Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice., Scientific reports, 10(1) 17934, 2020.10

Homma T, Kurahashi T, Ishii N, Shirasawa N, Fujii J

Multiple Authorship (Only Japanese)

Cysteine preservation confers resistance to glutathione-depleted cells against ferroptosis via CDGSH iron sulphur domain-containing proteins (CISDs)., Free Radic Res., 2020.06

Homma T, Kobayashi S, Fujii J.

Multiple Authorship (Only Japanese)

Heterozygous SOD1 deficiency in mice with an NZW background causes male infertility and an aberrant immune phenotype., Free Radic Res, 2019.12

Homma T, Takeda Y, Sakahara S, Ishii N, Kobayashi S, Abe H, Asao H, Fujii J

Multiple Authorship (Only Japanese)

Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro., Experimental cell research, 384(1) 111592, 2019.11

Homma T, Kobayashi S, Sato H, Fujii J

Multiple Authorship (Only Japanese)

Induction of ferroptosis by singlet oxygen generated from naphthalene endoperoxide., Biochemical and biophysical research communications, 518(3) 519-525, 2019.10

Homma T, Kobayashi S, Fujii J

Multiple Authorship (Only Japanese)

An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice., Biochim Biophys Acta Gen Subj, 1863(6) 1108-1115, 2019.06

Homma Takujiro, Fujii Junichi

Multiple Authorship (Only Japanese)

Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury., Toxicol Lett, 294 37-43, 2018.09

Homma Takujiro, Shirato Takaya, Akihara Ryusuke, Kobayashi Sho, Lee Jaeyong, Yamada Ken-Ichi, Miyata Satoshi, Takahashi Motoko, Fujii Junichi

Multiple Authorship (Only Japanese)

Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure., Oxid Med Cell Longev, 2018 2812904, 2018

Homma Takujiro, Kurahashi Toshihiro, Lee Jaeyong, Nabeshima Atsunori, Yamada Sohsuke, Fujii Junichi

Multiple Authorship (Only Japanese)

Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a)., Behav Brain Res, 319 219-224, 2017.02

Homma Takujiro, Akihara Ryusuke, Okano Satoshi, Shichiri Mototada, Yoshida Yasukazu, Yamada Ken-Ichi, Miyata Satoshi, Nakajima Osamu, Fujii Junichi

Multiple Authorship (Only Japanese)

Heat stress promotes the down-regulation of IRE1alpha in cells: An atypical modulation of the UPR pathway., Exp Cell Res, 349(1) 128-138, 2016.11

Homma Takujiro, Fujii Junichi

Multiple Authorship (Only Japanese)

SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes., Arch Biochem Biophys, 583 65-72, 2015.10

Homma Takujiro, Kurahashi Toshihiro, Lee Jaeyong, Kang Eun Sil, Fujii Junichi

Multiple Authorship (Only Japanese)

SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse., Biochem Biophys Res Commun, 463(4) 1040-1046, 2015.08

Homma Takujiro, Okano Satoshi, Lee Jaeyong, Ito Junitsu, Otsuki Noriyuki, Kurahashi Toshihiro, Kang Eun Sil, Nakajima Osamu, Fujii Junichi

Multiple Authorship (Only Japanese)

Ubiquitin-specific protease 14 modulates degradation of cellular prion protein., Sci Rep, 5 11028, 2015.06

Homma Takujiro, Ishibashi Daisuke, Nakagaki Takehiro, Fuse Takayuki, Mori Tsuyoshi, Satoh Katsuya, Atarashi Ryuichiro, Nishida Noriyuki

Multiple Authorship (Only Japanese)

Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs., Curr Drug Metab, 16(7) 560-571, 2015

Homma Takujiro, Fujii Junichi

Multiple Authorship (Only Japanese)

Persistent prion infection disturbs the function of Oct-1, resulting in the down-regulation of murine interferon regulatory factor-3., Sci Rep, 4 6006, 2014.08

Homma Takujiro, Ishibashi Daisuke, Nakagaki Takehiro, Fuse Takayuki, Sano Kazunori, Satoh Katsuya, Atarashi Ryuichiro, Nishida Noriyuki

Multiple Authorship (Only Japanese)

Increased expression of p62/SQSTM1 in prion diseases and its association with pathogenic prion protein., Sci Rep, 4 4504, 2014.03

Homma Takujiro, Ishibashi Daisuke, Nakagaki Takehiro, Satoh Katsuya, Sano Kazunori, Atarashi Ryuichiro, Nishida Noriyuki

