Predicting anterior cruciate ligament degeneration using magnetic resonance imaging: Insights from histological evaluation, JOURNAL OF ORTHOPAEDIC SCIENCE, 30(2) 325-332, 2025.03

Toyono, S; Suzuki, A; Wanezaki, Y; Takahara, D; Ohe, R; Fukushima, S; Futakuchi, M; Takagi, M

Single Author

BRCA1-binding factor deficiency induces tumorigenesis dependent on estrogen-regulated centrosome amplification, CANCER SCIENCE, 116 1275, 2025.01

Chiba, N; Ogoh, H; Iichi, Y; Sasaki, T; Yoshida, T; Ichimura, S; Fang, ZZ; Li, XM; Futakuchi, M; Nakamura, Y; Watanabe, T; Yoshino, Y

Single Author

Effusion Reduction after Early Trastuzumab Deruxtecan Therapy for Unresectable HER2-Low Breast Cancer in an Older Patient: A Case Report, SURGICAL CASE REPORTS, 11(1) n/a, 2025

Akabane, A; Kawai, M; Suzuki, K; Goto, A; Tanaka, T; Futakuchi, M; Motoi, F

Single Author

Quantification of Gremlin 1 throughout the tumor stroma using whole slide imaging and its clinicopathological significance in gastric cancer, VIRCHOWS ARCHIV, 485(6) 1107-1116, 2024.12

Kitaoka, T; Harada, K; Sakashita, S; Kojima, M; Taki, T; Kuwata, T; Kinoshita, T; Futakuchi, M; Ishii, G; Sakamoto, N

Single Author

増大特集 学術研究支援の最先端 Ⅱ.先端モデル動物支援プラットフォーム(AdAMS) ⅱ.病理形態解析支援 腫瘍間質相互作用の組織学的空間解析, 生体の科学, 75(5) 440-441, 2024.10

大江 倫太郎, 二口 充

Single Author

Activation of fibroblasts by plasma cells via PDGF/PDGFR signaling in IgG4-related sialadenitis(タイトル和訳中), Journal of Clinical and Experimental Hematopathology, 64(3) 223-231, 2024.09

Kitaoka Takumi, Ohe Rintaro, Kabasawa Takanobu, Kaneko Masayuki, Sasahara Nobuyuki, Kono Michihisa, Suzuki Kazushi, Uchiyama Naoya, Ogawa Rinako, Futakuchi Mitsuru

Single Author

Knockout of Brca1-interacting factor Ola1 in female mice induces tumors with estrogen suppressible centrosome amplification, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1870(5) 167138, 2024.06

Yoshino, Y; Ogoh, H; Iichi, Y; Sasaki, T; Yoshida, T; Ichimura, S; Nakayama, M; Xi, W; Fujita, H; Kikuchi, M; Fang, ZZ; Li, XM; Abe, T; Futakuchi, M; Nakamura, Y; Watanabe, T; Chiba, N

Single Author

Lysophospholipid Acyltransferase 9 Promotes Emphysema Formation via Platelet-activating Factor, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 70(6) 482-492, 2024.06

Murano, H; Inoue, S; Hashidate-Yoshida, T; Shindou, H; Shimizu, T; Otaki, Y; Minegishi, Y; Kitaoka, T; Futakuchi, M; Igarashi, A; Nishiwaki, M; Nemoto, T; Sato, M; Kobayashi, M; Sato, K; Hanawa, T; Mi...

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area, CANCER CELL INTERNATIONAL, 24(1) 107, 2024.03

Ichiro Kawamura, Rintaro Ohe, Kazushi Suzuki, Takanobu Kabasawa, Takumi Kitaoka, Daiichiro Takahara, Michihisa Kono, Naoya Uchiyama, Hiroaki Musha, Mitsuru Futakuchi, Fuyuhiko Motoi

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area., Cancer cell international, 24(1) 107, 2024.03

Kawamura I, Ohe R, Suzuki K, Kabasawa T, Kitaoka T, Takahara D, Kono M, Uchiyama N, Musha H, Futakuchi M, Motoi F

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area., Cancer cell international, 24(1) 107, 2024.03

Ichiro Kawamura, Rintaro Ohe, Kazushi Suzuki, Takanobu Kabasawa, Takumi Kitaoka, Daiichiro Takahara, Michihisa Kono, Naoya Uchiyama, Hiroaki Musha, Mitsuru Futakuchi, Fuyuhiko Motoi

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area., Cancer cell international, 24(1) 107, 2024.03

Kawamura I, Ohe R, Suzuki K, Kabasawa T, Kitaoka T, Takahara D, Kono M, Uchiyama N, Musha H, Futakuchi M, Motoi F

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area, CANCER CELL INTERNATIONAL, 24(1) , 2024.03

Kawamura, I; Ohe, R; Suzuki, K; Kabasawa, T; Kitaoka, T; Takahara, D; Kono, M; Uchiyama, N; Musha, H; Futakuchi, M; Motoi, F

Single Author

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area, CANCER CELL INTERNATIONAL, 24(1) , 2024.03

Kawamura, I; Ohe, R; Suzuki, K; Kabasawa, T; Kitaoka, T; Takahara, D; Kono, M; Uchiyama, N; Musha, H; Futakuchi, M; Motoi, F

Single Author

Involvement of TAMs on tumor growth in the lymph node microenvironment but not in primary site, CANCER SCIENCE, 115 846, 2024.03

