Updated on 2021/06/18

写真a

 
OHTA Yasuyuki
 

Research Areas

  • Life Science / General internal medicine

Graduating School

  • Okayama University, Faculty of Medicine

    2000.03, Graduated

Graduate School

  • Okayama University

    Doctor's Course, 2007.03, Completed

External Career

  • Okayama University, Lecturer, 2015.04 - 2020.03

  • , Professor, 2020.04 -

 

Papers

  • 新規モデルマウスにおいて低灌流はミトコンドリアの変化を伴う血管リモデリングを加速させる(Hypoperfusion accelerates vascular remodeling with mitochondrial changes in a novel mouse model), 脳循環代謝, 31(1) 130, 2019.11

    馮 田, 山下 徹, 太田 康之, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • 脳低灌流状態はミトコンドリアのダイナミクスを変化させAD病態を加速する(Hypoperfusion accelerates AD pathology with the change of mitochondrial dynamics), Dementia Japan, 33(4) 514, 2019.10

    馮 田, 山下 徹, 太田 康之, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • アルツハイマー病の進行に関する臨床的予測因子(Clinical predictors of Alzheimer's disease progression), Dementia Japan, 33(4) 523, 2019.10

    菱川 望, 表 芳夫, 武本 麻美, 太田 康之, 山下 徹, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • アルツハイマー病(脳低灌流)モデルマウスにおけるNLRP3インフラマソームの形成促進(Acceleration of NLRP3 inflammasome in Alzheimer's disease hypoperfusion model mouse), 脳循環代謝, 30(1) 138, 2018.10

    商 敬偉, 山下 徹, 太田 康之, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • Detecting spinal pyramidal tract of amyotrophic lateral sclerosis patients with diffusion tensor tractography, Neuroscience Research, 133 58-63, 2018.08

    Yusuke Fukui, Nozomi Hishikawa, Kota Sato, Yumiko Nakano, Ryuta Morihara, Jingwei Shang, Mami Takemoto, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • A migration case of Kii amyotrophic lateral sclerosis/parkinsonism dementia complex with the shortest stay in the endemic area and the longest incubation to develop the disease, Journal of Clinical Neuroscience, 46 64-67, 2017.12

    Keiichiro Tsunoda, Toru Yamashita, Hitoshi Shimada, Emi Nomura, Yoshiaki Takahashi, Jingwei Shang, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Makoto Higuchi, Tetsuya Suhara, Yasumasa K...

    Multiple Authorship (Including Foreigners)

  • Serious hyponatremia induced by a combination of angiotensin II receptor blocker and thiazide caused deterioration of cognitive functions and psychological symptoms in an elderly Alzheimer's disease patient, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(6) 192-194, 2017.11

    Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • 虚血性ラット脳における血栓溶解後のNVU解離に及ぼすrivaroxaban前処理の効果(Pretreatment Effects with Rivaroxaban on NVU Dissociation after Thrombolysis in Ischemic Rat Brain), 脳循環代謝, 29(1) 218, 2017.11

    商 敬偉, 山下 徹, 中野 由美子, 太田 康之, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • Different clinical effect of four antidementia drugs for Alzheimer's disease patients depending on white matter severity, Geriatrics and Gerontology International, 17(11) 1991-1999, 2017.11

    Yusuke Fukui, Nozomi Hishikawa, Jin Ichinose, Kota Sato, Yumiko Nakano, Ryuta Morihara, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Therapeutic effects of drug switching between acetylcholinesterase inhibitors in patients with Alzheimer's disease, Geriatrics and Gerontology International, 17(11) 1843-1848, 2017.11

    Yasuyuki Ohta, Mohamed Darwish, Nozomi Hishikawa, Toru Yamashita, Kota Sato, Mami Takemoto, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Type 2 Alexander disease with a novel glial fibrillary acidic protein gene mutation and its unique clinical features, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(6) 183-185, 2017.11

    Yuko Kawahara, Toru Yamashita, Yasuyuki Ohta, Kota Sato, Emi Nomura, Mami Takemoto, Nozomi Hishikawa, Jingwei Shang, Tomokatsu Yoshida, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Therapeutic effects of drug switching between acetylcholinesterase inhibitors in patients with Alzheimer's disease., Geriatrics & gerontology international, 17(11) 1843-1848, 2017.11

    Yasuyuki Ohta, Mohamed Darwish, Nozomi Hishikawa, Toru Yamashita, Kota Sato, Mami Takemoto, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Japanese sibling cases of multiple sclerosis presenting with different clinical phenotypes, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(6) 186-188, 2017.11

    Kota Sato, Yasuyuki Ohta, Toru Yamashita, Keiichiro Tsunoda, Kentaro Deguchi, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Behavioral and affective features of amyotrophic lateral sclerosis patients, Journal of the Neurological Sciences, 381 119-125, 2017.10

    Yasuyuki Ohta, Kota Sato, Mami Takemoto, Yoshiaki Takahashi, Ryuta Morihara, Yumiko Nakano, Keiichiro Tsunoda, Emi Nomura, Nozomi Hishikawa, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Comprehensive effects of galantamine and cilostazol combination therapy on patients with Alzheimer's disease with asymptomatic lacunar infarction, Geriatrics and Gerontology International, 17(10) 1384-1391, 2017.10

    Nozomi Hishikawa, Yusuke Fukui, Kota Sato, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Time-dependent change of in vivo optical imaging of oxidative stress in a mouse stroke model, Journal of Neuroscience Research, 95(10) 2030-2039, 2017.10