Multiple Authorship (Only Japanese)

Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection., Neuroscience research, 171 34-40, 2021.10

Fuse T, Nakagaki T, Homma T, Tange H, Yamaguchi N, Atarashi R, Ishibashi D, Nishida N

Single Author

Carnosine dipeptidase II (CNDP2) protects cells under cysteine insufficiency by hydrolyzing glutathione-related peptides., Free radical biology & medicine, 174 12-27, 2021.10

Kobayashi S, Homma T, Okumura N, Han J, Nagaoka K, Sato H, Konno H, Yamada S, Takao T, Fujii J

Single Author

Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages., Biochemistry and biophysics reports, 26 100942, 2021.07

Kobayashi S, Homma T, Fujii J

Single Author

Pleiotropic Actions of Aldehyde Reductase (AKR1A)., Metabolites, 11(6) , 2021.05

Fujii J, Homma T, Miyata S, Takahashi M

Single Author

Erythrocytes as a preferential target of oxidative stress in blood., Free radical research, 55(5) 562-580, 2021.05

Fujii J, Homma T, Kobayashi S, Warang P, Madkaikar M, Mukherjee MB

Single Author

Developmental retardation in neonates of aldehyde reductase (AKR1A)-deficient mice is associated with low ascorbic acid and high corticosterone levels., The Journal of nutritional biochemistry, 91 108604, 2021.05

Ishii N, Homma T, Takeda Y, Aung NY, Yamada KI, Miyata S, Asao H, Yamakawa M, Fujii J

Single Author

Characterization of a rat monoclonal antibody raised against ferroptotic cells., J Immunol Methods., 2021.02

Kobayashi S, Harada Y, Homma T, Yokoyama C, Fujii J.

Multiple Authorship (Only Japanese)

Ferroptosis caused by cysteine insufficiency and oxidative insult., Free radical research, 54(11-12) 969-980, 2020.12

Fujii J, Homma T, Kobayashi S

Single Author

Ascorbic acid prevents N-nitrosodiethylamine-induced hepatic injury and hepatocarcinogenesis in Akr1a-knockout mice., Toxicology letters, 333 192-201, 2020.10

Ishii N, Homma T, Guo X, Yamada KI, Yamada S, Fujii J

Single Author

Genetic ablation of aldehyde reductase (Akr1a) augments exercise endurance in mice via activation of the PGC-1α-involved pathway., Life sciences, 249 117501, 2020.05

Takahashi M, Homma T, Yamada KI, Miyata S, Nakajima O, Fujii J

Single Author

Prion protein interacts with the metabotropic glutamate receptor 1 and regulates the organization of Ca²⁺ signaling., Biochemical and biophysical research communications, 525(2) 447-454, 2020.04

Matsubara T, Satoh K, Homma T, Nakagaki T, Yamaguchi N, Atarashi R, Sudo Y, Uezono Y, Ishibashi D, Nishida N

Single Author

Ascorbic acid and CoQ10 ameliorate the reproductive ability of superoxide dismutase 1-deficient female mice., Biology of reproduction, 102(1) 102-115, 2020.02

Ishii N, Homma T, Lee J, Mitsuhashi H, Yamada KI, Kimura N, Yamamoto Y, Fujii AJ

Single Author

Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice., J Clin Biochem Nutr., 2019.11

Kurihara K, Homma T, Kobayashi S, Shichiri M, Fujiwara H, Fujii S, Yamada KI, Nakane M, Kawamae K, Fujii J

Multiple Authorship (Only Japanese)

A heterozygous deficiency in protein phosphatase Ppm1b results in an altered ovulation number in mice., Mol Med Rep, 19(6) 5353-5360, 2019.06

Ishii Naoki, Homma Takujiro, Watanabe Ren, Kimura Naoko, Ohnishi Motoko, Kobayashi Takayasu, Fujii Junichi

Multiple Authorship (Only Japanese)

The Association of Peroxiredoxin 4 with the Initiation and Progression of Hepatocellular Carcinoma., Antioxid Redox Signal, 30(10) 1271-1284, 2019.04

Guo Xin, Noguchi Hirotsugu, Ishii Naoki, Homma Takujiro, Hamada Taiji, Hiraki Tsubasa, Zhang Jing, Matsuo Kei, Yokoyama Seiya, Ishibashi Hiroaki, Fukushige Tomoko, Kanekura Takuro, Fujii Junichi, Uram...