Takanobu Kabasawa, Rintaro Ohe, Kazushi Suzuki, Takumi Kitaoka, Mitsuru Futakuchi

Single Author

Involvement of TAMs on tumor growth in the lymph node microenvironment but not in primary site, CANCER SCIENCE, 115 846, 2024.03

Kabasawa, T; Ohe, R; Suzuki, K; Kitaoka, T; Futakuchi, M

Single Author

Histological spatial analysis on the induction of PD-L1+macrophages by CD8+T cells of triple-negative breast cancer, CANCER SCIENCE, 115 1588, 2024.03

Takumi Kitaoka, Kazushi Suzuki, Takanobu Kabasawa, Rintaro Ohe, Mitsuru Futakuchi

Single Author

Histological spatial analysis on the induction of PD-L1+macrophages by CD8+T cells of triple-negative breast cancer, CANCER SCIENCE, 115 1588, 2024.03

Kitaoka, T; Suzuki, K; Kabasawa, T; Ohe, R; Futakuchi, M

Single Author

Resident memory T cell contributes to the phenotype of inflammatory vitiligo, JOURNAL OF DERMATOLOGICAL SCIENCE, 113(2) 74-76, 2024.02

Okamura, K; Kabasawa, T; Saito, T; Arai, Y; Futakuchi, M; Suzuki, T

Single Author

BRCA1結合分子の欠損はエストロゲンで制御される中心体増幅に依存した悪性化を示す腫瘍を誘導する, 日本癌学会学術総会抄録集(Web), 83rd 1275, 2024

千葉奈津子, 小河穂波, 飯地雄大, 佐々木伯大, 吉田貴大, 市村志織, 方震宙, 李星明, 二口充, 中村保宏, 渡邊利雄, 吉野優樹

Single Author

Association of ADC of hyperintense lesions on FLAIR images with TERT promoter mutation status in glioblastoma IDH wild type., Surgical neurology international, 15 108, 2024

Kamimura S, Mitobe Y, Nakamura K, Matsuda K, Kanemura Y, Kanoto M, Futakuchi M, Sonoda Y

Single Author

Activation of fibroblasts by plasma cells via PDGF/PDGFR signaling in IgG4-related sialadenitis, JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY, 64(3) 223-231, 2024

Kitaoka, T; Ohe, R; Kabasawa, T; Kaneko, M; Sasahara, N; Kono, M; Suzuki, K; Uchiyama, N; Ogawa, R; Futakuchi, M

Single Author

Treatment Experience of Chemotherapy and Carbon-Ion Radiotherapy followed by Curative Conversion Surgery for Initially Locally Advanced Unresectable Pancreatic Cancer after Distal Gastrectomy, 癌と化学療法, 50(13) 1959-1961, 2023.12

渡邊大史, 菅原秀一郎, 高橋良輔, 安次富裕哉, 川城壮平, 佐藤啓, 根本健二, 河野通久, 二口充, 元井冬彦

Single Author

トリプルネガティブ乳癌の辺縁部微小環境のCD8陽性T細胞によるPD-L1陽性マクロファージの誘導に関する組織学的空間的解析(Histological spatial analysis on the induction of PD-L1+ macrophages by CD8+T cells at the marginal microenvironment of triple-negative breast cancer), Breast Cancer, 30(6) 1094-1104, 2023.11

Suzuki Kazushi, Ohe Rintaro, Kabasawa Takanobu, Kitaoka Takumi, Kawai Masaaki, Motoi Fuyuhiko, Futakuchi Mitsuru

Single Author

Histological spatial analysis on the induction of PD-L1<SUP>+</SUP> macrophages by CD8<SUP>+</SUP> T cells at the marginal microenvironment of triple-negative breast cancer, BREAST CANCER, 30(6) 1094-1104, 2023.11

Suzuki, K; Ohe, R; Kabasawa, T; Kitaoka, T; Kawai, M; Motoi, F; Futakuchi, M

Single Author

Targeting c-Jun Is a Potential Therapy for Luminal Breast Cancer Bone Metastasis, MOLECULAR CANCER RESEARCH, 21(9) 908-921, 2023.09

Han, YX; Katayama, S; Futakuchi, M; Nakamichi, K; Wakabayashi, Y; Sakamoto, M; Nakayama, J; Semba, K

Single Author

Identification of tumor-related genes via RNA sequencing of tumor tissues in<i> Xenopus tropicalis</i>, SCIENTIFIC REPORTS, 13(1) , 2023.08

Kitamura, K; Yamamoto, T; Ochi, H; Suzuki, M; Suzuki, N; Igawa, T; Yoshida, T; Futakuchi, M; Ogino, H; Michiue, T

Single Author

A durable complete response resulting from treatment with nivolumab plus ipilimumab for metastatic collecting duct carcinoma of the kidney, ASIAN JOURNAL OF UROLOGY, 10(3) 376-378, 2023.07

Funajima, K; Naito, S; Kabasawa, T; Nishida, H; Kato, T; Futakuchi, M; Tsuchiya, N

Single Author

In vivo [<SUP>18</SUP>F]THK-5351 imaging detected reactive astrogliosis in argyrophilic grain disease with comorbid pathology: A clinicopathological study, JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 82(5) 427-437, 2023.04

Kobayashi, R; Nakamura, T; Naganuma, F; Harada, R; Morioka, D; Kanoto, M; Furumoto, S; Kudo, Y; Kabasawa, T; Otani, K; Futakuchi, M; Kawakatsu, S; Okamura, N