    Yumiko Nakano, Toru Yamashita, Qian Li, Kota Sato, Yasuyuki Ohta, Ryuta Morihara, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Time dependent Change of In Vivo Optical Imaging of Oxidative Stress in a Mouse Stroke Model, JOURNAL OF NEUROSCIENCE RESEARCH, 95(10) 2030-2039, 2017.10

    Yumiko Nakano, Toru Yamashita, Qian Li, Kota Sato, Yasuyuki Ohta, Ryuta Morihara, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Antisense Oligonucleotides Reduce RNA Foci in Spinocerebellar Ataxia 36 Patient iPSCs, Molecular Therapy - Nucleic Acids, 8 211-219, 2017.09

    Kosuke Matsuzono, Keiko Imamura, Nagahisa Murakami, Kayoko Tsukita, Takuya Yamamoto, Yuishin Izumi, Ryuji Kaji, Yasuyuki Ohta, Toru Yamashita, Koji Abe, Haruhisa Inoue

    Multiple Authorship (Including Foreigners)

  • Occult chronic progressive cervical and thoracic myelopathy without evident magnetic resonance imaging lesion, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(5) 155-158, 2017.09

    Emi Nomura, Toru Yamashita, Yoshiaki Takahashi, Keiichiro Tsunoda, Jingwei Shang, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Hiroki Ueno, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR-1 and PAR-2., Journal of neuroscience research, 95(9) 1818-1828, 2017.09

    Ryuta Morihara, Toru Yamashita, Syoichiro Kono, Jingwei Shang, Yumiko Nakano, Kota Sato, Nozomi Hishikawa, Yasuyuki Ohta, Stefan Heitmeier, Elisabeth Perzborn, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Non-ketotic hyperosmolar coma after percutaneous endoscopic gastrostomy in an advanced stage of progressive supranuclear palsy, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(5) 162-164, 2017.09

    Koh Tadokoro, Kota Sato, Ryuta Morihara, Jingwei Shang, Mami Takemoto, Yasuyuki Ohta, Toru Yamashita, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Case of myasthenia gravis and Lambert-Eaton myasthenic syndrome overlap syndrome accompanied by autoimmune encephalitis and cerebellar ataxia with multiple neuronal antibodies, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(5) 152-154, 2017.09

    Yumiko Nakano, Emi Nomura, Toru Yamashita, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Dissociated recovery between dementia and parkinsonism by transvenous embolization of recurrent dural arteriovenous fistula, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(5) 159-161, 2017.09

    Yumiko Nakano, Emi Nomura, Masafumi Hiramatsu, Mami Takemoto, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Yasuyuki Ohta, Kenji Sugiu, Isao Date, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Dynamic Mislocalizations of Nuclear Pore Complex Proteins after Focal Cerebral Ischemia in Rat, JOURNAL OF NEUROSCIENCE RESEARCH, 95(9) 1745-1759, 2017.09

    Qian Li, Yasuyuki Ohta, Toru Yamashita, Jingwei Shang, Kentaro Deguchi, Tian Feng, Kota Sato, Nozomi Hishikawa, Yumiko Nakano, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Dynamic mislocalizations of nuclear pore complex proteins after focal cerebral ischemia in rat, Journal of Neuroscience Research, 95(9) 1745-1759, 2017.09

    Qian Li, Yasuyuki Ohta, Toru Yamashita, Jingwei Shang, Kentaro Deguchi, Tian Feng, Kota Sato, Nozomi Hishikawa, Yumiko Nakano, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR-1 and PAR-2, Journal of Neuroscience Research, 95(9) 1818-1828, 2017.09

    Ryuta Morihara, Toru Yamashita, Syoichiro Kono, Jingwei Shang, Yumiko Nakano, Kota Sato, Nozomi Hishikawa, Yasuyuki Ohta, Stefan Heitmeier, Elisabeth Perzborn, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Neuroprotective Effects of a Novel Antioxidant Mixture Twendee X in Mouse Stroke Model, Journal of Stroke and Cerebrovascular Diseases, 26(6) 1191-1196, 2017.06

    Momoko Kusaki, Yasuyuki Ohta, Haruhiko Inufusa, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Xia Liu, Jingwei Shang, Feng Tian, Yusuke Fukui, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Neuroprotective Effects of a Novel Antioxidant Mixture Twendee X in Mouse Stroke Model, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 26(6) 1191-1196, 2017.06

    Momoko Kusaki, Yasuyuki Ohta, Haruhiko Inufusa, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Xia Liu, Jingwei Shang, Feng Tian, Yusuke Fukui, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Different Characteristics of Anterior and Posterior Branch Atheromatous Diseases with or without Early Neurologic Deterioration, Journal of Stroke and Cerebrovascular Diseases, 26(6) 1314-1320, 2017.06

    Yoshiaki Takahashi, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Yasuhiro Manabe, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients, Neuroscience, 350 158-168, 2017.05

    Jingwei Shang, Toru Yamashita, Yumiko Nakano, Ryuta Morihara, Xianghong Li, Tian Feng, Xia Liu, Yong Huang, Yusuke Fukui, Nozomi Hishikawa, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Familial amyotrophic lateral sclerosis of the G37V-superoxide dismutase 1 mutation with a slow disease progression, NEUROLOGY AND CLINICAL NEUROSCIENCE, 5(3) 96-98, 2017.05

    Koh Tadokoro, Yasuyuki Ohta, Yoshiaki Takahashi, Toru Yamashita, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Factors related to continuous and discontinuous attendance at memory clinics, European Journal of Neurology, 24(5) 673-679, 2017.05

    N. Hishikawa, Y. Fukui, Y. Nakano, R. Morihara, M. Takemoto, K. Sato, T. Yamashita, Y. Ohta, K. Abe

    Multiple Authorship (Including Foreigners)

  • Ataxic form of autosomal recessive PEX10-related peroxisome biogenesis disorders with a novel compound heterozygous gene mutation and characteristic clinical phenotype, JOURNAL OF THE NEUROLOGICAL SCIENCES, 375 424-429, 2017.04

    Toru Yamashita, Jun Mitsui, Nobuyuki Shimozawa, Shigeo Takashima, Hiroshi Umemura, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Takashi Matsukawa, Hiroyuki Ishiura, Jun Yoshimura, Koichi...

