Updated on 2023/11/30

写真a

 
TOBAI Tomomi
 
Title
Lecturer
Laboratory Phone number
+81-23-628-5316
 
Laboratory Fax number
+81-23-628-5318
 

Research Areas

  • Life Science / Hematology and medical oncology

External Career

  • , Medical Staff, 1999.05 - 2001.03

  • , Medical Staff, 2001.04 - 2002.03

  • , Graduate student(doctorate program), 2002.04 - 2006.03

  • , Medical Staff, 2006.04 - 2006.10

  • University of Michigan Medical School, Researcher, 2006.11 - 2011.10

  • University of Michigan Medical School, 2011.11 - 2014.02

  • Medical University of South Carolina, Associate Professor (as old post name), 2014.03 - 2014.08

  • University of Michigan Medical School, 2014.08 - 2017.03

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Papers

  • Two-year remission of a relapsed primary gastric peripheral T-cell lymphoma treated with total gastrectomy followed by adjuvant chemotherapy, Rinsho Ketsueki, 62(2) 79-84, 2021

    YANAGIYA Ryo, ISHIZAWA Kenichi, TOUBAI Tomomi, KABASAWA Takanobu, KAMIO Yukinori, SAKURAI Mina, YAMADA Akane, AIZAWA Keiko, ITO Satoshi, OHE Rintaro

    Single Author

  • SNARE protein SEC22B regulates early embryonic development., Scientific Reports, 2019.08

    Wu SJ, Khoriaty R, Kim SH, O'Shea KS, Zhu G, Hoenerhoff M, Zajac C, Oravecz-Wilson K, Toubai T, Sun Y, Ginsburg D, Reddy P.

    Multiple Authorship (Including Foreigners)

  • Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition., Nature Microbiology, 2019.05

    Toubai T, Fujiwara H, Rossi C, Riwes M, Tamaki H, Zajac C, Liu C, Mathew AV, Byun J, Oravecz-Wilson K, Matsuda I, Sun Y, Peltier D, Wu J, Chen J, Seregin S, Henig I, Kim S, Brabbs S, Pennathur S, Chen...

    Multiple Authorship (Including Foreigners)

  • Differential expression of estrogen receptor-α on follicular dendritic cells from patients with grade 1-2 and grade 3 follicular lymphoma., Hematological Oncology, 2019.04

    Ohe R, Meng HX, Ye Aung N, Yamada A, Kabasawa T, Utsunomiya A, Tamazawa N, Tamura Y, Kitaoka T, Hashimoto T, Shibata K, Toubai T, Kimura W, Ishizawa K, Yamakawa M.

    Multiple Authorship (Including Foreigners)

  • Immune-mediated neuropathy with anti-ganglioside antibodies in diffuse large B-cell lymphoma, Rinsho Ketsueki, 60(7) 761-766, 2019

    YANAGIYA Ryo, ISHIZAWA Ken'ichi, ITO Satoshi, YAMADA Akane, AIZAWA Keiko, SHIONO Yosuke, INOKURA Kyoko, TOUBAI Tomomi, KATO Yuichi, HONDA Kouichi

    Single Author

  • Mitochondrial Deacetylase SIRT3 Plays an Important Role in Donor T Cell Responses after Experimental Allogeneic Hematopoietic Transplantation. , The Journal of Immunology, 2018.12

    Toubai T, Tamaki H, Peltier DC, Rossi C, Oravecz-Wilson K, Liu C, Zajac C, Wu J, Sun Y, Fujiwara H, Henig I, Kim S, Lombard DB, Reddy P.

    Multiple Authorship (Including Foreigners)

  • Microbial metabolite sensor GPR43 controls severity of experimental GVHD. , Nature Communications, 2018.09

    Fujiwara H, Docampo MD, Riwes M, Peltier D, Toubai T, Henig I, Wu SJ, Kim S, Taylor A, Brabbs S, Liu C, Zajac C, Oravecz-Wilson K, Sun Y, Núñez G, Levine JE, van den Brink MRM, Ferrara JLM, Reddy P.

    Multiple Authorship (Including Foreigners)

  • Murine Models of Steroid Refractory Graft-versus-Host Disease., Scientific Reports, 2018.08

    Toubai T, Rossi C, Tawara I, Liu C, Zajac C, Oravecz-Wilson K, Peltier D, Sun Y, Fujiwara H, Wu SR, Riwes M, Henig I, Kim S, Reddy P.