Single Author

Regular protocol liver biopsy is useful to adjust immunosuppressant dose after adult liver transplantation, CLINICAL TRANSPLANTATION, 37(3) , 2023.03

Narita, S; Miuma, S; Okudaira, S; Koga, Y; Fukushima, M; Sasaki, R; Haraguchi, M; Soyama, A; Hidaka, M; Miyaaki, H; Futakuchi, M; Nagai, K; Ichikawa, T; Eguchi, S; Nakao, K

Single Author

意味性認知症の臨床病理学的多様性　早発性と晩発性、左側側頭葉萎縮と右側側頭葉萎縮、TDPタイプAとTDPタイプC病理の比較検討(Neuropathology Case Cluster: Neuropathology of focal cortical, behavioral, and psychiatric syndromes in neurodegenerative diseases　Clinicopathological diversity of semantic dementia: Comparisons of patients with early-onset versus late-onset, left-sided versus right-sided temporal atrophy, and TDP-type A versus type C pathology), NEUROPATHOLOGY, 43(1) 5-26, 2023.02

Kawakatsu Shinobu, Kobayashi Ryota, Morioka Daichi, Hayashi Hiroshi, Utsunomiya Aya, Kabasawa Takanobu, Ohe Rintaro, Futakuchi Mitsuru, Otani Koichi

Single Author

Potential role of M2 TAMs around lymphatic vessels during lymphatic invasion of papillary thyroid carcinoma, CANCER SCIENCE, 114 575, 2023.02

Takanobu Kabasawa, Rintaro Ohe, Mitsuru Futakuchi

Single Author

Induction of heterogeneity of chemo-resistance by the interaction between colorectal cancer cells and TAMs, CANCER SCIENCE, 114 1783, 2023.02

Junichi Goto, Rintaro Ohe, Takanobu Kabasawa, Mitsuru Futakuchi

Single Author

Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines, CANCER SCIENCE, 114 237, 2023.02

Yuxuan Han, Jun Nakayama, Mitsuru Futakuchi, Emi Ito, Shinya Watanabe, Kentaro Semba

Single Author

Clinicopathological diversity of semantic dementia: Comparisons of patients with early-onset versus late-onset, left-sided versus right-sided temporal atrophy, and TDP-type A versus type C pathology, NEUROPATHOLOGY, 43(1) 5-26, 2023.02

Kawakatsu, S; Kobayashi, R; Morioka, D; Hayashi, H; Utsunomiya, A; Kabasawa, T; Ohe, R; Futakuchi, M; Otani, K

Single Author

Induction of heterogeneity of chemo-resistance by the interaction between colorectal cancer cells and TAMs, CANCER SCIENCE, 114 1783, 2023.02

Goto, J; Ohe, R; Kabasawa, T; Futakuchi, M

Single Author

Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines, CANCER SCIENCE, 114 237, 2023.02

Han, YX; Nakayama, J; Futakuchi, M; Ito, E; Watanabe, S; Semba, K

Single Author

Potential role of M2 TAMs around lymphatic vessels during lymphatic invasion of papillary thyroid carcinoma, CANCER SCIENCE, 114 575, 2023.02

Kabasawa, T; Ohe, R; Futakuchi, M

Single Author

幽門側胃切除後局所進行切除不能膵癌に対し重粒子線併用化学療法後根治切除を得た1例, 癌と化学療法, 50 1959-1961, 2023

二口 充, 元井 冬彦

Single Author

Oncogenic isoform switch of tumor suppressor BCL11B in adult T-cell leukemia/lymphoma, EXPERIMENTAL HEMATOLOGY, 111 41-49, 2022.07

Permatasari, HK; Nakahata, S; Ichikawa, T; Fauzi, YR; Kiyonari, H; Shide, K; Kameda, T; Shimoda, K; Ono, M; Taki, T; Taniwaki, M; Futakuchi, M; Morishita, K

Single Author

Exploratory analysis on crosstalk between intra-tumor immunity and FGF/FGFR pathway in clear cell renal cell carcinoma., JOURNAL OF CLINICAL ONCOLOGY, 40(16) E16525, 2022.06

Narisawa, T; Naito, S; Mitsuda, Y; Oe, R; Sato, H; Kobayashi, C; Fukuda, M; Kitaoka, T; Miyano, Y; Ito, H; Kimura, M; Hamaguchi, M; Aoshima, K; Futakuchi, M; Tsuchiya, N

Single Author

The Utility and Safety of Liquid-Based Cytology in the Diagnosis of Intraocular Lymphoma, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 63(7) , 2022.06

Kaneko, Y; Ohe, R; Futakuchi, M; Nishitsuka, K

Single Author

Pathogenesis of follicular thymic hyperplasia associated with rheumatoid arthritis, PATHOLOGY INTERNATIONAL, 72(4) 252-260, 2022.04

Ohe, R; Yang, SR; Yamashita, D; Ichikawa, C; Saito, A; Kabasawa, T; Utsunomiya, A; Aung, NY; Urano, Y; Kitaoka, T; Suzuki, K; Takahara, D; Sasaki, A; Takakubo, Y; Takagi, M; Yamakawa, M; Futakuchi, M

Single Author

Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines, CANCER SCIENCE, 113 675, 2022.02

Han, YX; Nakayama, J; Futakuchi, M; Ito, E; Watanabe, S; Semba, K

Single Author

Establishment of Predicting Druggable Genes by Using Micro-specimens in gastric and colorectal cancers, CANCER SCIENCE, 113 460, 2022.02

