Updated on 2023/11/30


OCHI Haruki
Associate Professor
Laboratory Phone number
Laboratory Fax number

Research Areas

  • Life Science / Developmental biology

  • Life Science / Molecular biology

  • Life Science / Genetics

Graduate School

  • Nara Institute of Science and Technology, Graduate School, Division of Biological Science, Molecular biology

    Doctor's Course, 2003.03, Completed

External Career

  • University of Oregon, Researcher, 2003.04 - 2007.12

  • Nara Institute of Science and Technology, Assistant Professor, 2008.01 - 2012.03

  • Nara Institute of Science and Technology, Researcher, 2012.04 - 2013.01

Academic Society Affiliations

  • The Molecular Bioogy Society of Japan

  • Japanese Society of Developmental Biologists

  • International Society of Developmental Biologists

  • Zoological Society of Japan

  • American Society For Cell Biology



  • Regeneration enhancers: A clue to reactivation of developmental genes, Development, Growth & Differentiation, 2020

    Nanoka Suzuki, Haruki Ochi

    Multiple Authorship (Only Japanese)

  • Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken, Scientific Reports , 2019.08

    Yamashita S, Kataoka K, Yamamoto H, Kato T, Hara S, Yamaguchi K, Renard-Guillet C, Katou Y, Shirahige K, Ochi H, Ogino H, Uchida T, Inui M, Takada S, Shigenobu S, Asahara H.

    Multiple Authorship (Only Japanese)

  • Environmental Oxygen Exposure Allows for the Evolution of Interdigital Cell Death in Limb Patterning, Developmental Cell , 2019

    Cordeiro IR, Kabashima K, Ochi H, Munakata K ,Nishimori C, Laslo M, Hanken J, Tanaka M.

    Multiple Authorship (Including Foreigners)

  • Asymmetrically reduced expression of hand1 homeologs involving a single nucleotide substitution in a cis-regulatory element, Developmental Biology , 2017

    Ochi H, Suzuki N, Kawaguchi A, Ogino H

    Multiple Authorship (Only Japanese)

  • cyclin-dependent kinase inhibitors are fragile in Xenopus, Developmental Biology , 2017

    Tanaka T, Ochi H, Takahashi S, Ueno N, Taira M

    Multiple Authorship (Only Japanese)

  • Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis, Developmental Biology, 2017

    Watanabe M, Yasuoka Y, Mawaribuchi S, Kuretani A, Ito M, Kondo M, Ochi H, Ogino H, Fukui M, Taira M, Kinoshita T

    Multiple Authorship (Including Foreigners)

  • Reactivation of larval keratin gene (krt62L) in blastema epithelium during Xenopus froglet limb regeneration, Developmental Biology , 2017

    Satoh A, Mitogawa K, Saito N, Suzuki M, Suzuki KT, Ochi H, Makanae A:

    Multiple Authorship (Including Foreigners)

  • Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of the Xenopus laevis homoeologs six6L and six6S, Developmental Biology, 2017

    3. Ochi H, Kawaguchi A, Tanouchi M, Suzuki N, Kumada T, Iwata Y, Ogino H:

    Multiple Authorship (Only Japanese)

  • Genome evolution in the allotetraploid frog Xenopus laevis, Nature, 2016

    Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, ...

    Multiple Authorship (Including Foreigners)

  • A Novel Cysteine Knot Protein for Enhancing Sperm Motility That Might Facilitate the Evolution of Internal Fertilization in Amphibians, PLoS ONE, 2016

    Yokoe M, Takayama-Watanabe E, Saito Y, Kutsuzawa M, Fujita K, Ochi H, Nakauchi Y, Watanabe A

    Multiple Authorship (Only Japanese)

  • Identification of distal enhancers for Six2 expression in pronephros., International Journal of Developmental Biology, 2015

    Suzuki, S, Hirano, K, Ogino, H, Ochi H

    Single Author

  • Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates., BMC Biol. , 2014

    3. Yajima, H., Suzuki, M., Ochi, H., Ikeda, K., Sato, S., Yamamura, KI., Ogino, H., Ueno, N. and *Kawakami, K.,

    Single Author

  • Transcriptional regulators in the Hippo signaling pathway control organ growth in Xenopus tadpole tail regeneration, Developmental Biology, 2014

    10. Hayashi S, Ochi H, Ogino H, Kawasumia A, Kameid Y, Tamura K, Yokoyama H

    Multiple Authorship (Only Japanese)

  • Evolution of a tissue-specific silencer underlies divergence in the expression of Pax2 and Pax8, Nature Communications, 2012.04

    Ochi, H., Tamai, T., Nagano, H., Kawaguchi, A., Sudou, N. and Ogino, H.

    Single Author

  • Transcription factors involved in lens development from the preplacodal ectoderm, Dev. Biol., 2012.01

    Ogino, H., Ochi, H., Reza, H. M., and Yasuda, K.