    Multiple Authorship (Including Foreigners)

  • Cognitive and affective functions associated with insomnia: a population-based study, Neurological Research, 39(4) 331-336, 2017.04

    Nozomi Hishikawa, Yusuke Fukui, Kota Sato, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Flow-metabolism uncoupling in the cervical spinal cord of ALS patients, NEUROLOGICAL SCIENCES, 38(4) 659-665, 2017.04

    Toru Yamashita, Tetsuhiro Hatakeyama, Kota Sato, Yusuke Fukui, Nozomi Hishikawa, Yasuyuki Ohta, Yoshihiro Nishiyama, Nobuyuki Kawai, Takashi Tamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • アルツハイマー病患者におけるメタボリック症候群の影響, 日本認知症ケア学会誌, 16(1) 300, 2017.04

    福井 裕介, 菱川 望, 佐藤 恒太, 太田 康之, 山下 徹, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • Potential multisystem degeneration in Asidan patients, Journal of the Neurological Sciences, 373 216-222, 2017.02

    Yasuyuki Ohta, Toru Yamashita, Nozomi Hishikawa, Kota Sato, Kosuke Matsuzono, Keiichiro Tsunoda, Noriko Hatanaka, Mami Takemoto, Toshihiko Takemi, Kazuhiro Takamatsu, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) with Limbic Encephalitis, INTERNAL MEDICINE, 56(18) 2513-2518, 2017

    Yasuyuki Ohta, Emi Nomura, Keiichiro Tsunoda, Toru Yamashita, Yoshiaki Takahashi, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Novel Therapeutic Transplantation of Induced Neural Stem Cells for Stroke, CELL TRANSPLANTATION, 26(3) 461-467, 2017

    Toni Yamashita, Wentao Liu, Yoshiaki Matsumura, Ryosuke Miyagi, Yun Zhai, Momoko Kusaki, Nozomi Hishikawa, Yasuyuki Ohta, Sung Mm Kim, Tae Hwan Kwak, Dong Wook Han, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Successful delayed aortic surgery for a patient with ischemic stroke secondary to aortic dissection, Internal Medicine, 56(17) 2343-2346, 2017

    Ryuta Morihara, Toru Yamashita, Kentaro Deguchi, Keiichiro Tsunoda, Yasuhiro Manabe, Yoshiaki Takahashi, Taijun Yunoki, Kota Sato, Yumiko Nakano, Syoichiro Kono, Yasuyuki Ohta, Nozomi Hishikawa, Koji ...

    Multiple Authorship (Including Foreigners)

  • Novel therapeutic transplantation of induced neural stem cells for stroke, Cell Transplantation, 26(3) 461-467, 2017

    Toru Yamashita, Wentao Liu, Yoshiaki Matsumura, Ryosuke Miyagi, Yun Zhai, Momoko Kusaki, Nozomi Hishikawa, Yasuyuki Ohta, Sung Min Kim, Tae Hwan Kwak, Dong Wook Han, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Successful Delayed Aortic Surgery for a Patient with Ischemic Stroke Secondary to Aortic Dissection, INTERNAL MEDICINE, 56(17) 2343-2346, 2017

    Ryuta Morihara, Toru Yamashita, Kentaro Deguchi, Keiichiro Tsunoda, Yasuhiro Manabe, Yoshiaki Takahashi, Taijun Yunoki, Kota Sato, Yumiko Nakano, Syoichiro Kono, Yasuyuki Ohta, Nozomi Hishikawa, Koji ...

    Multiple Authorship (Including Foreigners)

  • Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with limbic encephalitis, Internal Medicine, 56(18) 2513-2518, 2017

    Yasuyuki Ohta, Emi Nomura, Keiichiro Tsunoda, Toru Yamashita, Yoshiaki Takahashi, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Emergency caesarean section saved both an anti-musk antibody-positive myasthenia gravis mother with pregnancy-induced hypertension and her premature baby, Internal Medicine, 56(24) 3361-3364, 2017

    Yoshiaki Takahashi, Toru Yamashita, Ryuta Morihara, Yumiko Nakano, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Yasuyuki Ohta, Kei Hayata, Hisashi Masuyama, Tomoka Okamura, Yosuke Washio, Koji Abe

    Multiple Authorship (Including Foreigners)

  • アルツハイマー病モデルマウスにおける慢性脳低灌流の強い影響(Strong Impact of Chronic Cerebral Hypoperfusion in Alzheimer's Disease Model Mouse), 脳循環代謝, 28(1) 235, 2016.11

    商 敬偉, 山下 徹, 太田 康之, 菱川 望, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • Differences between the behavioral and psychological symptoms of Alzheimer's disease and Parkinson's disease, Journal of the Neurological Sciences, 369 278-282, 2016.10