Ohe, R; Kabasawa, T; Futakuchi, M

Single Author

Utility of Liquid-Based Cytology and Cell Block Procedure Obtained by Vitrectomy to Diagnose Ocular Sarcoidosis-The Significance of Epithelioid Granuloma and Epithelioid Cells, CLINICAL OPHTHALMOLOGY, 16 3289-3296, 2022

Ohe, R; Kaneko, Y; Namba, H; Nishi, K; Goto, JI; Futakuchi, M; Nishitsuka, K

Single Author

Pulmonary atherosclerosis in a patient with chronic thromboembolic pulmonary hypertension, PATHOLOGY INTERNATIONAL, 71(2) 164-166, 2021.02

Furukawa, K; Kawano, H; Futakuchi, M; Ishijima, M; Yamgataga, Y; Ueno, Y; Koga, S; Ikeda, S; Eishi, K; Maemura, K

Single Author

Myocardial Damage and Microvasculopathy in a Patient With Systemic Sclerosis, CIRCULATION JOURNAL, 85(2) 224, 2021.02

Kawano, H; Kudo, T; Umeda, M; Futakuchi, M; Sueyoshi, E; Maemura, K

Single Author

Effects of OPG on Osteolysis, Proliferation of Mammary Cancer Cells and Induction of CSCs in the Bone Microenvironment., CANCER SCIENCE, 112 541, 2021.02

Futakuchi, M; Tachibana, Y; Kris, L; Furukawa, M; Fukuoka, J

Single Author

The Effects of TGFβ Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment, CANCER SCIENCE, 112 348, 2021.02

Futakuchi, M; Tachibana, Y; Kris, L; Furukawa, M; Fukuoka, J

Single Author

Novel tumor suppressor gene NDRG2 deficiency promotes metabolic disorders and liver cancer development, CANCER SCIENCE, 112 374, 2021.02

Ichikawa, T; Nakahata, S; Futakuchi, M; Yamaguchi, R; Morishita, K

Single Author

Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intracaudal arterial injection (vol 25, pg 111, 2020), GENES TO CELLS, 25(5) 358, 2020.05

Han, Y; Nakayama, J; Hayashi, Y; Jeong, S; Futakuchi, M; Ito, E; Semba, K

Single Author

Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intracaudal arterial injection, GENES TO CELLS, 25(2) 111-123, 2020.02

Han, YX; Nakayama, J; Hayashi, Y; Jeong, S; Futakuchi, M; Ito, E; Watanabe, S; Semba, K

Single Author

Inferior Vena Cava Anomalies with Portal Vein System Continuation Presenting as Portal Hypertension with a Long-term Follow-up, INTERNAL MEDICINE, 59(22) 2897-2901, 2020

Fukushima, M; Miyaaki, H; Sasaki, R; Haraguchi, M; Miuma, S; Ishimaru, H; Hidaka, M; Okudaira, S; Eguchi, S; Futakuchi, M; Kusano, H; Kage, M; Nakao, K

Single Author

Detection of Lung Cancer Lymph Node Metastases from Whole-Slide Histopathologic Images Using a Two-Step Deep Learning Approach, AMERICAN JOURNAL OF PATHOLOGY, 189(12) 2428-2439, 2019.12

Pham, HHN; Futakuchi, M; Bychkov, A; Furukawa, T; Kuroda, K; Fukuoka, J

Single Author

The Effects of TGF-β Signaling on Cancer Cells and Cancer Stem Cells in the Bone Microenvironment, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(20) , 2019.10

Futakuchi, M; Lami, K; Tachibana, Y; Yamamoto, Y; Furukawa, M; Fukuoka, J

Single Author

Cancer-Associated Fibroblasts Enhance Survival and Progression of the Aggressive Pancreatic Tumor Via FGF-2 and CXCL8, CANCER MICROENVIRONMENT, 12(1) 37-46, 2019.04

Awaji, M; Futakuchi, M; Heavican, T; Iqbal, J; Singh, RK

Single Author

Evaluation of a biomarker for the diagnosis of pancreas cancer using an animal model, JOURNAL OF TOXICOLOGIC PATHOLOGY, 32(3) 135-141, 2019

Fukamachi, K; Hagiwara, Y; Futakuchi, M; Alexander, DB; Tsuda, H; Suzui, M

Single Author

Mechanisms of induction of cancer stem cells in the bone microenvironment; involvement of drug resistance, CANCER SCIENCE, 109 183, 2018.12

Futakuchi, M

Single Author

Persistent Pleural Lesions and Inflammation by Pulmonary Exposure of Multiwalled Carbon Nanotubes, CHEMICAL RESEARCH IN TOXICOLOGY, 31(10) 1025-1031, 2018.10

Liao, DP; Wang, QQ; He, JL; Alexander, DB; Abdelgied, M; El-Gazzar, AM; Futakuchi, M; Suzui, M; Kanno, J; Hirose, A; Xu, JG; Tsuda, H

Single Author

Therapeutic and Preventive Effects of Osteoclastogenesis Inhibitory Factor on Osteolysis, Proliferation of Mammary Tumor Cell and Induction of Cancer Stem Cells in the Bone Microenvironment, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(3) , 2018.03

Futakuchi, M; Nitanda, T; Ando, S; Matsumoto, H; Yoshimoto, E; Fukamachi, K; Suzui, M