    Multiple Authorship (Including Foreigners)

  • Detection of Minimal Bone Marrow involvement of Blastic Plasmacytoid Dendritic Cell Neoplastic Cells - CD303 immunostaining as a diagnostic tool., Journal of Clinical and Experimental Hematopathology, 2018.03

    Ohe R, Aung NY, Shiono Y, Utsunomiya A, Kabasawa T, Tamazawa N, Tamura Y, Kato T, Yamada A, Hasegawa S, Aizawa K, Inokura K, Ito S, Toubai T, Kato Y, Tsunoda T, Onami K, Suzuki T, Ishizawa K, Yamakawa...

    Multiple Authorship (Only Japanese)

  • IAPs protect host target tissues from graft-versus-host disease in mice. , Blood Advances, 2017.08

    Toubai T, Rossi C, Oravecz-Wilson K, Liu C, Zajac C, Wu J, Sun Y, Fujiwara H, Tamaki H, Peltier D, Riwes M, Henig I, Brabbs S, Duckett C, Wang S, Reddy P.

    Multiple Authorship (Including Foreigners)

  • Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells. , Journal of innate immunity, 2017

    Sun, Y., Iyer, M., McEachin, R., Zhao, M., Wu, Y.M., Cao, X., Oravecz-Wilson, K., Zajac, C., Mathewson, N., Wu, S.J., Rossi, C., Toubai, T., Qin, Z.S., Chinnaiyan, A.M., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation. , Cell Reports, 2017

    Wu, S.J., Niknafs, Y.S., Kim, S.H., Oravecz-Wilson, K., Zajac, C., Toubai, T., Sun, Y., Prasad, J., Peltier, D., Fujiwara, H., Hedig, I., Mathewson, N.D., Khoriaty, R., Ginsburg, D., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • STAT3 Expression in Host Myeloid Cells Controls GVHD Severity. , Biology of Blood and Marrow Transplantation, 2017

    Nieves, E.C., Toubai, T., Peltier, D.C., Oravecz-Wilson, K., Liu, C., Tamaki, H., Sun, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Siglec-G represses DAMP mediated effects on T cells. , JCI Insight, 2017

    Toubai, T., Rossi, C., Oravecz-Wilson, K., Zajac, C., Liu, C., Fujiwara, H., Wu, J., Sun, Y., Brabbs, S., Tamaki, H., Magenau, J., Zheng, P., Liu, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Unbiased profiling uncovers a crucial role for targeted gut microbiome derived metabolites in modulating GI epithelial cell damage and mitigating GVHD. , Nature Immunology, 2016

    Mathewson, N., Jenq, R., Mathew, A., Koenigsknecht, M., Hanash, A., Toubai, T., Oravecz-Wilson, K., Wu, S.R., Sun, Y., Rossi, C., Fujiwara, H., Byun, J., Shono, Y., Lindemans, C., Calafiore, M., Schmi...

    Multiple Authorship (Including Foreigners)

  • SAG/Rbx2 dependent neddylation regulates T cell responses. , American Journal of Pathology, 2016

    Mathewson, N., Fujiwara, H., Wu, J., Toubai, T., Oravecz-Wilson, K., Sun, Y., Rossi, C., Zajac, C., Sun, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Host CD8α+Dendritic Cells may be a Key Factor for Separating Graft-versus-Host Disease from Graft-versus-Leukemia., Biology of Blood and Marrow Transplantation, 2015

    Toubai, T., Mathewson, N., Oravecz-Wilson, K., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice., Blood, 2015

    Sun, Y., Wang, Y., Toubai, T., Oravecz-Wilson, K., Liu, C., Mathewson, N., Wu, J., Rossi, C., Cummings, E,, Wu, D., Wang, S., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Mature T cell responses are controlled by microRNA-142. , Journal of Clinical Investigation, 2015

    Sun, Y., Oravecz-Wilson, K., Mathewson, N., Wang, Y., McEachin, R., Liu, C., Toubai, T., Wu, J., Rossi, C., Braun, T., Saunders, T., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Ikaros deficiency in host hematopoietic cells separates GVL from GVHD after experimental allogeneic hematopoietic cell transplantation., OncoImmunology, 2015

    Toubai,T., Hou, G., Rossi, C., Mathewson, N., Oravecz-Wilson, K., Cummings, E., Wu, J., Sun, Y., Choi, S., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Risk factors and organ involvement of chronic graft-versus-host disease in Japan. , Bone Marrow Transplantation, 2014

    39. Kanda, J., Nakasone, H., Atsuta, Y., Toubai, T., Yokoyama, H., Fukuda, T., Taniguchi, S., Ohashi, K., Ogawa, H., Eto, T., Miyamura, K., Morishima, Y., Nagamura-Inoue, T., Sakamaki, H., Murata, M. ...