Multiple Authorship (Only Japanese)

Type I interferon protects neurons from prions in in vivo models., Brain, 142(4) 1035-1050, 2019.04

Ishibashi Daisuke, Homma Takujiro, Nakagaki Takehiro, Fuse Takayuki, Sano Kazunori, Satoh Katsuya, Mori Tsuyoshi, Atarashi Ryuichiro, Nishida Noriyuki

Multiple Authorship (Only Japanese)

Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice., Free Radic Biol Med, 134 153-164, 2018.12

Takagi Tomohisa, Homma Takujiro, Fujii Junichi, Shirasawa Nobuyuki, Yoriki Hiroyuki, Hotta Yuma, Higashimura Yasuki, Mizushima Katsura, Hirai Yasuko, Katada Kazuhiro, Uchiyama Kazuhiko, Naito Yuji, It...

Multiple Authorship (Only Japanese)

Mutual interaction between oxidative stress and endoplasmic reticulum stress in the pathogenesis of diseases specifically focusing on non-alcoholic fatty liver disease., World J Biol Chem, 9(1) 1-15, 2018.10

Fujii Junichi, Homma Takujiro, Kobayashi Sho, Seo Han Geuk

Multiple Authorship (Including Foreigners)

Unveiling systemic organ disorders associated with impaired lipid catabolism in fasted SOD1-deficient mice., Arch Biochem Biophys, 654 163-171, 2018.09

Lee Jaeyong, Homma Takujiro, Kobayashi Sho, Ishii Naoki, Fujii Junichi

Multiple Authorship (Only Japanese)

Cystine/glutamate transporter, system xc(-), is involved in nitric oxide production in mouse peritoneal macrophages., Nitric Oxide, 78 32-40, 2018.08

Kobayashi Sho, Hamashima Shinji, Homma Takujiro, Sato Mami, Kusumi Ryosuke, Bannai Shiro, Fujii Junichi, Sato Hideyo

Multiple Authorship (Only Japanese)

Potential involvement of ubiquitin-proteasome system dysfunction associated with oxidative stress in the pathogenesis of sickle cell disease., Br J Haematol, 182(4) 559-566, 2018.08

Warang Prashant, Homma Takujiro, Pandya Riddhi, Sawant Anuja, Shinde Nikhil, Pandey Debjeet, Fujii Junichi, Madkaikar Manisha, Mukherjee Malay B

Multiple Authorship (Including Foreigners)

The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production., Exp Cell Res, 361(1) 178-191, 2017.12

Lee Jaeyong, Kang Eun Sil, Kobayashi Sho, Homma Takujiro, Sato Hideyo, Seo Han Geuk, Fujii Junichi

Multiple Authorship (Only Japanese)

Decreased reproductive performance in xCT-knockout male mice., Free Radic Res, 51(9-10) 851-860, 2017.10

Hamashima Shinji, Homma Takujiro, Kobayashi Sho, Ishii Naoki, Kurahashi Toshihiro, Watanabe Ren, Kimura Naoko, Sato Hideyo, Fujii Junichi

Multiple Authorship (Only Japanese)

Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress., Toxicol Lett, 277 92-103, 2017.08

Lee Jaeyong, Homma Takujiro, Fujii Junichi

Multiple Authorship (Only Japanese)

Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis., Arch Toxicol, 91(3) 1319-1333, 2017.03

Shirato Takaya, Homma Takujiro, Lee Jaeyong, Kurahashi Toshihiro, Fujii Junichi

Multiple Authorship (Only Japanese)

A high-fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult., J Nutr Biochem, 40 44-52, 2017.02

Ito Junitsu, Ishii Naoki, Akihara Ryusuke, Lee Jaeyong, Kurahashi Toshihiro, Homma Takujiro, Kawasaki Ryo, Fujii Junichi

Multiple Authorship (Only Japanese)

xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway., Free Radic Res, 51(1) 80-90, 2017.01

Kang Eun Sil, Lee Jaeyong, Homma Takujiro, Kurahashi Toshihiro, Kobayashi Sho, Nabeshima Atsunori, Yamada Sohsuke, Seo Han Geuk, Miyata Satoshi, Sato Hideyo, Fujii Junichi

Multiple Authorship (Including Foreigners)

Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress., Biochem Biophys Res Commun, 478(2) 765-771, 2016.09

Akihara Ryusuke, Homma Takujiro, Lee Jaeyong, Yamada Ken-Ichi, Miyata Satoshi, Fujii Junichi