Single Author

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(9) 2204-2209, 2018.02

Hashimoto, K; Ochi, H; Sunamura, S; Kosaka, N; Mabuchi, Y; Fukuda, T; Yao, K; Kanda, H; Ae, K; Okawa, A; Akazawa, C; Ochiya, T; Futakuchi, M; Takeda, S; Sato, S

Single Author

Growth inhibition of the crude extracts of the leaves of Musa basjoo in human colon cancer cells, CANCER SCIENCE, 109 775, 2018.01

Matsumoto, H; Ando, S; Fukamachi, K; Futakuchi, M; Suzui, M

Single Author

In vitro and vivo anticancer activity of a novel agent palmitoyl piperidinopiperidine, CANCER SCIENCE, 109 377, 2018.01

Ando, S; Matsumoto, H; Fukamachi, K; Futakuchi, M; Suzui, M

Single Author

Analysis of molecular mechanisms for tumor development and metastasis through a novel tumor suppressor gene NDRG2, CANCER SCIENCE, 109 67, 2018.01

Ichikawa, T; Tamura, T; Nakahata, S; Futakuchi, M; Morishita, K

Single Author

Ferric nitrilotriacetate induced renal tumorigenesis in MUTYH deficient mice, CANCER SCIENCE, 109 167, 2018.01

Akatsuka, S; Li, GH; Sakumi, K; Nakabeppu, Y; Futakuchi, M; Suzuki, H; Toyokuni, S

Single Author

Identification and Functional analysis of HNF1B as a multi-organ metastasis inducing gene, CANCER SCIENCE, 109 874, 2018.01

Nakayama, J; Matsui, A; Fujimoto, J; Futakuchi, M; Ito, E; Watanabe, S; Semba, K

Single Author

Cancer cell-derived microRNA induces osteoblastic phenotype in bone metastasis microenvironment., JOURNAL OF BONE AND MINERAL RESEARCH, 32 S64-S65, 2017.12

Hashimoto, K; Sunamura, S; Ochi, H; Fukuda, T; Okawa, A; Futakuchi, M; Takeda, S; Sato, S

Single Author

Fenton reaction-induced renal carcinogenesis in <i>Mutyh</i>-deficient mice exhibits less chromosomal aberrations than the rat model, PATHOLOGY INTERNATIONAL, 67(11) 564-574, 2017.11

Li, GH; Akatsuka, S; Chew, SH; Jiang, L; Nishiyama, T; Sakamoto, A; Takahashi, T; Futakuchi, M; Suzuki, H; Sakumi, K; Nakabeppu, Y; Toyokuni, S

Single Author

Growth inhibition of the crude extracts of <i>Musa basjoo</i> in human colon carcinoma cells, CANCER RESEARCH, 77 , 2017.07

Matsumoto, H; Ando, S; Fukamachi, K; Futakuchi, M; Kimura, K; Yoshimi, N; Suzui, M

Single Author

A new anticancer agent derived from decenoic acid for the treatment of colon cancer, CANCER RESEARCH, 77 , 2017.07

Suzui, M; Ando, S; Matsumoto, H; Fukamachi, K; Futakuchi, M; Yoshimi, N

Single Author

Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential, CANCER RESEARCH, 77(9) 2363-2374, 2017.05

Tamura, T; Ichikawa, T; Nakahata, S; Kondo, Y; Tagawa, Y; Yamamoto, K; Nagai, K; Baba, T; Yamaguchi, R; Futakuchi, M; Yamashita, Y; Morishita, K

Single Author

A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth <i>in vivo</i>, SCIENTIFIC REPORTS, 7 , 2017.01

Kawada, M; Inoue, H; Kajikawa, M; Sugiura, M; Sakamoto, S; Urano, S; Karasawa, C; Usami, I; Futakuchi, M; Masuda, T

Single Author

Mechanism of action of a novel anti-tumor antibody, anti-CXADR 6G10A, EUROPEAN JOURNAL OF CANCER, 69 S38, 2016.12

Kawada, M; Inoue, H; Kajikawa, M; Sugiura, M; Sakamoto, S; Urano, S; Karasawa, C; Usami, I; Futakuchi, M

Single Author

Development of a mechanism based short-term assay protocol to test carcinogenicity of multiple wall carbon nanotubes (MWNCTs) in the rat, TOXICOLOGY LETTERS, 259 S22, 2016.10

Tsuda, H; Alexander, DB; Alexander, WT; Abd Elgied, M; Elgazzar, A; Xu, J; Numano, T; Suzui, M; Futakuchi, M; Fukamachi, K; Hirose, A; Kanno, J

Single Author

Suppression of C5a decreases ischemia/reperfusion injury and increases proliferation of epithelial cells in the rat small intestine, IMMUNOBIOLOGY, 221(10) 1146, 2016.10

Tuboly, E; Futakuchi, M; Varga, G; Érces, D; Mészáros, A; Kisvári, G; Boros, M; Okada, H; Okada, N

Single Author

Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors, CANCER SCIENCE, 107(7) 924-935, 2016.07

Suzui, M; Futakuchi, M; Fukamachi, K; Numano, T; Abdelgied, M; Takahashi, S; Ohnishi, M; Omori, T; Tsuruoka, S; Hirose, A; Kanno, J; Sakamoto, Y; Alexander, DB; Alexander, WT; Xu, JG; Tsuda, H

Single Author

Heterogeneity of tumor cells in the bone microenvironment: Mechanisms and therapeutic targets for bone metastasis of prostate or breast cancer, ADVANCED DRUG DELIVERY REVIEWS, 99 206-211, 2016.04