    Multiple Authorship (Including Foreigners)

  • Aging is Associated with Increased Regulatory T-cell Function., Aging Cell, 2014

    40. Garg, S.K., Delaney, C., Toubai, T., Ghosh, A., Reddy, P., Ruma Banerjee, R., Yung, R.

    Multiple Authorship (Including Foreigners)

  • Siglec-G-CD24 axis controls the severity experimental graft-versus-host disease. , Blood, 2014

    41. Toubai, T., Hou, G., Mathewson, N., Liu, C., Wang, Y., Oravecz-Wilson, K., Sun, Y., Choi, S.W., Fang, D., Zheng, P., Liu, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Genome-wide Ago-CLIP-ChIP analysis identifies novel molecular regulators of allogeneic T cell responses., Journal of Clinical Investigation, 2013

    38. Sun, Y., Tawara, I., Zhao, M., Qin, Z., Toubai, T., Mathewson, N., Tamaki, H., Nieves, E., Chinnaiyan, A., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Influence of donor microbiota on the severity of experimental graft-versus-host-disease. , Biology of Blood and Marrow Transplantation, 2013

    33. Tawara, I., Liu, C., Tamaki, H., Toubai, T., Sun, Y., Evers, R., Nieves, E., Mathewson, N., Nunez, G., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Neddylation plays an important role in the regulation of murine and human dendritic cell function. , Blood, 2013

    37. Mathewson, N., Toubai, T., Kapeles, S., Sun, Y., Oravecz-Wilson, K., Tamaki, H., Wang, Y., Hou, G., Sun, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • T cell-specific Notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells. , Journal of Immunology, 2013

    36. Sandy, A.R., Chung, J., Toubai, T., Shan, G.T., Tran, I.T., Friedman, A., Blackwell, T.S., Reddy, P., King, P.D., Maillard, I.

    Multiple Authorship (Including Foreigners)

  • Host derived CD8+ dendritic cells are required for induction of optimal graft-versus-tumor responses after experimental allogeneic bone marrow transplantation. , Blood, 2013

    35. Toubai, T., Sun, Y., Luker, G., Liu, J., Luker, K.E., Tawara, I., Evers, R., Liu, C., Mathewson, N., Malter, C., Nieves, E., Choi, S., Murphy, K.M., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • PU.1-dependent transcriptional regulation of miR-142 contributes to its hematopoietic cell-specific expression and modulation of IL-6. , Journal of Immunology, 2013

    34. Sun, Y., Sun, J., Toubai, T., Nieves, E., Mathewson, N., Tamaki, H., Evers, R., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Induction of acute graft-versus-host disease by sex-mismatched H-Y antigens in the absence of functional radio-sensitive host hematopoietic-derived antigen presenting cells. , Blood, 2012

    30. Toubai, T., Tawara, I., Sun, Y., Liu, C., Nieves, E., Evers, R., Friedman, T.M., Korngold, R., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Donor but not Host Derived Interleukin-10 Contributes to the Regulation of Experimental Graft-versus-Host Disease., Journal of Leukocyte Biology, 2012

    32. Tawara, I., Sun, Y., Liu, C., Toubai, T., Nieves, E., Evers, R., Alrubaie, M., Mathewson, N., Tamaki, H., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. , Proceedings of the Natural Academy of Sciences of the United States of America , 2012

    31. Tawara, I., Sun, Y., Lewis, E.C., Toubai, T., Evers, R., Nieves, E., Azam, T., Dinarello, C.A., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation. , Clinical Cancer Research, 2011

    26. Tawara, I., Koyama, M., Liu, C., Toubai, T., Thomas, D., Evers, R., Chockley, P., Nieves, E., Sun, Y., Lowler, K.P., Malter, C., Nishimoto, N., Hill, G.R., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Host Basophils are Dispensable for Induction of Donor Th2 Differentiation and Severity of Experimental Graft-versus-Host Disease., Biology of Blood and Marrow Transplantation, 2011