    Multiple Authorship (Including Foreigners)

  • Co-expression of the H3K27 demethylases, JMJD3 and UTX, with the H3K27 methylase, EZH2, during Xenopus embryonic development, Int. J. Dev. Biol, 2012.01

    Kawaguchi, A., Ochi, H., Okano, M., Sudou, N. and Ogino, H

    Multiple Authorship (Including Foreigners)

  • Comparative genomics-based identification and analysis of cis-regulatory elements, Xenopus Protocols Post-Genomic Approaches Methods in Molecular Biology, 2012

    Ogino H, Ochi H, Uchiyama C, Louie S, Grainger RM

    Multiple Authorship (Including Foreigners)

  • Different requirement for Wnt/β-catenin signaling in limb regeneration of larval and adult Xenopus, PLoS ONE, 2011.06

    Yokoyama, H., Maruoka, T., Ochi, H., Aruga, A., Ohgo, S., Ogino, H. and Tamura, K.

    Multiple Authorship (Including Foreigners)

  • Photoporation of biomolecules into single cells in living vertebrate embryos induced by a femtosecond laser amplifier, PLoS ONE, 2011.06

    Hosokawa, Y., Ochi, H., Iino, T., Hiraoka, A. and Tanaka, M.

    Multiple Authorship (Including Foreigners)

  • Conserved expression of mouse Six1 in the pre-placodal region (PPR) and identification of an enhancer for the rostral PPR, Dev. Biol, 2010.06

    Sato, S., Ikeda, K., Shioi, G., Ochi, H., Ogino, H., Yajima, H. and Kawakami, K.

    Multiple Authorship (Including Foreigners)

  • Resources and transgenesis techniques for functional genomics in Xenopus, Dev. Growth. Differ., 2009.06

    Ogino, H. and Ochi, H.

    Multiple Authorship (Including Foreigners)

  • Lbx2 regulates formation of myofibrils, BMC Dev. Biol, 2009.06

    Ochi, H. and Westerfield, M.

    Multiple Authorship (Including Foreigners)

  • Hetrochronical shift in Hox-mediated activation of Sonic hedgehog led to the morphological changes during vertebrate fin evolution, PloS ONE, 2009.06

    Sakamoto, K., Onimaru, K., Munakata, K., Suda, N., Tamura, M., Ochi, H. and Tanaka, M

    Multiple Authorship (Including Foreigners)

  • Smarcd3 regulates zebrafish myogenesis onset, J. Biol. Chem., 2008.06

    Ochi, H., Hans, S. and Westerfield, M.

    Multiple Authorship (Including Foreigners)

  • Signaling networks that regulate muscle development: lessons from zebrafish, Dev. Growth. Differ., 2007.06

    Ochi, H. and Westerfield, M.

    Multiple Authorship (Including Foreigners)

  • Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened, Dev. Biol., 2006.06

    Ochi, H., Pearson, B. J., Chuang, P., Hammerschmidt, M. and Westerfield, M.

    Multiple Authorship (Including Foreigners)

  • Temporal expression of L-Maf and RaxL in developing chicken retina are arranged into mosaic pattern, Gene Expr. Patterns., 2004.12

    Ochi, H., Sakagami, K., Ishii, A., Morita, N., Nishiuchi, M., Ogino, H. And Yasuda, K.

    Multiple Authorship (Including Foreigners)

  • The stability of the lens-specific Maf protein is regulated by fibroblast growth factor (FGF)/ERK signaling in lens fiber differentiation, J. Biol. Chem., 2003.01

    Ochi, H., Ogino, H., Kageyama, Y. and Yasuda, K.

    Multiple Authorship (Including Foreigners)

  • Cytochrome P450 1A1 cDNA from freshwater teleost medaka (Oryzias latipes)and induction of mRNA by 3-methylcholanthrene in various organs, Environmental Sciences, 2002.06

    Itakura, T, Mahata, S, Hirano, M, Ochi, H. and Ogino, Y.

    Multiple Authorship (Including Foreigners)

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  • Differential use of paralogous genes via evolution of cis-regulatory elements for divergent expression specificities,, Springer, 2014

    Ochi, H., Kawaguchi, A. and Ogino, H.

  • Methods in Molecular Biology, Xenopus Protocols, 2nd edition: Post-Genomic Approaches, Humana press, 2012.12

    Ogino, H., Ochi, H., Uchiyama, C., Louie, S. and Grainger, R. M.

Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Scientific Research(C),2022.04 - 2025.03

  • Grant-in-Aid for Scientific Research(C),2022.04 - 2023.03

  • Grant-in-Aid for Scientific Research(C),2019.04 - 2022.03

  • Grant-in-Aid for Scientific Research(C),2019.04 - 2022.03

  • Grant-in-Aid for Scientific Research(B),2018.04 - 2020.03

  • Grant-in-Aid for Scientific Research(B),2018.04 - 2020.03

  • Grant-in-Aid for Scientific Research(C),2016.04 - 2019.03

  • Grant-in-Aid for Young Scientists(B),2012.04 -

  • Grant-in-Aid for Young Scientists(B),2008.04 - 2013.03

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Academic Activity

  • Zoological Society of Japan, 2013 - 2014

  • Zoological Society of Japan, 2015 -

  • Zoological Society of Japan, 2018 -

Media Coverage

  • 日本発生学会夏季シンポジウム ,2019.09

Academic Activities

  • 平成30年度 動物学会東北支部大会 (山形大会) 実行委員長,2018.07

  • 第12回ツメガエル研究集会/第4回次世代両生類研究会 実行委員,2018