Futakuchi, M; Fukamachi, K; Suzui, M

Single Author

C5a inhibitor protects against ischemia/reperfusion injury in rat small intestine, MICROBIOLOGY AND IMMUNOLOGY, 60(1) 35-46, 2016.01

Tuboly, E; Futakuchi, M; Varga, G; Erces, D; Tokés, T; Mészáros, A; Kaszaki, J; Suzui, M; Imai, M; Okada, A; Okada, N; Boros, M; Okada, H

Single Author

Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study, CANCER SCIENCE, 106(7) 825-832, 2015.07

Xu, JG; Alexander, DB; Iigo, M; Hamano, H; Takahashi, S; Yokoyama, T; Kato, M; Usami, I; Tokuyama, T; Tsutsumi, M; Tamura, M; Oguri, T; Niimi, A; Hayashi, Y; Yokoyama, Y; Tonegawa, K; Fukamachi, K; Fu...

Single Author

Murine Herc6 Plays a Critical Role in Protein ISGylation <i>In Vivo</i> and Has an ISGylation-Independent Function in Seminal Vesicles, JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 35(5) 351-358, 2015.05

Arimoto, K; Hishiki, T; Kiyonari, H; Abe, T; Cheng, CY; Yan, M; Fan, JB; Futakuchi, M; Tsuda, H; Murakami, Y; Suzuki, H; Zhang, DE; Shimotohno, K

Single Author

<i>In vivo</i> <SUP>18</SUP>F-fluorodeoxyglucose-positron emission tomography/computed tomography imaging of pancreatic tumors in a transgenic rat model carrying the human <i>KRAS<SUP>G12V</SUP></i> oncogene, ONCOLOGY LETTERS, 9(5) 2112-2118, 2015.05

Shibata, K; Fukamachi, K; Tsuji, A; Saga, T; Futakuchi, M; Nagino, M; Tsuda, H; Suzui, M

Single Author

Rat N-ERC/Mesothelin as a Marker for <i>In Vivo</i> Screening of Drugs against Pancreas Cancer, PLOS ONE, 9(10) , 2014.10

Fukamachi, K; Iigo, M; Hagiwara, Y; Shibata, K; Futakuchi, M; Alexander, DB; Hino, O; Suzui, M; Tsuda, H

Single Author

Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine, BIOMETALS, 27(5) 1017-1029, 2014.10

Iigo, M; Alexander, DB; Xu, JG; Futakuchi, M; Suzui, M; Kozu, T; Akasu, T; Saito, D; Kakizoe, T; Yamauchi, K; Abe, F; Takase, M; Sekine, K; Tsuda, H

Single Author

Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes, CANCER SCIENCE, 105(7) 763-769, 2014.07

Xu, JG; Alexander, DB; Futakuchi, M; Numano, T; Fukamachi, K; Suzui, M; Omori, T; Kanno, J; Hirose, A; Tsuda, H

Single Author

A Novel Transgenic Mouse Model Carrying Human Tribbles Related Protein 3 (TRB3) Gene and Its Site Specific Phenotype, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 37(6) 1068-1074, 2014.06

Sakai, Y; Fukamachi, K; Futakuchi, M; Miyoshi, I; Tsuda, H; Suzui, M; Hayashi, H

Single Author

Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles, ARCHIVES OF TOXICOLOGY, 88(1) 65-75, 2014.01

Xu, JG; Futakuchi, M; Alexander, DB; Fukamachi, K; Numano, T; Suzui, M; Shimizu, H; Omori, T; Kanno, J; Hirose, A; Tsuda, H

Single Author

Comparative Study of Toxic Effects of Anatase and Rutile Type Nanosized Titanium Dioxide Particles <i>in vivo</i> and <i>in vitro</i>, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 15(2) 929-935, 2014

Numano, T; Xu, JG; Futakuchi, M; Fukamachi, K; Alexander, DB; Furukawa, F; Kanno, J; Hirose, A; Tsuda, H; Suzui, M

Single Author

Promotive effects of cell proliferation and chromosomal instability induced by tribbles-related protein 3 in mouse mammary tumor cells, ONCOLOGY REPORTS, 30(1) 64-70, 2013.07

Sakai, Y; Fukamachi, K; Futakuchi, M; Hayashi, H; Suzui, M

Single Author

Animal model for mammary tumor growth in the bone microenvironment, BREAST CANCER, 20(3) 195-203, 2013.07

Futakuchi, M; Singh, RK

Single Author

Evaluation of carcinogenic effect of multiwall carbon nanotubes on the rat lung at 2 and 52 weeks after pulmonary instillation, CANCER RESEARCH, 73(8) , 2013.04

Suzui, M; Numano, T; Futakuchi, M; Fukamachi, K

Single Author

Effect of anatase type nanosized titanium dioxide particles on the rat lung and cultured macrophage, CANCER RESEARCH, 73(8) , 2013.04

Numano, T; Xu, JG; Futakuchi, M; Fukamachi, K; Furukawa, F; Suzui, M; Tsuda, H

Single Author

A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination, GENESIS, 51(4) 268-274, 2013.04

Fukamachi, K; Tanaka, H; Sakai, Y; Alexander, DB; Futakuchi, M; Tsuda, H; Suzui, M

Single Author

Inflammatory Activation after Experimental Cardiac Tamponade, EUROPEAN SURGICAL RESEARCH, 51(1-2) 1-13, 2013