    29. Tawara, I., Nieves, E., Liu, C., Evers, R., Toubai, T., Sun, Y., Alrubaie, M., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Targeting of microRNA-142-3p in dendritic cells regulates endotoxin induced mortality. , Blood, 2011

    28. Sun,Y., Varambally, S., Maher, C.A., Cao, Q., Chockley, P., Toubai, T., Malter, C., Nieves, E., Tawara, I., Wang, Y., Ward, P.A., Chinnaiyan, A., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease. , Blood, 2011

    27. Toubai, T., Sun, Y., Tawara, I., Friedman, A., Liu, C., Evers, R., Nieves, E., Malter, C., Chockley, P., Maillard, I., Winandy, S., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Immunization with host-type CD8{alpha}+ dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner. , Blood, 2010

    24. Toubai, T., Malter, C., Tawara, I., Liu, C., Nieves, E., Lowler, K.P., Sun, Y., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • A crucial role for host APCs in the induction of donor CD4+CD25+ regulatory T cell-mediated suppression of experimental graft-versus-host disease. , Journal of Immunology, 2010

    25. Tawara, I., Shlomchik, W.D., Jones, A., Zou, W., Nieves, E., Liu, C., Toubai, T., Duran-Struuck, R., Sun, Y., Clouthier, S.G., Evers, R., Lowler, K.P., Levy, R.B., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Serum macrophage migration inhibitory factor (MIF) levels after allogeneic hematopoietic stem cell transplantation., International journal of Laboratory Hematology, 2009

    17. Toubai, T., Shono, Y., Nishihira, J., Ibata, M., Suigita, J., Kato, N., Ohkawara, T., Tone, S., Lowler, K.P., Ota, S., Tanaka, J., Asaka, M., Reddy, P., Imamura, M

    Multiple Authorship (Including Foreigners)

  • Serum soluble tumor necrosis factor-related apoptosis-inducing ligand level after allogeneic hematopoietic cell transplantation., Leukemia and Lymphoma, 2009

    23. Toubai, T., Shono, Y., Tone, S., Ibata, M., Kato, N., Malter, C., Lowler, K.P., Ota, S., Tanaka, J., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. , Journal of Immunology, 2009

    22. Sun, Y., Chin, Y.E., Weisiger, E., Malter, C., Tawara, I., Toubai, T., Gatza, E., Mascagni, P., Dinarello, C.A., Reddy, P

    Multiple Authorship (Including Foreigners)

  • Chimerism and T-cell receptor repertoire analysis after unrelated cord blood transplantation with a reduced-intensity conditioning regimen following autologous stem cell transplantation for multiple myeloma. , International Journal of Laboratory Hematology, 2008

    Toubai, T., Hirate, D., Shono, Y., Ota, S., Ibata, M., Mashiko, S., Sugita, J., Shigematsu, A., Miura, Y., Kato, N., Umehara, S., Kahata, K., Tsutsumi, Y., Iwao, N., Toyoshima, N., Tanaka, J., Asaka, ...

    Multiple Authorship (Including Foreigners)

  • Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprca mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies., Journal of Translational Medicine , 2008

    18. Duran-Struuck, R., Hartigan, A., Clouthier, S.G.., Dyson, M.C., Lowler, K., Gatza, E., Tawara, I., Toubai, T., Weisiger, E., Hugunin, K., Reddy, P., Wilkinson, J.E.

    Multiple Authorship (Including Foreigners)

  • T cell receptor excision circle levels in CD94-expressing CD8 T Cells during graft-versus-host disease. , Leukemia and Lymphoma, 2008

    21. Sugita, J., Iwao, N., Tanaka, J., Kato, N., Shiratori, S., Wakasa, K., Shigematsu, A., Toubai, T., Takahata, M., Kondo, T., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. , Journal of Clinical Investigation, 2008

    20. Reddy, P., Sun, Y., Toubai, T., Duran-Struuck, R., Clouthier, S.G., Weisiger, E., Maeda, Y., Tawara, I., Krijanovski, O., Gatza, E., Liu, C., Malter, C., Mascagni, P., Dinarello, C.A., Ferrara, J....

