Measurement of mechanical dynamics in biomolecular interactions, 2011.04 - 2013.03

RNA chaperone, RNA conformational change, QCM, energy dissipation

Dynamic viscoelasticity measurements of a DNA-gel film for preparation of perfect elastic gel, 2013.04 - 2016.03

Noninvasive Sweat-Lactate Biosensor Emplsoying a Hydrogel-Based Touch Pad, SCIENTIFIC REPORTS, 9(1) 10102, 2019.07

Nagamine Kuniaki, Mano Taisei, Nomura Ayako, Ichimura Yusuke, Izawa Ryota, Furusawa Hiroyuki, Matsui Hiroyuki, Kumaki Daisuke, Tokito Shizuo

Multiple Authorship (Only Japanese)

Formaldehyde Detection by a Combination of Formaldehyde Dehydrogenase and Chitosan on a Sensor Based on an Organic Field-Effect Transistor, TECHNOLOGIES, 7(3) , 2019.07

Tsuchiya Kazuhiko, Furusawa Hiroyuki, Nomura Ayako, Matsui Hiroyuki, Nihei Mizuhisa, Tokito Shizuo

Multiple Authorship (Only Japanese)

Entropy-Driven Mechanisms between Disulfide-Bond Formation Protein A (DsbA) and B (DsbB) in Escherichia coli, ACS OMEGA, 4(5) 8341-8349, 2019.05

Yazawa Kenjiro, Furusawa Hiroyuki

Multiple Authorship (Only Japanese)

An L-lactate Biosensor based on Printed Organic Inverter Circuitry and with a Tunable Detection Limit, Sensors and Materials, 31(4) 1205-1213, 2019.04

Kuniaki Nagamine, Taisuke Mano, Rei Shiwaku, Hiroyuki Furusawa, Hiroyuki Matsui, Daisuke Kumaki, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Synthesis, Assembled Structures, and DNA Complexation of Thermoresponsive Lysine-Based Zwitterionic and Cationic Block Copolymers, LANGMUIR, 35(13) 4646-4659, 2019.04

Kanto Ryosuke, Qiao Yehan, Masuko Kazunori, Furusawa Hiroyuki, Yano Shigekazu, Nakabayashi Kazuhiro, Mori Hideharu

Multiple Authorship (Including Foreigners)

Printed Organic Transistor-Based Enzyme Sensor for Continuous Glucose Monitoring in Wearable Healthcare Applications, ChemElectroChem, 5 3881-3886, 2018.10

Taisei Mano, Kuniaki Nagamine, Yusuke Ichimura, Rei Shiwaku, Hiroyuki Furusawa, Hiroyuki Matsui, Daisuke Kumaki, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Charge-Accumulative Potentiometric Measurements for Ammonia Detection Using an Enzymatic Cascade Reaction on a Prussian Blue Electrode, Chem. Lett., 47 1412-1415, 2018.09

Kai Sasaki, Hiroyuki Furusawa, Kuniaki Nagamine, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Detection of 1,5-anhydroglucitol as a Biomarker for Diabetes Using an Organic Field-Effect Transistor-Based Biosensor, Technologies, 6 77, 2018.08

Hiroyuki Furusawa, Yusuke Ichimura, Kuniaki Nagamine, Rei Shiwaku, Hiroyuki Matsui, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Detection of odorant molecules in gaseous phase using α-, β-, and γ-cyclodextrin films on a quartz crystal microbalance, Technologies, 6 63, 2018.07

Kai Sasaki, Hiroyuki Furusawa, Kuniaki Nagamine, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Electric charge detection of sparse organic acid molecules using an Organic Field-Effect Transistor (OFET)-based sensor, Bull. Chem. Soc. Jpn., 91 1020-1025, 2018.06

Hiroyuki Furusawa, Yusuke Ichimura, Shuhei Harada, Mayu Uematsu, Shenyao Xue, Kuniaki Nagamine, and Shizuo Tokito

Multiple Authorship (Including Foreigners)

Probing multiple binding modes of DNA hybridization: A comparison between single-molecule observations and ensemble measurements, ACS Omega, 3 2084-2092, 2018.02

Kenjjiro Yazawa and Hiroyuki Furusawa

Multiple Authorship (Including Foreigners)

Hydration and viscoelastic properties of high- and low-density polymer brushes using a Quartz-Crystal Microbalance based on admittance analysis (QCM-A), Macromolecules, 49 3463-3470, 2016.04

Hiroyuki Furusawa, Tomomi Sekine, Tomomitsu Ozeki

Multiple Authorship (Including Foreigners)