    Ryo Tokuchi, Nozomi Hishikawa, Kota Sato, Noriko Hatanaka, Yusuke Fukui, Mami Takemoto, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Temporal Profiles of Stress Protein Inductions after Focal Transient Ischemia in Mice Brain, Journal of Stroke and Cerebrovascular Diseases, 25(10) 2344-2351, 2016.10

    Qian Li, Yumiko Nakano, Jingwei Shang, Yasuyuki Ohta, Kota Sato, Mami Takemoto, Nozomi Hishikawa, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Effects of Pretreatment with Warfarin or Rivaroxaban on Neurovascular Unit Dissociation after Tissue Plasminogen Activator Thrombolysis in Ischemic Rat Brain, Journal of Stroke and Cerebrovascular Diseases, 25(8) 1997-2003, 2016.08

    Jingwei Shang, Toru Yamashita, Syoichiro Kono, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xianghong Li, Nozomi Hishikawa, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Peripheral arterial endothelial dysfunction of neurodegenerative diseases, Journal of the Neurological Sciences, 366 94-99, 2016.07

    Yusuke Fukui, Nozomi Hishikawa, Jingwei Shang, Kota Sato, Yumiko Nakano, Ryuta Morihara, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Comparative Gait Analysis in Progressive Supranuclear Palsy and Parkinson's Disease, European Neurology, 75(5-6) 282-289, 2016.07

    Noriko Hatanaka, Kota Sato, Nozomi Hishikawa, Mami Takemoto, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Age-dependent cognitive and affective differences in Alzheimer's and Parkinson's diseases in relation to MRI findings, Journal of the Neurological Sciences, 365 3-8, 2016.06

    Ryo Tokuchi, Nozomi Hishikawa, Kota Sato, Noriko Hatanaka, Yusuke Fukui, Mami Takemoto, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Prospective surveillance data of human prion disease in the Chugoku and Shikoku regions of Japan, PRION, 10 S90-S91, 2016

    Kota Sato, Nozomi Hishikawa, Yasuyuki Ohta, Toru Yamashita, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical features of incidental mild cognitive impairment and dementia in a population-based study, Geriatrics and Gerontology International, 2016

    Nozomi Hishikawa, Yusuke Fukui, Kota Sato, Toru Yamashita, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical Benefits of Rivastigmine in the Real World Dementia Clinics of the Okayama Rivastigmine Study (ORS), Journal of Alzheimer's Disease, 48(3) 757-763, 2015.10

    Kosuke Matsuzono, Kota Sato, Syoichiro Kono, Nozomi Hishikawa, Yasuyuki Ohta, Toru Yamashita, Kentaro Deguchi, Yumiko Nakano, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Polyneuritis and refractory headache overlap with synovitis, acne, pustulosis, hyperostosis and osteitis syndrome, NEUROLOGY AND CLINICAL NEUROSCIENCE, 3(5) 182-184, 2015.09

    Kosuke Matsuzono, Nozomi Hishikawa, Yasuyuki Ohta, Toru Yamashita, Kentaro Deguchi, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Burnout of Long-term Care Facility Employees: Relationship with Employees' Expressed Emotion Toward Patients, INTERNATIONAL JOURNAL OF GERONTOLOGY, 9(3) 161-165, 2015.09

    Koji Tanaka, Naoki Iso, Akira Sagari, Akiko Tokunaga, Ryoichiro Iwanaga, Sumihisa Honda, Hideyuki Nakane, Yasuyuki Ohta, Goro Tanaka

    Multiple Authorship (Including Foreigners)

  • Comprehensive clinical evaluations of frontotemporal dementia contrasting to Alzheimer's disease (oFTD Study), Journal of Alzheimer's Disease, 48(1) 279-286, 2015.08

    Kosuke Matsuzono, Nozomi Hishikawa, Toru Yamashita, Yasuyuki Ohta, Kota Sato, Shoichiro Kono, Kentaro Deguchi, Ryuta Morihara, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical Benefits of Memantine Treatment for Alzheimer's Disease in the Okayama Memantine Study II (OMS II), Journal of Alzheimer's Disease, 47(2) 487-493, 2015.07

    Kosuke Matsuzono, Toru Yamashita, Yasuyuki Ohta, Nozomi Hishikawa, Makoto Koike, Kota Sato, Syoichiro Kono, Kentaro Deguchi, Yumiko Nakano, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical benefits for older Alzheimer's disease patients: Okayama Late Dementia Study (OLDS), Journal of Alzheimer's Disease, 46(3) 687-693, 2015.06

    Kosuke Matsuzono, Toru Yamashita, Yasuyuki Ohta, Nozomi Hishikawa, Kota Sato, Syoichiro Kono, Kentaro Deguchi, Yumiko Nakano, Koji Abe

    Multiple Authorship (Including Foreigners)

  • 反復性けいれんを伴う重症脳炎に対するケトン療法の効果, 脳循環代謝, 26(1) 182, 2014.11

    松薗 構佑, 菱川 望, 太田 康之, 山下 徹, 出口 健太郎, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • 世界初の汎自律神経+知覚神経障害性プリオン病の遺伝子異常, 脳循環代謝, 26(1) 159, 2014.11

    松薗 構佑, 菱川 望, 太田 康之, 山下 徹, 出口 健太郎, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • 側頭葉内側萎縮と大脳白質病変の併存がアルツハイマー病患者の認知機能と情動機能に及ぼす影響, 脳循環代謝, 26(1) 214, 2014.11

    徳地 亮, 菱川 望, 佐藤 恒太, 幡中 典子, 武本 麻美, 福井 裕介, 太田 康之, 出口 健太郎, 山下 徹, 阿部 康二

    Multiple Authorship (Including Foreigners)

  • Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits., Acta Neuropathol Commun, 2(1) 37, 2014.01

    Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien JP

    Multiple Authorship (Including Foreigners)

  • Tumorigenesis of Induced Pluripotent Stem Cells in Ischemic Mouse Model, STROKE, 44(2) , 2013.02

    Koji Abe, Toru Yamashita, Hiromi Kawai, Fengfeng Tian, Yasuyuki Ohta

    Multiple Authorship (Including Foreigners)

  • Clinical Features and Molecular Pathogenesis of Asidan/SCA36: A Novel Spinocerebellar Ataxia with Motor Neuron Involvement, NEUROLOGY, 80 , 2013.02

    Yoshio Ikeda, Yasuyuki Ohta, Wentao Liu, Hatasu Kobayashi, Miyuki Okamoto, Kazuhiro Takamatsu, Taisei Ota, Yasuhiro Manabe, Koichi Okamoto, Akio Koizumi, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Cognitive and Affective Impairments of a Novel SCA/MND Crossroad Mutation Asidan, NEUROLOGY, 80 , 2013.02

    Koji Abe, Yoshio Ikeda, Tomoko Kurata, Yasuyuki Ohta, Yasuhiro Manabe, Miyuki Okamoto, Kazuhiro Takamatsu, Taisei Ota, Yoshiki Takao, Yoshihiko Shiro, Mikio Shoji, Tatsushi Kamiya, Hatasu Kobayashi, A...

    Multiple Authorship (Including Foreigners)

  • Acoustic impairment is a distinguishable clinical feature of Asidan/SCA36, Journal of the Neurological Sciences, 324(1-2) 109-112, 2013.01

    Yoshio Ikeda, Yasuyuki Ohta, Tomoko Kurata, Yoshihiko Shiro, Yoshiki Takao, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain, Journal of the Neurological Sciences, 322(1-2) 59-63, 2012.11

    Tomoko Kurata, Hiromi Kawai, Kazunori Miyazaki, Miki Kozuki, Nobutoshi Morimoto, Yasuyuki Ohta, Yoshio Ikeda, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical features of sca36: A novel spinocerebellar ataxia with motor neuron involvement (asidan), Neurology, 79(4) 333-341, 2012.07

    Yoshio Ikeda, Yasuyuki Ohta, Hatasu Kobayashi, Miyuki Okamoto, Kazuhiro Takamatsu, Taisei Ota, Yasuhiro Manabe, Koichi Okamoto, Akio Koizumi, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer's disease, Neurological Research, 34(6) 601-610, 2012.07

    Tomoko Kurata, Kazunori Miyazaki, Miki Kozuki, Nobutoshi Morimoto, Yasuyuki Ohta, Yoshio Ikeda, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Clinical and pathological improvement in stroke-prone spontaneous hypertensive rats related to the pleiotropic effect of cilostazol, Stroke, 43(6) 1639-1646, 2012.06

    Yoshio Omote, Kentaro Deguchi, Fengfeng Tian, Hiromi Kawai, Tomoko Kurata, Toru Yamashita, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • CSF flow dynamics in motor neuron disease, Neurological Research, 34(5) 512-517, 2012.06

    Kota Sato, Nobutoshi Morimoto, Tohru Matsuura, Yasuyuki Ohta, Masatoshi Tsunoda, Yoshio Ikeda, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Metabolic syndrome is a risk factor for acute cerebral infarction in a younger elderly Kurashiki population, Journal of Stroke and Cerebrovascular Diseases, 21(3) 231-239, 2012.04

    Yasuyuki Ohta, Yoshiki Takao, Kazuhiro Harada, Yasushi Takehisa, Takeo Takao, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Delayed Audiovisual Integration of Patients with Mild Cognitive Impairment and Alzheimer's Disease Compared with Normal Aged Controls, JOURNAL OF ALZHEIMERS DISEASE, 32(2) 317-328, 2012

    Jinglong Wu, Jiajia Yang, Yinghua Yu, Qi Li, Naoya Nakamura, Yong Shen, Yasuyuki Ohta, Shengyuan Yu, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Expression of Keap1-Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion, Brain Research, 1370 246-253, 2011.10

    Nobuhito Tanaka, Yoshio Ikeda, Yasuyuki Ohta, Kentaro Deguchi, Fengfeng Tian, Jingwei Shang, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis, Autophagy, 7(9) 985-992, 2011.09

    Feng Feng Tian, Nobutoshi Morimoto, Wen Tao Liu, Yasuyuki Ohta, Kentaro Deguchi, Kazunori Miyazaki, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Correlation of cerebral spinal fluid pH and HCO <inf>3</inf>- with disease progression in ALS, Journal of the Neurological Sciences, 307(1-2) 74-78, 2011.08

    Nobutoshi Morimoto, Kentaro Deguchi, Kota Sato, Taijun Yunoki, Shoko Deguchi, Yasuyuki Ohta, Tomoko Kurata, Yoshiki Takao, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Amlodipine and Atorvastatin Exert Protective and Additive Effects Via Antiapoptotic and Antiautophagic Mechanisms After Transient Middle Cerebral Artery Occlusion in Zucker Metabolic Syndrome Rats, JOURNAL OF NEUROSCIENCE RESEARCH, 89(8) 1228-1234, 2011.08

    Xuemei Zhang, Shoko Deguchi, Kentaro Deguchi, Yasuyuki Ohta, Toru Yamashita, Jingwei Shang, Fengfeng Tian, Ning Liu, Wentao Liu, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Neurological and pathological improvements of cerebral infarction in mice with platinum nanoparticles, Journal of Neuroscience Research, 89(7) 1125-1133, 2011.07