    Multiple Authorship (Including Foreigners)

  • Combined Th2 cytokine deficiency in donor T cells aggravates experimental acute graft-vs-host disease. , Experimental Hematology, 2008

    19. Tawara, I., Maeda, Y., Sun, Y., Lowler, K.P., Liu, C., Toubai, T., McKenzie, A.N., Reddy, P.

    Multiple Authorship (Including Foreigners)

  • Efficacy and safety of micafungin in febrile neutropenic patients treated for hematological malignancies. , Internal Medicine, 2007

    14. Toubai, T., Tanaka, J., Ota, S., Shigematsu, A., Shono, Y., Ibata, M., Hashino, S., Kondo, T., Kakinoki, Y., Masauzi, N., Kasai, M., Iwasaki, H., Kurosawa, M., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Expansion of natural killer cell receptor (CD94/NKG2A)-expressing cytolytic CD8 T cells and CD4(+)CD25(+) regulatory T cells from the same cord blood unit. , Experimental Hematology, 2007

    16. Tanaka, J., Sugita, J., Kato, N., Toubai, T., Ibata, M., Shono, Y., Ota, S., Kondo, T., Kobayashi, T., Kobayashi, M., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells., Leukemia, 2007

    15. Kato, N., Tanaka, J., Sugita, J., Toubai, T., Miura, Y., Ibata, M., Syono, Y., Ota, S., Kondo, T., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Abnormal expansion of naive B lymphocytes after unrelated cord blood transplantation-a case report. , Clinical & Laboratory Hematology, 2006

    Shono, Y., Toubai, T., Ota, S., Ibata, M., Mashiko, S., Hirate, D., Miura, Y., Umehara, S., Toyoshima, N., Tanaka, J., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Analysis of donor-type chimerism in lineage-specific cell populations after allogeneic myeloablative and non-myeloablative stem cell transplantation., Bone Marrow Transplantation, 2006

    10. Miura, Y., Tanaka, J., Toubai, T., Tsutsumi, Y., Kato, N., Hirate, D., Kaji, M., Sugita, J., Shigematsu, A., Iwao, N., Ota, S., Masauzi, N., Fukuhara, T., Kasai, M., Asaka, M., Imamura, M

    Multiple Authorship (Including Foreigners)

  • Effect of granulocyte colony-stimulating factor on IL-12 p40 production during chemotherapy for B-cell lineage non-Hodgkin's lymphoma patients. , European Journal of Haematology, 2006

    13. Toubai, T., Tanaka, J., Ota, S., Fukuhara, T., Hashino, S., Kondo, T., Shono, Y., Morioka, M., Kawamura, T., Masauzi, N., Kakinoki, Y., Kobayashi, H., Kunieda, Y., Kasai, M., Kurosawa, M., Asaka, ...

    Multiple Authorship (Including Foreigners)

  • Effect of macrophage migration inhibitory factor (MIF) on acute graft-versus-host disease in a murine model of allogeneic stem cell transplantation., Transplant Immunology, 2006

    12. Toubai, T., Tanaka, J., Nishihira, J., Ohkawara, T., Hirate, D., Kondo, N., Tone, S., Shono, Y., Iwao, N., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Effect of imatinib mesylate combined with granulocyte colony-stimulating factor on leukaemic blast cells derived from advanced-stage chronic myelogenous leukaemia patients., Acta Haematologica, 2006

    11. Ota, S., Musashi, M., Kondo, K., Toyoshima, N., Toubai, T., Onozawa, M., Mori, A., Hashino, S., Tanaka, J., Matsuno, K., Imamura, M., Asaka, M.

    Multiple Authorship (Including Foreigners)

  • 造血器悪性腫瘍患者の好中球減少時におけるイトラコナゾールカプセル剤200mg/日投与の真菌感染症の予防効果., The Japanese journal of antibiotics , 2005

    東梅友美, 田中淳司, 太田秀一, 加藤菜穂子, 梅原伸太郎, 加畑馨, 豊島經康, 浅香正博, 今村雅寛

    Multiple Authorship (Including Foreigners)

  • t(1:3)(q10;p10) and chromosome 7 abnormality associated with the progression of multiple myeloma. , Clinical & Laboratory Hematology, 2005

    Toubai, T., Tanaka, J., Higa, T., Iwao, N., Shigematsu, A., Kato, N., Watanabe, K., Sudo, J., Kasai, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Long-term follow-up of a patient with idiopathic myelofibrosis associated with chromosome 11 and 13 abnormalities. , American Journal of Hematology, 2005