Kinetic characterization of small DNA-binding molecules interacting with a DNA-strand on a quartz crystal microbalance, Anal. Biochem., 492 34-42, 2016.01

Hiroyuki Furusawa, Hajime Nakayama, Mariko Funasaki, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

DNA compaction determined by energy dissipation measurements on a quartz-crystal oscillator, Microsyst. Technol., 22(1) 65-71, 2015.08

Hiroyuki Furusawa and Tomomitsu Ozeki

Multiple Authorship (Including Foreigners)

In Situ Monitoring of Structural Changes during Formation of 30S Translation Initiation Complex by Energy Dissipation Measurement Using 27-MHz Quartz-Crystal Microbalance, Analytical Chemistry, 86 5406-5415, 2014.05

Hiroyuki Furusawa, Yumi Tsuyuki, Shuntaro Takahashi, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Arginine Arrangement of Bacteriophage λ N-Peptide Plays a Role as a Core Motif of GNRA Tetraloop-RNA Binding Peptides, ChemBioChem, 15 865-871, 2014.03

Hiroyuki Furusawa, Shinobu Fukusho, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Real-time Monitoring of Intermediates Reveals the Reaction Pathway in the Thiol-Disulfide Exchange between Disulfide Bond Formation Protein A (DsbA) and B (DsbB) on a Membrane-immobilized Quartz Crystal Microbalance (QCM) System, The Journal of Biological Chemistry, 288(50) 35969-35981, 2013.12

Kenjiro Yazawa, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Translation Enhancer Improves the Ribosome Liberation from Translation Initiation, J. Am. Chem. Soc., 135 13096-13106, 2013.08

Shuntaro Takahashi, Hiroyuki Furusawa, Takuya Ueda, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Mechanism of ThiolDisulfide Exchange Reactions between DsbA and DsbB over a Wide pH Range, Chemistry Letters, 42 241-243, 2013.03

Kenjiro Yazawa, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

In situ monitoring of a trace intermediate during DNA phosphorylation by T4 polynucleotide kinase for transient kinetic studies, Analyst, 137 1334-1337, 2012.01

37） Hiroyuki Furusawa, Kensuke Uemura, Hiroshi Yoshimine, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Small mass-change detectable quartz crystal microbalance and its application to enzymatic one-base elongation on DNA, Analytical Chemistry, 83 8741-8747, 2011.10

36） Hiroshi Yoshimine, Taisuke Kojima, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Real-time monitoring of cell-free translation on a quartz-crystal microbalance, J. AM. CHEM. SOC., 131 9326-9332, 2009.04

35） Shuntaro Takahashi, Masaaki Iida, Hiroyuki Furusawa, Yoshihiro Shimizu, Takuya Ueda, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Added mass effect on immobilizations of proteins on a 27 MHz quartz crystal microbalance in aqueous solution , Analytical Chemistry, 81(6) 2268-2273, 2009.03

34） Hiroyuki Furusawa, Tomomitsu Ozeki, Mizuki Morita, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

In situ monitoring of conformational changes of and peptide bindings to calmodulin on a 27 MHz quartz-crystal microbalance, Analytical Chemistry, 81(5) 1841-1847, 2009.01

Hiroyuki Furusawa, Mayu Komatsu, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Direct monitoring of allosteric recognition of type IIE restrictionendonuclease EcoRII, Journal of Biological Chemistry, 283(22) 15023-15030, 2008.05

Shuntaro Takahashi, Hisao Matsuno, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

70S Ribosomes bind to Shine-Dalgarno sequences without required dissociations, ChemBioChem, 9 870-873, 2008.03

Shuntaro Takahashi, Ryoko Akita, Hisao Matsuno, Hiroyuki Furusawa, Yoshihiro Shimizu

Multiple Authorship (Including Foreigners)

Transient kinetic studies of pH-dependent hydrolyses by exo-type Carboxypeptidase P on a 27-MHz quartz crystal microbalance , Analytical Chemistry, 80(4) 1005-1011, 2008.02

Hiroyuki Furusawa, Hiroki Takano, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Transient kinetic studies of protein hydrolyses by endo- and exo-proteases on a 27 MHz quartz-crystal microbalance , Organic & Biomolecular Chemistry, 6 727-731, 2008.01

Hiroyuki Furusawa, Hiroki Takano, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

IgG Binding Kinetics to oligo B Protein A Domains on Lipid Layers Immobilized on a 27 MHz Quartz Crystal Microbalance, JOURNAL OF MOLECULAR RECOGNITION, 20 83-89, 2007.01

