. Kim, L. Puhl, A. Haeuseler, K. Müllen, F. C. De Schryver, M. Sliwa, J. Hofkens

    共著(海外含む)

  • Defocused Wide-field Imaging Unravels Structural and Temporal Heterogeneity in Complex Systems(共著),Advanced Materials,21(10-11) 1079-1090,2009年03月

    P. Dedecker, B. Muls, A. Deres, H. Uji-i, J. Hotta, M. Sliwa, J-P Soumillion, K. Müllen, J. Enderlein, J. Hofkens

    共著(海外含む)

  • Diffraction-unlimited optical microscopy(共著),Materials Today,11(S1) 12-21,2009年01月

    P. Dedecker, J. Hofkens, J. Hotta

    共著(海外含む)

  • Water-soluble monofunctional perylene and terrylene dyes: Powerful labels for single-enzyme tracking(共著),Angewandte Chemie International Edition,47(18) 3372-3375,2008年03月

    K. Peneva, G. Mihov, F. Nolde, S. Rocha, J. Hotta, K. Braeckmans, J. Hofkens, H. Uji-i, A. Herrmann, K. Müllen

    共著(海外含む)

  • Excitation energy migration processes in cyclic porphyrin Arrays probed by single molecule spectroscopy(共著),Journal of the American Chemical Society,130(6) 1879-1884,2008年02月

    J. Yang, M. Park, Z. S. Yoon, T. Hori, X. Peng, N. Aratani, P. Dedecker, J. Hotta, H. Uji-i, M. Sliwa, J. Hofkens, A. Osuka, D. Kim

    共著(海外含む)

  • Radical polymerization tracked by single molecule spectroscopy(共著),Angewandte Chemie International Edition,47(4) 783-787,2008年01月

    D. Wöll, H. Uji-i, T. Schnitzler, J. Hotta, P. Dedecker, A. Herrmann, F. de Schryver, K. Müllen, J. Hofkens

    共著(海外含む)

  • Subdiffraction imaging through the selective donut-mode depletion of thermally stable photoswitchable fluorophores: Numerical analysis and application to the fluorescent protein Dronpa(共著),Journal of the American Chemical Society,129(51) 16132-16141,2007年12月

    P. Dedecker, J. Hotta, C. Flors, M. Sliwa, H. Uji-i, M. B. J. Roeffaers, R. Ando, H. Mizuno, A. Miyawaki, J. Hofkens

    共著(海外含む)

  • 3D nanoscopy: Bringing biological nanostructures into sharp focus(共著),Angewandte Chemie International Edition,46(44) 8330-8332,2007年11月

    P. Dedecker, C. Flors, J. Hotta, H. Uji-i, J. Hofkens

    共著(海外含む)

  • A stroboscopic approach for fast photoactivation-localization microscopy with Dronpa mutants(共著),Journal of the American Chemical Society,129(45) 13970-13977,2007年10月

    C. Flors, J. Hotta, H. Uji-i, P. Dedecker, R. Ando, H. Mizuno, A. Miyawaki, J. Hofkens

    共著(海外含む)

  • Single perylene diimide dendrimers as single-photon sources(共著),Journal of Physics: Condensed Matter,19(44) 445004,2007年10月

    M. Sliwa, C. Flors, I. Oesterling, J. Hotta, K. Müllen, F. C. De Schryver J. Hofkens

    共著(海外含む)

  • Visualization of membrane rafts using a perylene monoimide derivative and fluorescence lifetime Imaging(共著),Biophysical Journal,93(8) 2877-2891,2007年10月

    A. Margineanu, J. Hotta, R. Vallée, M. Auweraer, M. Ameloot, A. Stefan, D. Beljonne, Y. Engelborghs, A. Herrmann, K. Müllen, F. C. De Schryver, J. Hofkens

    共著(海外含む)

  • Fluorescence of single molecules in polymer films: Sensitivity of blinking to local environment(共著),Journal of Physical Chemistry B,111(25) 6987-6991,2007年06月

    J. N. Clifford, T. D. M. Bell, P. Tinnefeld, M. Heilemann, S. M. Melnikov, J. Hotta, M. Sliwa, P. Dedecker, M. Sauer, J. Hofkens, Y. K. L. Yeow,

    共著(海外含む)

  • Single-molecule spectroscopic investigation of energy migration processes in cyclic porphyrin arrays(共著),Journal of the American Chemical Society,129(12) 3539-3544,2007年03月