    Motonori Takamiya, Yusei Miyamoto, Toru Yamashita, Kentaro Deguchi, Yasuyuki Ohta, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Atorvastatin and pitavastatin protect cerebellar Purkinje cells in AD model mice and preserve the cytokines MCP-1 and TNF-α, Brain Research, 1388 32-38, 2011.05

    Miki Kozuki, Tomoko Kurata, Kazunori Miyazaki, Nobutoshi Morimoto, Yasuyuki Ohta, Yoshio Ikeda, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Comparisons of acoustic function in SCA31 and other forms of ataxias, Neurological Research, 33(4) 427-432, 2011.05

    Yoshio Ikeda, Makiko Nagai, Tomoko Kurata, Toru Yamashita, Yasuyuki Ohta, Shoko Nagotani, Kentaro Deguchi, Yasushi Takehisa, Yoshihiko Shiro, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis, Journal of Neuroscience Research, 89(5) 718-728, 2011.05

    Kazunori Miyazaki, Yasuyuki Ohta, Makiko Nagai, Nobutoshi Morimoto, Tomoko Kurata, Yasushi Takehisa, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat, Brain Research, 1382 308-314, 2011.03

    Hiromi Kawai, Shoko Deguchi, Kentaro Deguchi, Toru Yamashita, Yasuyuki Ohta, Yoshio Omote, Tomoko Kurata, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice, Brain Research, 1371 161-170, 2011.01

    Tomoko Kurata, Kazunori Miyazaki, Miki Kozuki, Violeta Lukic Panin, Nobutoshi Morimoto, Yasuyuki Ohta, Makiko Nagai, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Synergistic benefit of combined amlodipine plus atorvastatin on neuronal damage after stroke in Zucker metabolic rat, Brain Research, 1368 317-323, 2011.01

    Hiromi Kawai, Shoko Deguchi, Kentaro Deguchi, Toru Yamashita, Yasuyuki Ohta, Jingwei Shang, Fengfeng Tian, Xuemei Zhang, Ning Liu, Wentao Liu, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Strong neurogenesis, angiogenesis, synaptogenesis, and antifibrosis of hepatocyte growth factor in rats brain after transient middle cerebral artery occlusion, Journal of Neuroscience Research, 89(1) 86-95, 2011.01

    Jingwei Shang, Kentaro Deguchi, Yasuyuki Ohta, Ning Liu, Xuemei Zhang, Fengfeng Tian, Toru Yamashita, Yoshio Ikeda, Tohru Matsuura, Hiroshi Funakoshi, Toshikazu Nakamura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • PSP as distinguished from CBD, MSA-P and PD by clinical and imaging differences at an early stage, Internal Medicine, 50(22) 2775-2781, 2011

    Tomoko Kurata, Satsuki Kametaka, Yasuyuki Ohta, Nobutoshi Morimoto, Shoko Deguchi, Kentaro Deguchi, Yoshio Ikeda, Yoshiki Takao, Taisei Ohta, Yasuhiro Manabe, Shuhei Sato, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Tactile pattern delivery device to investigate cognitive mechanisms for early detection of Alzheimer's disease, Early Detection and Rehabilitation Technologies for Dementia: Neuroscience and Biomedical Applications, 89-97, 2011

    Jiajia Yang, Takashi Ogasa, Jinglong Wu, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Neuroprotective and Angiogenic Effects of Bone Marrow Transplantation Combined With Granulocyte Colony-Stimulating Factor in a Mouse Model of Amyotrophic Lateral Sclerosis., Cell medicine, 2(2) 69-83, 2011

    Yasuyuki Ohta, Makiko Nagai, Kazunori Miyazaki, Nobuhito Tanaka, Hiromi Kawai, Takafumi Mimoto, Nobutoshi Morimoto, Tomoko Kurata, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Tumorigenic Development of Induced Pluripotent Stem Cells in Ischemic Mouse Brain, CELL TRANSPLANTATION, 20(6) 883-891, 2011

    Toru Yamashita, Hiromi Kawai, Fengfeng Tian, Yasuyuki Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Neuroprotective and Angiogenic Effects of Bone Marrow Transplantation Combined With Granulocyte Colony-Stimulating Factor in a Mouse Model of Amyotrophic Lateral Sclerosis, CELL TRANSPLANTATION, 20(10) 1657, 2011

    Yasuyuki Ohta, Makiko Nagai, Kazunori Miyazaki, Nobuhito Tanaka, Hiromi Kawai, Takafumi Mimoto, Nobutoshi Morimoto, Tomoko Kurata, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • In vivo optical imaging of early-stage apoptosis in mouse brain after transient cerebral ischemia, Journal of Neuroscience Research, 88(16) 3488-3497, 2010.12

    Ning Liu, Kentaro Deguchi, Jingwei Shang, Xuemei Zhang, Fengfeng Tian, Toru Yamashita, Yasuyuki Ohta, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • In vivo imaging of autophagy in a mouse stroke model, Autophagy, 6(8) 1107-1114, 2010.11

    Feng Feng Tian, Kentaro Deguchi, Toru Yamashita, Yasuyuki Ohta, Nobutoshi Morimoto, Jingwei Shang, Xuemei Zhang, Ning Liu, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Antiapoptotic and antiautophagic effects of glial cell line-derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats, Journal of Neuroscience Research, 88(10) 2197-2206, 2010.08