    Toubai, T., Tanaka, J., Higa, T., Ota, S., Ibata, M., Shono, Y., Mashiko, S., Miura, Y., Umehara, S., Kahata, K., Toyoshima, N., Morioka, M., Asaka, M., Kasai, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Successful reduced-intensity stem cell transplantation (RIST) for a patient with malignant lymphoma and an ileostomy., Internal Medicine, 2005

    Toubai, T., Tanaka, J., Ota, S., Mori, A., Ibata, M., Shono, Y., Mashiko, S., Sugita, J., Miura, Y., Kato, N., Umehara, S., Kahata, K., Toyoshima, N., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Cytolytic activity and regulatory functions of inhibitory NK cell receptor-expressing T cells expanded from granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells. , Blood, 2005

    2. Tanaka, J., Toubai, T., Tsutsumi, Y., Miura, Y., Kato, N., Umehara, S., Kahata, K., Mori, A., Toyoshima, N., Ota, S., Kobayashi, T., Kobayashi, M., Kasai, M., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • The immunosuppressive agent FK506 enhances the cytolytic activity of inhibitory natural killer cell receptor (CD94/NKG2A)-expressing CD8 T cells. , Transplantation, 2005

    9. Tanaka, J., Toubai, T., Iwao, N., Tsutsumi, Y., Kato, N., Miura, Y., Shigematsu, A., Hirate, D., Ota, S., Asaka, M., Imamura M.

    Multiple Authorship (Including Foreigners)

  • Minimal residual disease (MRD) monitoring using rearrangement of T-cell receptor and immunoglobulin H gene in the treatment of adult acute lymphoblastic leukemia patients. , American Journal of Hematology, 2005

    8. Toubai, T., Tanaka, J., Ota, S., Fukuhara, T., Hashino, S., Kondo, T., Kasai, M., Kakinoki, Y., Masauzi, N., Morioka, M., Kawamura, T., Iwasaki, H., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Progressive disappearance of anti-hepatitis B surface antigen antibody and reverse seroconversion after allogeneic hematopoietic stem cell transplantation in patients with previous hepatitis B virus infection., Transplantation, 2005

    7. Onozawa, M., Hashino, S., Izumiyama, K., Kahata, K., Chuma, M., Mori, A., Kondo, T., Toyoshima, N., Ota, S., Kobayashi, S., Hige, S., Toubai, T., Tanaka, J., Imamura, M., Asaka, M

    Multiple Authorship (Including Foreigners)

  • Cytolytic activity against primary leukemic cells by inhibitory NK cell receptor (CD94/NKG2A)-expressing T cells expanded from various sources of blood mononuclear cells., Leukemia, 2005

    6. Tanaka, J., Iwao, N., Toubai, T., Tsutsumi, Y., Miura, Y., Kato, N., Shigematsu, A., Yamane, M., Ota, S., Kondo, T., Kobayashi, T., Takeda, H., Kobayashi, M., Asaka, M., Imamura, M

    Multiple Authorship (Including Foreigners)

  • A case report of primary gastric adult T cell lymphoma., Nihon Ronen Igakkai Zasshi, 2004

    Multiple Authorship (Only Japanese)

  • Successful micafungin (FK463) treatment of invasive pulmonary aspergillosis in a patient with acute lymphoblastic leukemia in a phase II study. , International Journal of Hematology, 2004

    Ota, S., Tanaka, J., Kahata, K., Toubai, T., Kondo, K., Mori, A., Toyoshima, N., Musashi, M., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Allogeneic bone marrow transplantation from an unrelated donor for the treatment of chronic myelogenous leukemia in blast crisis in a patient with Kleinfelter's syndrome. , Leukemia & Lymphoma, 2004

    Toubai, T., Tanaka, J., Ota, S., Miura, Y., Toyoshima, N., Asaka, M., Imamura, M

    Multiple Authorship (Including Foreigners)

  • Mediastinal emphysema and bilateral pneumothoraces with chronic GVHD in patients after allogeneic stem cell transplantation., Bone Marrow Transplantation, 2004

    1. Toubai, T., Tanaka, J., Kobayashi, N., Honda, T., Miura, Y., Ogawa, T., Imai, K., Ogasawara, M., Kiyama, Y., Higa, T., Imamura, M., Kasai, M.