    M. Park, M.-C. Yoon, Z. S. Yoon, T. Hori, X. Peng, N. Aratani, J. Hotta, H. Uji-i, M. Sliwa, J. Hofkens, A. Osuka, D. Kim

    共著(海外含む)

  • Orientational effects in the excitation and de-excitation of single molecules interacting with donut-mode laser beams(共著),Optics Express,15(6) 3372-3383,2007年03月

    P. Dedecker, B. Muls, J. Hofkens, J. Enderlein, J. Hotta

    共著(海外含む)

  • Analysis of quantum dot fluorescence coupled with a microsphere resonator(共著),Japanese Journal of Applied Physics. Part. 1, Regular Papers Brief Communications & Review Papers,45(9A) 6917-6921,2006年09月

    H. Takashima, H. Fujiwara, J. Hotta, S. Takeuchi, K. Sasaki, S. Murakami, T. Torimoto, D. Ohtani

    共著(海外含む)

  • The fabrication of a thin, circular polymer film based phase shaper for generating doughnut modes(共著),Optics Express,14(13) 6273-6278,2006年06月

    J. Hotta, H. Uji-i, J. Hofkens

    共著(海外含む)

  • Fast and reversible photoswitching of the fluorescent protein Dronpa as evidenced by fluorescence correlation spectroscopy(共著),Biophysical Journal,91(5) L45-L47,2006年06月

    P. Dedecker, J. Hotta, R. Ando, A.Miyawaki, Y. Engelborghs, J. Hofkens

    共著(海外含む)

  • Photoconversion in the red fluorescent protein from the sea anemone Entacmaea quadricolor: Is cis-trans isomerization involved?(共著),Journal of the American Chemical Society,128(19) 6270-6271,2006年05月

    D. C. Loos, S. Habuchi, C. Flors, J. Hotta, J. R. Wiedenmann, G. U. Nienhaus, J. Hofkens

    共著(海外含む)

  • Photo-induced protonation/deprotonation in the GFP-like fluorescent protein Dronpa: mechanism responsible for the reversible photoswitching,Photochemical & Photobiological Sciences,5(6) 567-576,2006年03月

    S. Habuchi, P. Dedecker, J. Hotta, C. Flors, R. Ando, H. Mizuno, A. Miyawaki, J. Hofkens

    共著(海外含む)

  • Fano resonance in a multimode tapered fiber coupled with a microspherical cavity,APPLIED PHYSICS LETTERS,2005年06月

    A. Chiba, H. Fujiwara, J. Hotta, S. Takeuchi, K. Sasaki

    共著(海外含む)

  • Resonant frequency control of a microspherical cavity by temperature adjustment,JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS,43(9A) 6138-6141,2004年09月

    A. Chiba, H. Fujiwara, J. Hotta, S. Takeuchi, K. Sasaki

    共著(海外含む)

  • Observation of the discrete transition of optically trapped particle position in the vicinity of an interface,APPLIED PHYSICS LETTERS,84(1) 13-15,2004年01月

    H. Fujiwara, H. Takasaki, J. Hotta, K. Sasaki

    共著(海外含む)

  • Jun-ichi Hotta, Hidehisa Takasaki, Hideki Fujiwara, Keiji Sasaki,International Journal of Nanoscience,1(5-6) 645-649,2002年

    Jun-ichi Hotta, Hidehisa Takasaki, Hideki Fujiwara, Keiji Sasaki

    共著(海外含む)

  • Absorption analysis of a single microparticle by optical force measurement,JOURNAL OF APPLIED PHYSICS,2001年05月

    Y. Matsuo, H. Takasaki, J. Hotta, K. Sasaki

    共著(海外含む)

  • Analysis of Radiation Pressure Exerted on a Metallic Particle within an Evanescent Field,OPTICS LETTERS,25(18) 1385-1387,2000年09月

    K. Sasaki, J. Hotta, K. Wada, H. Masuhara

    単著

  • Photon pressure-induced association of nanometer-sized polymer chains in solution,JOURNAL OF PHYSICAL CHEMISTRY B,103 1660-1663,1999年03月

    T. A. Smith, J. Hotta, K. Sasaki, H. Masuhara, Y. Itoh

    共著(海外含む)

  • Laser-controlled assembling of repulsive unimolecular micelles in aqueous solution,JOURNAL OF PHYSICAL CHEMISTRY B,102(40) 7687-7690,1998年10月