    Jingwei Shang, Kentaro Deguchi, Toru Yamashita, Yasuyuki Ohta, Hanzhe Zhang, Nobutoshi Morimoto, Ning Liu, Xuemei Zhang, Fengfeng Tian, Tohru Matsuura, Hiroshi Funakoshi, Toshikazu Nakamura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Tridermal tumorigenesis of induced pluripotent stem cells transplanted in ischemic brain, Journal of Cerebral Blood Flow and Metabolism, 30(8) 1487-1493, 2010.08

    Hiromi Kawai, Toru Yamashita, Yasuyuki Ohta, Kentaro Deguchi, Shoko Nagotani, Xuemei Zhang, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Temporal and spatial differences of multiple protein expression in the ischemic penumbra after transient MCAO in rats, BRAIN RESEARCH, 1343 143-152, 2010.07

    Xuemei Zhang, Kentaro Deguchi, Toru Yamashita, Yasuyuki Ohta, Jingwei Shang, Fengfeng Tian, Ning Liu, Violeta Lukic Panin, Yoshio Ikeda, Tohru Matsuura, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Induction of Parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene, Journal of Neuroscience Research, 88(8) 1804-1811, 2010.06

    Nobutoshi Morimoto, Makiko Nagai, Kazunori Miyazaki, Yasuyuki Ohta, Tomoko Kurata, Yasushi Takehisa, Yoshio Ikeda, Tohru Matsuura, Masato Asanuma, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Decline of Human Tactile Angle Discrimination in Patients with Mild Cognitive Impairment and Alzheimer's Disease, JOURNAL OF ALZHEIMERS DISEASE, 22(1) 225-234, 2010

    Jiajia Yang, Takashi Ogasa, Yasuyuki Ohta, Koji Abe, Jinglong Wu

    Multiple Authorship (Including Foreigners)

  • Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation., Neurology international, 1(1) e16, 2009.11

    Hisashi Narai, Yasuhiro Manabe, Makiko Nagai, Isao Nagano, Yasuyuki Ohta, Tetsuro Murakami, Yasushi Takehisa, Tatsushi Kamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Changes of Nogo-A and receptor NgR in the lumbar spinal cord of ALS model mice, Neurological Research, 31(3) 316-321, 2009.04

    Kazunori Miyazaki, Makiko Nagai, Yasuyuki Ohta, Nobutoshi Morimoto, Tomoko Kurata, Tetsuro Murakami, Yasushi Takehisa, Yoshio Ikeda, Tatsushi Kamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Therapeutic Benefits of Intrathecal Protein Therapy in a Mouse Model of Amyotrophic Lateral Sclerosis, ANNALS OF NEUROLOGY, 66 S17, 2009

    Yasuyuki Ohta, Makiko Nagai, Nobutoshi Morimoto, Kazunori Miyazaki, Yasushi Takehisa, Yoshio Ikeda, Tohru Matsuura, Sadamitsu Asoh, Shigeo Ohra, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Efficacy of the free radical scavenger, edaravone, for motor palsy of acute lacunar infarction, Internal Medicine, 48(8) 593-596, 2009

    Yasuyuki Ohta, Kazuhiro Takamatsu, Tomoko Fukushima, Satomi Ikegami, Ikuko Takeda, Taisei Ota, Katsuya Goto, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Therapeutic Benefits of Intrathecal Protein Therapy in a Mouse Model of Amyotrophic Lateral Sclerosis, ANNALS OF NEUROLOGY, 66 S64, 2009

    Yasuyuki Ohta, Makiko Nagai, Nobutoshi Morimoto, Kazunori Miyazaki, Yasushi Takehisa, Yoshio Ikeda, Tohru Matsuura, Sadamitsu Asoh, Shigeo Ohta, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction, Neurological Research, 30(8) 860-867, 2008.10

    Tomoko Kurata, Takeshi Hayashi, Tetsuro Murakami, Kazunori Miyazaki, Nobutoshi Morimoto, Yasuyuki Ohta, Yasushi Takehisa, Makiko Nagai, Takeshi Kawarabayashi, Yoshiki Takao, Taisei Ohta, Yasuo Harigay...

    Multiple Authorship (Including Foreigners)

  • Efficacy of a free radical scavenger, edaravone, on acute lacunar infarction, STROKE, 39(2) 612, 2008.02

    Yasuyuki Ohta, Tomoko Fukushima, Kazuhiro Takamatsu, Satomi Ikegami, Ikuko Takeda, Taisei Ota, Katsuya Goto

    Multiple Authorship (Including Foreigners)

  • Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress, Brain Research, 1188(1) 1-8, 2008.01

    Kentaro Deguchi, Takeshi Hayashi, Shoko Nagotani, Yoshihide Sehara, Han Zhe Zhang, Atsushi Tsuchiya, Yasuyuki Ohta, Koji Tomiyama, Nobutoshi Morimoto, Masahiro Miyazaki, Nam ho Huh, Atsunori Nakao, Ta...

    Multiple Authorship (Including Foreigners)

  • Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis, Journal of Neuroscience Research, 86(13) 3028-3037, 2008

    Yasuyuki Ohta, Tatsushi Kamiya, Makiko Nagai, Tetsuya Nagata, Nobutoshi Morimoto, Kazunori Miyazaki, Tetsuro Murakami, Tomoko Kurata, Yasushi Takehisa, Yoshio Ikeda, Sadamitsu Asoh, Shigeo Ohta, Koji ...