Hideyuki Mitomo, Hideki Shigematsu, Eiry Kobatake, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Monitoring of EcoRV Digestions on a DNA-immobilized Quartz Crystal Microbalance, Chemistry Letters, 36(2) 230-231, 2006.12

Shuntaro Takahashi, Hisao Matsuno, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Kinetic Analyses of Divalent Cation-dependent EcoRV Digestions on a DNA-immobilized Quartz Crystal Microbalance, Analytical Biochemistry, 361 210-217, 2006.12

Shuntaro Takahashi, Hisao Matsuno, Hiroyuki Furusawa, Yoshio Okahata

Multiple Authorship (Including Foreigners)

Hydration and Energy Dissipation Measurements of Biomolecules on a Piezoelectric Quartz Oscillator by Admittance Analyses , Analytical Chemistry, 79(1) 79-88, 2006.01

Tomomitsu Ozeki, Mizuki Morita, Hiroshi Yoshimine, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Evaluation of RNA Structures by using a Probe-immobilized 27 MHz Quartz Crystal Microbalance, Chemistry Letters, 35(1) 46-47, 2006.01

Tomomitsu Ozeki, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Kinetic Studies of DNA Cleavage Reactions catalyzed by an ATP-dependent Deoxyribonuclease on a 27-MHz Quartz-Crystal Microbalance, Biochemistry, 44 2262-2270, 2005.01

Hisao Matsuno, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Optimization of Nuclear Localization signal for nuclear transport of DNA-encapsulating Particles, Journal of Controlled Release, Journal of Controlled Release, 104 507-519, 2005.01

Akiko Eguchi, Hiroyuki Furusawa, Akitsugu Yamamoto, Teruo Akuta, Mamoru Hasegawa, Yoshio Okahata, and Mahito Nakanishi

Multiple Authorship (Including Foreigners)

Kinetic Study of Phosphorylation-dependent Complex Formation between the Kinase-Inducible Domain (KID) of CREB and the KIX Domain of CBP on a Quartz Crystal Microbalance, Chem. Eur. J, 10 6172-6178, 2004.10

Hisao Matsuno, Hiroyuki Furusawa, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

In Vitro Selection of N-Peptide-Binding RNA on a Quartz-Crystal Microbalance to Study a Sequence-Specific Interaction between the Peptide and Loop RNA , ChemBioChem, (2-3) 217-220, 2003.02

Hiroyuki Furusawa, Akiko Murakawa, Shinobu Fukusho, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Direct Monitoring of DNA Cleavages Catalyzed by an ATP-dependent Deoxyribonuclease on a 27 MHz Quartz-Crystal Microbalance, Chemical Communications, 470-471, 2002.02

Hisao Matsuno, Hiroyuki Furusawa and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Binding Kinetics of the Toroid-Shaped PCNA to DNA Strands on a 27 MHz Quartz Crystal Microbalance, ChemPhysChem, (5) 446-448, 2002.01

Hiroyuki Furusawa, Yoji Kitamura, Naoto Hagiwara, Toshiki Tsurimoto, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

In Vitro Selection and Evaluation of RNA Aptamers that Recognize Arginine-rich-motif Model Peptide on a Quartz-Crystal Microbalance , Chemical Communications, 88-89, 2001.12

Shinobu Fukusho, Hiroyuki Furusawa and Yoshio Okahata

Multiple Authorship (Including Foreigners)

A Highly Sensitive 27 MHz Quartz-Crystal Microbalance as a Device for Kinetic Measurements of Molecular Recognition on a DNA Strands , Analytical Sciences, 16 1113-1119, 2000.11

Yoshio Okahata, Kenichi Niikura, Hiroyuki Furusawa, and Hisao Matsuno

Multiple Authorship (Including Foreigners)

In situ Monitoring of Poly(L-glutamine)-Bound dsDNA Selection on a Quartz-Crystal Microbalance , Chemistry Letters, 823-824, 1999.09

Hiroyuki Furusawa, Yasuhito Ebara, and Yoshio Okahata

Multiple Authorship (Including Foreigners)

Kinetic Measurements of DNA Hybridization on an Oligonucleotide-Immobilized 27-MHz Quartz Crystal Microbalance , Analytical Chemistry, 70(7) 1288-1296, 1998.02

Yoshio Okahata, Masanori Kawase, Kenichi Niikura, Fuyuka Ohtake, Hiroyuki Furusawa, and Yasuhito Ebara

Multiple Authorship (Including Foreigners)

Grant-in-Aid for Young Scientists(B)，2005.04 - 2007.03

Grant-in-Aid for Young Scientists(B)，2003.04 - 2005.03

Grant-in-Aid for JSPS Fellows，1998.04 - 2000.03