    J. Hotta, K. Sasaki, H. Masuhara, Y. Morishima

    共著(海外含む)

  • Chemical and optical mechanism of microparticle formation of poly(N-vinylcarbazole) in N,N-dimethylformamide by photon pressure of a focused near-infrared laser beam,JOURNAL OF PHYSICAL CHEMISTRY B,102(11) 1896-1901,1998年03月

    P. Borowicz , J. Hotta, K. Sasaki, H. Masuhara

    共著(海外含む)

  • Manipulation of liquid crystal textures with a focused near infrared laser beam,APPLIED PHYSICS LETTERS,1997年10月

    J. Hotta, K. Sasaki, H. Masuhara

    共著(海外含む)

  • Laser-controlled association of poly(N-vinylcarbazole) in organic solvents: Radiation pressure effect of a focused near-infrared laser beam,JOURNAL OF PHYSICAL CHEMISTRY B,101(31) 5900-5904,1997年07月

    P. Borowicz, J. Hotta, K. Sasaki, H. Masuhara

    共著(海外含む)

  • Fast and accurate analysis of molecular relaxation processes on high-intensity excitation: non-linear analysis with a convolved autoregressive model,JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,107(1-3) 21-25,1997年07月

    K. Sasaki, J. Hotta, H. Masuhara

    共著(海外含む)

  • Molecular association by the radiation pressure of a focused laser beam: Fluorescence characterization of pyrene-labeled PNIPAM,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,119 (11) 2741-2742,1997年03月

    J. Hofkens, J. Hotta, K. Sasaki, H. Masuhara, T, Taniguchi, T. Miyashita

    共著(海外含む)

  • Molecular assembling by the radiation pressure of a focused laser beam: Poly(N-isopropylacrylamide) in aqueous solution,LANGMUIR,13(3) 414-419,1997年02月

    J. Hofkens, J. Hotta, K. Sasaki, H. Masuhara, K. Iwai

    共著(海外含む)

  • A single droplet formation from swelled micelles by radiation pressure of a focused infrared laser beam,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,118(47) 11968-11969,1996年11月

    J. Hotta, K. Sasaki, H. Masuhara

    共著(海外含む)

  • In situ measurements of ion-exchange processes in single polymer particles: Laser trapping microspectroscopy and confocal fluorescence microspectroscopy,ANALYTICAL CHEMISTRY,68(3) 409-414,1996年02月

    H.-B. Kim, M. Hayashi, K. Nakatani, N. Kitamura, K. Sasaki, J. Hotta, H. Masuhara

    共著(海外含む)

  • Laser induced phase transition in aqueous solutions of hydrophobically modified poly(N-isopropylacrylamide).,MOLECULAR CRYSTALS AND LIQUID CRYSTALS SCIENCE AND TECHNOLOGY SECTION A-MOLECULAR CRYSTALS AND LIQUID CRYSTALS,283 165,1996年

    J. Hofkens, J. Hotta, K. Sasaki, H. Masuhara, H. Faes, and F. C. De Schryver

    共著(海外含む)

  • FLUORESCENCE MAPPING AND PHOTOBLEACHING OF DYE-LABELED LATEX-PARTICLES DISPERSED IN POLY(VINYL ALCOHOL) MATRICES WITH A NEAR-FIELD OPTICAL MICROSCOPE,MACROMOLECULES,28(22) 7530-7535,1995年10月

    M. Rücker, P. Vanoppen, F. C. De Schryver, J. J. Ter Horst, J. Hotta, H. Masuhara

    共著(海外含む)

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総説・解説記事

  • 入門講座 レーザーを用いる分析技術 「超解像蛍光顕微鏡法」,日本分析化学会,ぶんせき,(561) 440-445,2021年09月

    堀田 純一, 羽鳥 晋由

  • 局在化顕微鏡(PALM/STORM),日本工業出版,光アライアンス,30(8) 20-23,2019年08月

    堀内 友貴, 堀田 純一

  • 基礎講座 バイオイメージング 超解像顕微鏡(STED),応用物理学会,応用物理,87(10) 769-773,2018年10月

    堀田純一

科研費(文科省・学振)獲得実績

  • 基盤研究(B),2018年04月 ~ 2021年03月,珪藻ブルームを終焉に導く珪藻細胞群の同調的休眠機構に関する研究

 

担当授業科目

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