    Multiple Authorship (Including Foreigners)

  • Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis, Neurological Research, 29(8) 767-771, 2007.12

    Tetsuya Nagata, Hristelina Ilieva, Tetsuro Murakami, Mito Shiote, Hisashi Narai, Yasuyuki Ohta, Takeshi Hayashi, Mikio Shoji, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Increased autophagy in transgenic mice with a G93A mutant SOD1 gene, Brain Research, 1167(1) 112-117, 2007.09

    Nobutoshi Morimoto, Makiko Nagai, Yasuyuki Ohta, Kazunori Miyazaki, Tomoko Kurata, Mizuki Morimoto, Tetsuro Murakami, Yasushi Takehisa, Yoshio Ikeda, Tatsushi Kamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene, Brain Research, 1150(1) 182-189, 2007.08

    Tetsuro Murakami, Makiko Nagai, Kazunori Miyazaki, Nobutoshi Morimoto, Yasuyuki Ohta, Tomoko Kurata, Yasushi Takehisa, Tatsushi Kamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant β-amyloid precursor protein and presenilin-1, Journal of Neuroscience Research, 85(10) 2246-2252, 2007.08

    Tomoko Kurata, Takeshi Kawarabayashi, Tetsuro Murakami, Kazunori Miyazaki, Nobutoshi Morimoto, Yasuyuki Ohta, Yasushi Takehisa, Makiko Nagai, Masaki Ikeda, Etsuro Matsubara, David Westaway, Peter St G...

    Multiple Authorship (Including Foreigners)

  • Two cases of spinocerebellar ataxia accompanied by involvement of the skeletal motor neuron system and bulbar palsy, Internal Medicine, 46(11) 751-756, 2007.06

    Yasuyuki Ohta, Takeshi Hayashi, Makiko Nagai, Miyuki Okamoto, Shoko Nagotani, Isao Nagano, Nobuhiko Ohmori, Yasushi Takehisa, Tetsuro Murakami, Mikio Shoji, Tatsushi Kamiya, Koji Abe

    Multiple Authorship (Including Foreigners)

  • PINK1, a gene product of PARK6, accumulates in α-synucleinopathy brains [3], Journal of Neurology, Neurosurgery and Psychiatry, 78(6) 653-655, 2007.06

    Tetsuro Murakami, Yasuhiro Moriwaki, Takeshi Kawarabayashi, Makiko Nagai, Yasuyuki Ohta, Kentaro Deguchi, Tomoko Kurata, Nobutoshi Morimoto, Yasushi Takehisa, Etsuro Matsubara, Masaki Ikeda, Yasuo Har...

    Multiple Authorship (Including Foreigners)

  • Granulocytic sarcoma with orbit, caude equina, muscle and peripheral nerve extension but without bone marrow involvement, Internal Medicine, 46(9) 633-635, 2007.05

    Yasuhiro Manabe, Yoshiyuki Hamakawa, Kazutaka Sunami, Yasuyuki Ohta, Nobuhiko Omori, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene, Journal of Neuroscience Research, 84(5) 980-992, 2006.10

    Yasuyuki Ohta, Makiko Nagai, Tetsuya Nagata, Tetsuro Murakarni, Isao Nagano, Hisashi Narai, Tomoko Kurata, Mito Shiote, Mikio Shoji, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Nonparaneoplastic limbic encephalitis with relapsing polychondritis, Journal of the Neurological Sciences, 220(1-2) 85-88, 2004.05

    Yasuyuki Ohta, Isao Nagano, Daigo Niiya, Hideki Fujioka, Takumi Kishimoto, Mikio Shoji, Koji Abe

    Multiple Authorship (Including Foreigners)

  • Cauda equina syndrome caused by idiopathic sacral epidural lipomatosis, Internal Medicine, 41(7) 593-594, 2002

    Yasuyuki Ohta, Takeshi Hayashi, Chihoko Sasaki, Mito Shiote, Yasuhiro Manabe, Mikio Shoji, Koji Abe

    Multiple Authorship (Including Foreigners)

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Other external funds procured

  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B),2017.04 - 2020.03,Development of next-generation therapy based on comprehensive molecular pathology of neurodegenerative diseases

    Japan Society for the Promotion of Science

  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C),2017.04 - 2020.03,Evaluation of the role of new disease modifier variant chromogranin B in the common molecular pathology of neurodegenerative diseases

    Japan Society for the Promotion of Science

  • Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C),2015.04 - 2018.03,Development of new theraphy of brain protection, dementia prevention and neuroregeneration focusing on astrocytes in cerebral infarction

    In this study, we focused on the role of astrocytes in hypoxia and oxidative stress of cerebral infarction, and analyzed it using mouse focal cerebral ischemia model. Immunohistochemistry of cerebral tissue sections showed remarkable increased expression of HIF1α, a hypoxic stress marker, around the cerebral infarction lesions 12 hours after the cerebral infarction, and the highest expression of GSH, antioxidant stress marker, 72 hours after the onset of cerebral infarction. In vivo imaging and on immunohistochemical analyses, the expression of Nrf2, an oxidative stress marker, peaked after 24 hours, and Nrf2 was expressed in both neurons and astrocytes. This study suggested that hypoxic stress was first involved in cerebral infarction, then oxidative stress was involved, in which astrocyte acted mainly.

    Japan Society for the Promotion of Science

Past consigned research fund received

  • Development of next-generation therapy based on comprehensive molecular pathology of neurodegenerative diseases, 2017.04 - 2020.03, General Consignment Study

  • Evaluation of the role of new disease modifier variant chromogranin B in the common molecular pathology of neurodegenerative diseases, 2017.04 - 2020.03, General Consignment Study

  • Development of new theraphy of brain protection, dementia prevention and neuroregeneration focusing on astrocytes in cerebral infarction, 2015.04 - 2018.03, General Consignment Study