Updated on 2023/11/30

写真a

 
NAKANO Tomoyuki
 
Date of Birth
1974
Contact information
メールアドレス
Laboratory Phone number
+80-23-628-5209
　
Laboratory Fax number
+81-23-628-5210
　

Research Areas

  • Life Science / Anatomy

Graduating School

  • Yamagata University, Faculty of Science

    2001.03, Graduated

Graduate School

  • Yamagata University, Graduate School, Division of Medical Sciences

    Doctor's Course, 2007.03, Completed

 

Papers

  • R59949, a diacylglycerol kinase inhibitor, inhibits inducible nitric oxide production through decreasing transplasmalemmal L-arginine uptake, Nauryn-Schmiedeberg’s Archives of Pharmacology, 390 207-214, 2017

    Shimomura T., Nakano T., Goto K. and Wakabayashi I

    Multiple Authorship (Only Japanese)

  • DaMab-2: Anti-Human DGK alpha Monoclonal Antibody for immunocytochemistry, Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 36 181-184, 2017

    Nakano T., Ogasawara S., Tanaka T., Hozumi Y., Mizuno S., Satoh E., Sakane F., Okada M., Taketomi A., Honma R., Nakamura T., Saidoh N., Yanaka M., Itai S., Handa S., Chang Yao-Wen, Yamada S., Kaneko M...

    Multiple Authorship (Only Japanese)

  • Localization of diacylglycerol kinase zeta in rat pancreatic islet cells under normal and streptozotocin-induced stress condition, Archives of Histology and Cytology, 76 23-33, 2016

    Hozumi Y., Nakano T., Tanaka T. and Goto K

    Multiple Authorship (Only Japanese)

  • Downregulation of diacylglycerol kinase zeta enhances activation of cytokine-induced NF-kB signaling pathway, BBA - Molecular Cell Research, 1853 , 2015

    Tsuchiya R., Tanaka T., Hozumi Y., Nakano T., Okada M., Topham M.K., Iino M., and Goto K

    Multiple Authorship (Including Foreigners)

  • Orotate phosphoribosyl transferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil, Biomedical Research, 36 403-409, 2015

    Hozumi Y., Tanaka T., Nakano T., Matsui H., Nasu T., Koike S., Kakehata S., Ito T. and Goto K

    Multiple Authorship (Only Japanese)

  • Expression of mRNAs for the diacylglycerol kinase family in immune cells during an inflammatory reaction, Biomedical Research, 35 61-68, 2014

    Yamamoto M., Tanaka T., Hozumi Y., Saino-Saito S., Nakano T., TajimaK., Kato T. and Goto K

    Multiple Authorship (Only Japanese)

  • Role of the N-terminal hydrophobic residues of DGK epsilon in targeting the endoplasmic reticulum, BBA Molecular and Cell Biology of Lipids, 1842 1440-1450, 2014

    Matsui H., Hozumi Y., Tanaka T., Okada M., Nakano T., Suzuki Y., Iseki K., Kakehata S., Topham M.K. and Goto K.

    Multiple Authorship (Including Foreigners)

  • Diacylglycerol kinase eta modulates oncogenic properties of lung cancer cells harboring mutant epidermal growth factor, Clinical and Translational Oncology, 16 29-35, 2014

    Nakano T., Iravani A., Kim M., Hozumi Y., Lohse M., Reichert E.C., Crotty T.M., Stafforini D.M. and Topham M.K.

    Multiple Authorship (Including Foreigners)

  • Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc min/+ mice, Cancer Research, 73 2806-2816, 2013

    Xu C., Reichert E.C., Nakano T., Lohse M., Gardner A.G., Revelo M.P., Topham M.K. and Stafforini D.M.