Vass, A; Süveges, G; Érces, D; Nógrády, M; Varga, G; Földesi, I; Futakuchi, M; Imai, M; Okada, N; Okada, H; Boros, M; Kaszaki, J

Single Author

Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats, CANCER SCIENCE, 103(12) 2045-2050, 2012.12

Xu, JG; Futakuchi, M; Shimizu, H; Alexander, DB; Yanagihara, K; Fukamachi, K; Suzui, M; Kanno, J; Hirose, A; Ogata, A; Sakamoto, Y; Nakae, D; Omori, T; Tsuda, H

Single Author

Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice, CANCER SCIENCE, 103(8) 1440-1444, 2012.08

Takagi, A; Hirose, A; Futakuchi, M; Tsuda, H; Kanno, J

Single Author

Lack of promoting effect of titanium dioxide particles on chemically-induced skin carcinogenesis in rats and mice, JOURNAL OF TOXICOLOGICAL SCIENCES, 37(2) 317-327, 2012.04

Sagawa, Y; Futakuchi, M; Xu, JG; Fukamachi, K; Sakai, Y; Ikarashi, Y; Nishimura, T; Suzui, M; Tsuda, H; Morita, A

Single Author

A Cross-Species Analysis of a Mouse Model of Breast Cancer-Specific Osteolysis and Human Bone Metastases Using Gene Expression Profiling, BMC CANCER, 11 , 2011.07

Sadanandam, A; Futakuchi, M; Lyssiotis, CA; Gibb, WJ; Singh, RK

Single Author

Lack of promoting effect of titanium dioxide particles on ultraviolet B-initiated skin carcinogenesis in rats, FOOD AND CHEMICAL TOXICOLOGY, 49(6) 1298-1302, 2011.06

Xu, JG; Sagawa, Y; Futakuchi, M; Fukamachi, K; Alexander, DB; Furukawa, F; Ikarashi, Y; Uchino, T; Nishimura, T; Morita, A; Suzui, M; Tsuda, H

Single Author

Soluble receptor activator of nuclear factor-kB ligand and proteases: the involvement in osteolysis and its significance as therapeutics for bone metastasis of breast or prostate cancer, CLINICAL & EXPERIMENTAL METASTASIS, 28(2) 207, 2011.02

Futakuchi, M; Nannuru, KC; Wilson, TJ; Fukamachi, K; Suzui, M; Singh, RK

Single Author

Cancer prevention by bovine lactoferrin: from animal studies to human trial, BIOMETALS, 23(3) 399-409, 2010.06

Tsuda, H; Kozu, T; Iinuma, G; Ohashi, Y; Saito, Y; Saito, D; Akasu, T; Alexander, DB; Futakuchi, M; Fukamachi, K; Xu, JG; Kakizoe, T; Iigo, M

Single Author

Matrix Metalloproteinase (MMP)-13 Regulates Mammary Tumor-Induced Osteolysis by Activating MMP9 and Transforming Growth Factor-β Signaling at the Tumor-Bone Interface, CANCER RESEARCH, 70(9) 3494-3504, 2010.05

Nannuru, KC; Futakuchi, M; Varney, ML; Vincent, TM; Marcusson, EG; Singh, RK

Single Author

Involvement of macrophage inflammatory protein 1α (MIP1α) in promotion of rat lung and mammary carcinogenic activity of nanoscale titanium dioxide particles administered by intra-pulmonary spraying, CARCINOGENESIS, 31(5) 927-935, 2010.05

Xu, JG; Futakuchi, M; Iigo, M; Fukamachi, K; Alexander, DB; Shimizu, H; Sakai, Y; Tamano, S; Furukawa, F; Uchino, T; Tokunaga, H; Nishimura, T; Hirose, A; Kanno, J; Tsuda, H

Single Author

Cathepsin G-mediated enhanced TGF-β signaling promotes angiogenesis via upregulation of VEGF and MCP-1, CANCER LETTERS, 288(2) 162-169, 2010.02

Wilson, TJ; Nannuru, KC; Futakuchi, M; Singh, RK

Single Author

Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats, CANCER SCIENCE, 101(2) 341-346, 2010.02

Tanaka, H; Fukamachi, K; Futakuchi, M; Alexander, DB; Long, N; Tamamushi, S; Minami, K; Seino, S; Ohara, H; Joh, T; Tsuda, H

Single Author

A Medium-Term, Rapid Rat Bioassay Model for the Detection of Carcinogenic Potential of Chemicals, TOXICOLOGIC PATHOLOGY, 38(1) 182-187, 2010

Tsuda, H; Futakuchi, M; Fukamachi, K; Shirai, T; Imaida, K; Fukushima, S; Tatematsu, M; Furukawa, F; Tamano, S; Ito, N

Single Author

Enhanced expression and shedding of receptor activator of NF-κB ligand during tumor-bone interaction potentiates mammary tumor-induced osteolysis, CLINICAL & EXPERIMENTAL METASTASIS, 26(7) 797-808, 2009.10

Nannuru, KC; Futakuchi, M; Sadanandam, A; Wilson, TJ; Varney, ML; Myers, KJ; Li, XD; Marcusson, EG; Singh, RK

Single Author

Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine, BIOCHIMIE, 91(1) 86-101, 2009.01

Iigo, M; Alexander, DB; Long, N; Xu, JG; Fukamachi, K; Futakuchi, M; Takase, M; Tsuda, H

