Updated on 2026/02/20

写真a

 
SEINO Manabu
 
Title
Lecturer

Degree

  • Doctor (Medicine), Yamagata University, 2016.09

 

Papers

  • Investigation of tumor mutation burden using the comprehensive genomic profiling data of vulvar and vaginal malignant tumors: an observational study using C-CAT database, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 30(5) 1033-1039, 2025.05

    Seino, M; Sano, S; Gonai, Y; Horikawa, S; Nakamura, F; Okui, Y; Matsukawa, J; Sakaki, H; Watanabe, N; Yamauchi, K; Ohta, T; Hoshi, Y; Suzuki, S; Kawai, M; Nagase, S

    Single Author

  • Quality indicators for endometrial cancer care in Japan., Journal of gynecologic oncology, 2025.03

    Kakuwa T, Ichinose Y, Rikitake R, Ishii T, Nagase S, Kobayashi Y, Kaneuchi M, Tokunaga H, Seino M, Kajiyama H, Takekuma M, Tabata T, Terai Y, Terao Y, Morisada T, Watari H, Yamamoto Y, Kawata A, Higas...

    Single Author

  • Revision of quality indicators for cervical cancer and trend analysis of existing indicators in Japan., Journal of gynecologic oncology, 2025.03

    Kakuwa T, Rikitake R, Nagase S, Mikami M, Baba T, Kaneuchi M, Tokunaga H, Seino M, Muramatsu T, Yamagami W, Takehara K, Niikura H, Hirashima Y, Yoshino K, Ichinose Y, Kawata A, Higashi T

    Single Author

  • Clinical Characteristics and Chemosensitivity in Germline TP53 Pathogenic Variant Cases Identified by Cancer Genomic Testing, CANCER GENOMICS & PROTEOMICS, 22(2) 354-362, 2025.03

    Saito, Y; Hoshi, Y; Sato, M; Seino, M; Watanabe, N; Kawai, M; Suzuki, S

    Single Author

  • Comparison of Treatment Outcomes Between First-Line Chemotherapy With or Without Bevacizumab for Advanced Ovarian Clear Cell Carcinoma (Tohoku Gynecologic Cancer Unit: TGCU-RS001A Study), CANCERS, 16(22) 3801, 2024.11

    Shoji, T; Takatori, E; Nagasawa, T; Kagabu, M; Baba, T; Shigeto, T; Matsumura, Y; Shimizu, D; Terada, Y; Seino, M; Ohta, T; Nagase, S; Shigeta, S; Tokunaga, H; Shimada, M; Kaiho-Sakuma, M; Furukawa, S...

    Single Author

  • Profiling of metabolic dysregulation in ovarian cancer tissues and biofluids, SCIENTIFIC REPORTS, 14(1) 21555, 2024.09

    Ohta, T; Sugimoto, M; Ito, Y; Horikawa, S; Okui, Y; Sakaki, H; Seino, M; Sunamura, M; Nagase, S

    Single Author

  • Japan Society of Gynecologic Oncology 2022 guidelines for uterine cervical neoplasm treatment, JOURNAL OF GYNECOLOGIC ONCOLOGY, 35(1) e15, 2024.01

    Seino, M; Nagase, S; Tokunaga, H; Yamagami, W; Kobayashi, Y; Tabata, T; Kaneuchi, M; Hirashima, Y; Niikura, H; Yoshino, K; Takehara, K; Baba, T; Katabuchi, H; Mikami, M

    Single Author

  • がんゲノム検査に携わる医療スタッフへのコミュニケーションスキルトレーニング, 日本癌治療学会学術集会抄録集, 61回 PR-4, 2023.10

    鈴木 修平, 鏡 優子, 鈴木 理恵, 齋藤 陽介, 佐藤 正道, 清野 学, 永瀬 智

    Single Author

  • Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(14) , 2023.07

    Idei, U; Ohta, T; Yamatani, H; Seino, M; Nagase, S

    Single Author

  • Impact of adjuvant chemotherapy on the overall survival of patients with resectable bulky small cell neuroendocrine cervical cancer: a JSGO-JSOG joint study, JOURNAL OF GYNECOLOGIC ONCOLOGY, 34(1) e4, 2023.01

    Seino, M; Nagase, S; Ohta, T; Yamagami, W; Ebina, Y; Kobayashi, Y; Tabata, T; Kaneuchi, M; Enomoto, T; Mikami, M