    Multiple Authorship (Including Foreigners)

  • Differential expression of natural killer cell receptors (CD94/NKG2A) on T cells by the stimulation of G-CSF-mobilized peripheral blood mononuclear cells with anti-CD3 monoclonal antibody and cytokines: a study in stem cell donors., Transplantation Proceedings, 2004

    5. Tanaka, J., Toubai, T., Miura, Y., Tsutsumi, Y., Kato, N., Umehara, S., Toyoshima, N., Ohta, S., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Efficacy of etoposide, cyclophosphamide, and total body irradiation in allogeneic bone marrow transplantation for adult patients with hematological malignancies. , Clinical Transplantation, 2004

    4. Toubai, T., Tanaka, J., Mori, A., Hashino, S., Kobayashi, S., Ota, S., Miura, Y., Kato, N., Kahata, K., Izumiyama, K., Yonezumi, M., Chiba, K., Kondo, T., Toyoshima, N., Asaka, M., Imamura, M.

    Multiple Authorship (Including Foreigners)

  • Molecular analysis of T-cell repertoire in patients with graft-versus-host disease after allogeneic stem cell transplantation., Leukemia and Lymphoma, 2004

    3. Tsutsumi, Y., Tanaka, J., Miura, Y., Toubai, T., Kato, N., Fujisaw, F., Toyoshima, N., Ota, S., Mori, A., Yonezumi, M., Chiba, K., Kondo, T., Hasino, S., Kobayasi, R., Masauji, N., Kasai, M., Asaka...

    Multiple Authorship (Including Foreigners)

  • Evaluation of bone marrow involvement by FDG-PET for refractory Hodgkin lymphoma treated by unrelated allogeneic bone marrow transplantation., `Rinsho Ketsueki, 2003

    Multiple Authorship (Only Japanese)

  • Effect of prophylaxis against myocosis in patients with hematological malignancy disease: efficacy of dosage of itraconazole., 2003

    Multiple Authorship (Only Japanese)

  • A case of leukemia of the appendix presenting as acute appendicitis., Acta Haematologica, 2003

    Toubai, T., Kondo, Y., Ogawa, Y., Imai, A., Kobayashi, N., Ogasawara, M., Kiyama, Y., Higa, T., Sato, K., Miyokawa, N., Tanaka J., Imamura, M., Kasai, K.

    Multiple Authorship (Including Foreigners)

  • Primary adrenal lymphoma: a case report and literature review in Japan., Rinsho Ketsueki, 2002

    Multiple Authorship (Only Japanese)

  • Fever of unknown origin due to sclerosing mediastinitis., Nihon Naika Gakkai Zasshi, 2001

    Multiple Authorship (Only Japanese)

  • Purpura due to vasculitis induced by interferon therapy for a patient with chronic hepatitis type C., Nihon Naika Gakkai Zasshi., 2001

    Multiple Authorship (Only Japanese)

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Review Papers

  • Danger signals and graft-versus-host disease: Current understanding and future perspectives., Frontiers in Immunology, 2016

    Toubai T, Mathewson ND, Magenau J, Reddy P.

  • Role of cytokines in the pathophysiology of acute graft-versus-host disease (GVHD) – Are serum/plasma cytokines potential biomarkers for diagnosis of acute GVHD following allogeneic hematopoietic cell transplantation (allo-HCT)? , Current Stem Cell Research & Therapy, 2012

    Toubai, T., Tanaka, J., Paczesny, S., Shono, Y., Reddy, P., Imamura, M.

  • Mesenchymal stem cells for treatment and prevention of graft-versus-host disease after allogeneic hematopoietic cell transplantation, Current Stem Cell Research & Therapy, 2009

    Toubai, T., Paczesny, S., Shono, Y., Tanaka, J., Lowler, K.P., Malter, C.T., Kasai, M., Imamura, M.

  • Immue reconstitution and tolerance after allogeneic hematopoietic stem cell transplantation, Hematology, 2003

    Imamura, M., Tsutsumi, Y., Miura, Y., Toubai T., Tanaka, J.

Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Scientific Research(C),2023.04 - 2026.03

  • Grant-in-Aid for Scientific Research(C),2021.04 - 2023.03

  • Grant-in-Aid for Scientific Research(C),2020.04 - 2023.03

  • Grant-in-Aid for Research Activity start-up,2018.04 - 2019.03