    Single Author

  • Diacylglycerol kinase delta modulates Akt phosphorylation through pleckstrin homology domain leucin-rich repeat protein phophatase 2 (PHLPP2), Journal of Biological Chemistry, 288 1439-1447, 2013

    Crotty T.M., Nakano T., Stafforini D.M. and Topham M.K

    Multiple Authorship (Including Foreigners)

  • Involvement of diacylglycerol kinase gamma in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells., Naunyn-Schmiedeberg’s Archives of Pharmacology, 385 787-795, 2012.05

    T. Nakano, Y. Hozumi, K. Goto and I. Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Altered expression of diacylglycerol kinase isozymes in regenerating liver., Journal of Histochemistry and Cytochemistry, 60 130-138, 2012.04

    T. Nakano, Y. Hozumi, K. Okumoto, K Iseki, T. Saito, S. Kawata, I. Wakabayashi and K. Goto

    Multiple Authorship (Including Foreigners)

  • Inhibition of thrombin-induced Ca2+ influx in platelet by R59949, an inhibitor of diacylglycerol kinase, Journal of Pharmacy and Pharmacology, 64 855-861, 2012.03

    M. Marumo, T. Nakano, Y Takeda, K. Goto and I Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Nuclear relocation of DGK zeta in cardiomyocytes under the conditions of ischemia/reperfusion, Histology and Histopathology, 11 1383-1390, 2011.06

    H. Akiyama, Y. Hozumi. T. Nakano, I. Kubota and K. Goto

    Multiple Authorship (Including Foreigners)

  • Docetaxel inhibit cyclooxygenase-2 induction in vascular smooth muscle cells, European Journal of Pharmacology, 654 150-154, 2011.01

    T. Nakano, K. Goto and I. Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Identification of Cells Expressing COX-2 in Response to Interleukin-1beta　in Rat Aortae, Journal of Pharmacological Science, 113 84-88, 2010.10

    T. Nakano and I. Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Enhancement of interleukin-1beta-induced iNOS expression in cultured vascular smooth muscle cells of Goto-Kakizaki diabetes rats, European Journal of Pharmacology, 629 1-6, 2010.04

    I. Wakabayashi, T. Nakano and Y. Takahashi

    Multiple Authorship (Including Foreigners)

  • Brain trauma induces expression of diacylglycerol kinase zeta in microglia., Neuroscience letters, 461 110-115, 2009.08

    T. Nakano, K. Iseki, Y. Hozumi, K. Kawamae, I. Wakabayashi and K. Goto

    Multiple Authorship (Including Foreigners)

  • Localization of diacylglycerol kinase epsilon on stress fibers in vascular smooth muscle cells., Cells and Tissue Research, 337 167-175, 2009.04

    T. Nakano, Y. Hozumi, K. Goto, and I. Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Diacylglycerol kinase zeta is associated with chromatin, but dissociates from condensed chromatin during mitotic phase in NIH3T3 cells., Journal of Cellular Biochemistry, 105 756-765, 2008.10

    H. Hasegawa, T. Nakano, Y. Hozumi, M. Takagi, T. Ogino, M. Okada, H. Kondo, M. Watanabe, A. M. Martelli and K. Goto

    Multiple Authorship (Including Foreigners)

  • Increased induction of inducible nitric oxide synthase expression in aortae of type 2 diabetes rats., Journal of Pharmacological Science, 107 190-200, 2008.10

    Y. Takahashi, T. Nakano and I Wakabayashi

    Multiple Authorship (Including Foreigners)

  • Diacylglycerol kinase zeta is involved in the process of cerebral infarction., European Journal of Neuroscience, 23 1427-1435, 2006.04

    T. Nakano, Y. Hozumi, H. Ali, S. Saino-Saito, H. Kamii, S. Sato, T. Kayama, M. Watanabe, H. Kondo and K. Goto

    Multiple Authorship (Including Foreigners)

  • Diacylglycerol kinase and animal models: The pathophysiological roles in the brain and heart, Advances in Enzyme Regulation, 46 192-202, 2006.04

    K. Goto K., T. Nakano and Y. Hozumi

    Multiple Authorship (Including Foreigners)