    Single Author

  • Activation of estrogen receptor α by estradiol and cisplatin induces platinum-resistance in ovarian cancer cells., Cancer biology & therapy, 18(9) 730-739, 2017.09

    Matsumura S, Ohta T, Yamanouchi K, Liu Z, Sudo T, Kojimahara T, Seino M, Narumi M, Tsutsumi S, Takahashi T, Takahashi K, Kurachi H, Nagase S

    Multiple Authorship (Only Japanese)

  • Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel, Oncology Report, 2016.01

    Manabu Seino, Masashi Okada, Hirotsugu Sakaki, Hiroaki Takeda, Hikaru Watarai, Shuhei Suzuki, Sizuka Seino, Kenta Kuramoto, Tsuyoshi Ohta, Satoru Nagase, Hirohisa Kurachi, Chifumi Kitanaka

    Multiple Authorship (Only Japanese)

  • GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells., Anticancer research, 35(12) 6607-6614, 2015.12

    Sakaki H, Okada M, Kuramoto K, Takeda H, Watarai H, Suzuki S, Seino S, Seino M, Ohta T, Nagase S, Kurachi H, Kitanaka C

    Multiple Authorship (Only Japanese)

  • JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells., Oncotarget, 6(1) 458-470, 2015.01

    Suzuki S, Okada M, Shibuya K, Seino M, Sato A, Takeda H, Seino S, Yoshioka T, Kitanaka C

    Multiple Authorship (Only Japanese)

  • Differential contribution of ROS to resveratrol-induced cell death and loss of self-renewal capacity of ovarian cancer stem cells., Anticancer research, 35(1) 85-96, 2015.01

    Seino M, Okada M, Shibuya K, Seino S, Suzuki S, Takeda H, Ohta T, Kurachi H, Kitanaka C

    Multiple Authorship (Only Japanese)

  • Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells., Oncotarget, 6(2) 651-661, 2015.01

    Shibuya K, Okada M, Suzuki S, Seino M, Seino S, Takeda H, Kitanaka C

    Multiple Authorship (Only Japanese)

  • Requirement of JNK signaling for self-renewal and tumor-initiating capacity of ovarian cancer stem cells., Anticancer Research, 34(9) 4723-4731, 2014.09

    Manabu Seino, Masashi Okada, Keita Shibuya, Sizuka Seino, Shuhei Suzuki, Tsuyoshi Ohta, Hirohisa Kurachi, Chifumi Kitanaka

    Multiple Authorship (Only Japanese)

  • Targeting the K-Ras--JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation., Oncotarget, 5(13) 5100-5112, 2014.07

    Okada M, Shibuya K, Sato A, Seino S, Suzuki S, Seino M, Kitanaka C

    Multiple Authorship (Only Japanese)

  • High levels of Wilms' tumor 1 (WT1) expression were associated with aggressive clinical features in ovarian cancer., Anticancer research, 34(5) 2331-2340, 2014.05

    Liu Z, Yamanouchi K, Ohtao T, Matsumura S, Seino M, Shridhar V, Takahashi T, Takahashi K, Kurachi H

    Multiple Authorship (Only Japanese)

  • JNK contributes to temozolomide resistance of stem-like glioblastoma cells via regulation of MGMT expression., International journal of oncology, 44(2) 591-599, 2014.02

    Okada M, Sato A, Shibuya K, Watanabe E, Seino S, Suzuki S, Seino M, Narita Y, Shibui S, Kayama T, Kitanaka C

    Multiple Authorship (Only Japanese)

  • Specific role of JNK in the maintenance of the tumor-initiating capacity of A549 human non-small cell lung cancer cells., Oncology reports, 30(4) 1957-1964, 2013.10

    Okada M, Shibuya K, Sato A, Seino S, Watanabe E, Suzuki S, Seino M, Kitanaka C

    Multiple Authorship (Only Japanese)

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Grant-in-Aid for Scientific Research

  • Grant-in-Aid for Scientific Research(C),2025.04 - 2026.03

  • Grant-in-Aid for Scientific Research(C),2024.04 - 2026.03

  • Grant-in-Aid for Scientific Research(C),2021.04 - 2023.03

  • Grant-in-Aid for Scientific Research(C),2021.04 - 2023.03

  • Grant-in-Aid for Scientific Research(C),2018.04 - 2021.03

  • Grant-in-Aid for Scientific Research(C),2018.04 - 2020.03

  • Grant-in-Aid for Scientific Research(C),2018.04 - 2019.03

  • Grant-in-Aid for Young Scientists(B),2017.04 - 2019.03

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