Multiple Authorship (Only Japanese)

Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy., Arch Biochem Biophys, 604 36-46, 2016.08

Kurahashi Toshihiro, Lee Jaeyong, Nabeshima Atsunori, Homma Takujiro, Kang Eun Sil, Saito Yuka, Yamada Sohsuke, Nakayama Toshiyuki, Yamada Ken-Ichi, Miyata Satoshi, Fujii Junichi

Multiple Authorship (Only Japanese)

Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase., Regul Toxicol Pharmacol, 79 83-90, 2016.08

Otsuki Noriyuki, Homma Takujiro, Fujiwara Hiroki, Kaneko Kenya, Hozumi Yasukazu, Shichiri Mototada, Takashima Mizuki, Ito Junitsu, Konno Tasuku, Kurahashi Toshihiro, Yoshida Yasukazu, Goto Kaoru, Fuji...

Multiple Authorship (Including Foreigners)

The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice., Free Radic Res, 50(7) 793-800, 2016.07

Otsuki Noriyuki, Konno Tasuku, Kurahashi Toshihiro, Suzuki Saori, Lee Jaeyong, Okada Futoshi, Iuchi Yoshihito, Homma Takujiro, Fujii Junichi

Multiple Authorship (Including Foreigners)

An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy., Biochem Biophys Res Commun, 467(4) 866-871, 2015.11

Kurahashi Toshihiro, Hamashima Shinji, Shirato Takaya, Lee Jaeyong, Homma Takujiro, Kang Eun Sil, Fujii Junichi

Multiple Authorship (Including Foreigners)

Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis., Biochem Biophys Res Commun, 464(1) 229-235, 2015.08

Lee Jaeyong, Homma Takujiro, Kurahashi Toshihiro, Kang Eun Sil, Fujii Junichi

Multiple Authorship (Only Japanese)

Physiological and pathological views of peroxiredoxin 4., Free Radic Biol Med, 83 373-379, 2015.06

Fujii Junichi, Ikeda Yoshitaka, Kurahashi Toshihiro, Homma Takujiro

Multiple Authorship (Only Japanese)

Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus., World J Nephrol, 4(2) 213-222, 2015.05

Fujii Junichi, Kurahashi Toshihiro, Konno Tasuku, Homma Takujiro, Iuchi Yoshihito

Multiple Authorship (Only Japanese)

Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function., J Biol Chem, 290(14) 8778-8788, 2015.04

Kobayashi Sho, Sato Mami, Kasakoshi Takayuki, Tsutsui Takumi, Sugimoto Masahiro, Osaki Mitsuhiko, Okada Futoshi, Igarashi Kiharu, Hiratake Jun, Homma Takujiro, Conrad Marcus, Fujii Junichi, Soga Tomoy...

Multiple Authorship (Including Foreigners)

Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells., PLoS One, 10(9) e0137958, 2015

Ishibashi Daisuke, Homma Takujiro, Nakagaki Takehiro, Fuse Takayuki, Sano Kazunori, Takatsuki Hanae, Atarashi Ryuichiro, Nishida Noriyuki

Multiple Authorship (Only Japanese)

Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals., Biochem Biophys Res Commun, 452(1) 136-141, 2014.09

Kurahashi Toshihiro, Kwon Myoungsu, Homma Takujiro, Saito Yuka, Lee Jaeyong, Takahashi Motoko, Yamada Ken-Ichi, Miyata Satoshi, Fujii Junichi

Multiple Authorship (Only Japanese)

Involvement of purinergic signaling in cellular response to gamma radiation., Radiat Res, 173(3) 298-309, 2010.03

Tsukimoto Mitsutoshi, Homma Takujiro, Ohshima Yasuhiro, Kojima Shuji

Multiple Authorship (Only Japanese)

Low-dose gamma-ray irradiation induces translocation of Nrf2 into nuclear in mouse macrophage RAW264.7 cells., J Radiat Res, 51(3) 349-353, 2010

Tsukimoto Mitsutoshi, Tamaishi Nana, Homma Takujiro, Kojima Shuji

Multiple Authorship (Only Japanese)

0.5 Gy gamma radiation suppresses production of TNF-alpha through up-regulation of MKP-1 in mouse macrophage RAW264.7 cells., Radiat Res, 171(2) 219-224, 2009.02

Tsukimoto Mitsutoshi, Homma Takujiro, Mutou Yasuko, Kojima Shuji

Multiple Authorship (Only Japanese)