  • Nuclear localization of diacylglycerol kinase zeta in neurons, European Journal of Neuroscience, 18 1448-1458, 2006.04

    Y. Hozumi, T. Ito, T. Nakano, T. Nakagawa, M. Aoyagi, H. Kondo and K. Goto

    Multiple Authorship (Including Foreigners)

  • Selective translocation of diacylglycerol kinase zeta in hippocampal neurons under transient forebrain ischemia, Neuroscience letters, 372 190-195, 2004.04

    H. Ali H, T. Nakano, S. Saino-Saito, Y. Hozumi, Y. Katagiri, H. Kamii, S. Sato, T. Kayama, H. Kondo and K. Goto

    Multiple Authorship (Including Foreigners)

  • Tegumentary papillae of Echinostoma caproni cercariae (Trematoda: Echinostomatidae)., Parasitology Research, 89 446-450, 2003.04

    T. Nakano, T. Fujino, H. Washioka, A. Tonosaki, K. Goto and B. Fried

    Multiple Authorship (Including Foreigners)

  • Comparative ultrastructure of eggs in Echinostoma paraensei, E. caproni, and E. trivolvis (Trematoda: Echinostomatidae), Parasitology Research, 86 427-430, 2003.04

    T. Fujino, T. Nakano, H. Washioka, A. Tonosaki, H. Ichikawa, B. Fried

    Multiple Authorship (Including Foreigners)

  • The expulsion of Echinostoma trivolvis: worm kinetics and intestinal cytopathology in Jirds, Meriones unguiculatus. , Comparative Parasitology, 69 236-240, 2000.04

    T. Fujino, T. Shinohara, K. Fukuda, H. Ichikawa, T. Nakano and B. Fried

    Multiple Authorship (Including Foreigners)

display all >>

Books

  • Methods for measuring the activity of diacylglycerol kinase, in Lipid mediated signaling., CRC press, 2010.01

    K. Goto, Y. Hozumi, T. Nakano, A. M. Martelli and H. Kondo

Review Papers

  • Reciprocal regulation of p53 and NF-kappaB by diacylglycerol kinase zeta, Advances in Biological Regulation, 15 30012-30019, 2015

    Tanaka T., Tsuchiya R., Hozumi Y., Nakano T., Okada M. and Goto K

  • Roles of lipid modulating enzymes DGK and COX in phathophysiological condition, Anatomical Science International, 90 22-32, 2015

    Nakano T

  • DGKζ under stress conditions: “to be nuclear or cytoplasmic, that is the question”, Advances in Biological Regulation, 54 242-253, 2013

    Goto K., Tanaka T., Nakano T., Okada M., Hozumi Y., Topham M.K. and Martelli A.M

  • Lipid messenger, diacylglycerol, and its regulator diacylglycerol kinase in cells, organs, animals: history and perspective, Tohoku Journal of Experimental Medicine, 214 199-212, 2008

    Goto K., Hozumi Y., Nakano T., Saino-Saito S. and Martelli A.M

  • Cellular biology and pathophysiology of diacylglycerol kinase family, an enzyme responsible for lipid second messenger metabolism: morphological aspects in tissues and organs, International Review of Cytology, 264 25-63, 2007

    Goto K., Hozumi Y., Nakano T., Saino-Saito S., and Kondo H

  • Diacylglycerol kinase and animal models: The pathophysiological roles in the brain and heart., Advances in Biological Regulation, 46 192-202, 2006

    Goto K., Nakano T. and Hozumi Y

display all >>

Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Scientific Research(C)，2023.04 - 2026.03

  • Grant-in-Aid for Scientific Research(B)，2021.04 - 2022.03

  • Grant-in-Aid for Scientific Research(C)，2020.04 - 2023.03

  • Grant-in-Aid for Scientific Research(B)，2018.04 - 2020.03

  • Grant-in-Aid for Scientific Research(C)，2017.04 - 2020.03

  • Grant-in-Aid for Young Scientists(B)，2008.04 - 2010.03

display all >>