Single Author

Transforming growth factor-β signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation, CANCER SCIENCE, 100(1) 71-81, 2009.01

Futakuchi, M; Nannuru, KC; Varney, ML; Sadanandam, A; Nakao, K; Asai, K; Shirai, T; Sato, S; Singh, RK

Single Author

Construction of a Multi-Functional Helper-Dependent Adenovirus Based System for Cancer Gene Therapy, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 10(5) 939-960, 2009

Long, N; Hardiville, S; Pierce, A; Fukamachi, K; Futakuchi, M; Alexander, DB; Shirai, T; Tsuda, H

Single Author

Toxicology of Engineered Nanomaterials - A review of Carcinogenic Potential, ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 10(6) 975-980, 2009

Tsuda, H; Xu, JG; Sakai, Y; Futakuchi, M; Fukamachi, K

Single Author

Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-<i>f</i>]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model, FOOD AND CHEMICAL TOXICOLOGY, 46(8) 2758-2763, 2008.08

Kawabe, M; Futakuchi, M; Tamano, S; Shirai, T; Hirose, M

Single Author

Cathepsin g enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-κB ligand, CANCER RESEARCH, 68(14) 5803-5811, 2008.07

Wilson, TJ; Nannuru, KC; Futakuchi, M; Sadanandam, A; Singh, RK

Single Author

Effect of heat therapy using magnetic nanoparticles conjugated with cationic liposomes on prostate tumor in bone, PROSTATE, 68(7) 784-792, 2008.05

Kawai, N; Futakuchi, M; Yoshida, T; Ito, A; Sato, S; Naiki, T; Honda, H; Shirai, T; Kohri, K

Single Author

Heat therapy with cationic liposome might suppress the proliferation of prostate cancer in bone microenvironment via the reduction of TGF-β level in bone microenvironment, JOURNAL OF UROLOGY, 179(4) 420-421, 2008.04

Kawai, N; Futakuchi, M; Naiki, T; Hashimoto, Y; Tozawa, K; Kohri, K

Single Author

Transforming growth factor β derived from bone matrix promotes cell proliferation of prostate cancer and osteoclast activation-associated osteolysis in the bone microenvironment, CANCER SCIENCE, 99(2) 316-323, 2008.02

Sato, S; Futakuchi, M; Ogawa, K; Asamoto, M; Nakao, K; Asai, K; Shirai, T

Single Author

Differences in Expression Patterns of Cell Cycle Regulators after Cessation of Genotoxic and Non-genotoxic Carcinogen Treatment in the Rat Forestomach, JOURNAL OF TOXICOLOGIC PATHOLOGY, 21(2) 77-87, 2008

Mizoguchi, Y; Ogawa, K; Futakuchi, M; Takahashi, S; Hirose, M; Shirai, T

Single Author

Both early and late stages of hepatocarcinogenesis are enhanced in cx32 dominant negative mutant transgenic rats with disrupted gap junctional intercellular communication, JOURNAL OF MEMBRANE BIOLOGY, 218(1-3) 101-106, 2007.08

Hokaiwado, N; Asamoto, M; Futakuchi, M; Ogawa, K; Takahashi, S; Shirai, T

Single Author

Suppression of the prostate tumor growth and bone destruction in the bone microenvironment by heat therapy with magnetic nano-particle conjugated with cationic liposome, JOURNAL OF UROLOGY, 177(4) 182, 2007.04

Kawai, N; Yoshida, T; Ito, A; Futakuchi, M; Honda, H; Tozawa, K; Kohri, K

Single Author

Spleen but not tumor infiltration by dendritic and T cells is increased by intravenous adenovirus-Flt3 ligand injection, CANCER GENE THERAPY, 14(4) 364-371, 2007.04

Solheim, JC; Reber, AJ; Ashour, AE; Robinson, S; Futakuchi, M; Kurz, SG; Hood, K; Fields, RR; Shafer, LR; Cornell, D; Sutjipto, S; Zurawski, S; LaFace, DM; Singh, RK; Talmadge, JE

Single Author

MMP13 promotes prostate tumor growth in the bone microenvironment by activating TGF-β, CLINICAL & EXPERIMENTAL METASTASIS, 24(4) 281, 2007

Futakuchi, M; Sato, SY; Shirai, T

Single Author

TGF-β promotes prostate tumor growth in the bone microenvironment, CLINICAL & EXPERIMENTAL METASTASIS, 24(4) 282-283, 2007

Sato, SY; Futakuchi, M; Shirai, T

Single Author

Complete regression of experimental prostate cancer in nude mice by repeated hyperthermia using magnetite cationic liposomes and a newly developed solenoid containing a ferrite core, PROSTATE, 66(7) 718-727, 2006.05

Kawai, N; Ito, A; Nakahara, Y; Honda, H; Kobayashi, T; Futakuchi, M; Shirai, T; Tozawa, K; Kohri, K

Single Author

TGF-β directly and indirectly promote mammary tumor growth in the bone microenvironment by increasing osteoclastgenesis, CANCER RESEARCH, 66(8) , 2006.04

Futakuchi, M; Varney, ML; Sadanandam, A; Nakao, K; Asai, K; Shirai, T; Singh, RK

Single Author

Gene expression profiling using a unique murine mammary tumor model reveal role of novel genes regulating tumor-stromal interaction in mammary tumor-induced osteolysis, FASEB JOURNAL, 20(4) A222, 2006.03

Sadanandam, A; Futakuchi, M; Varney, M; Qiu, F; Singh, R

Single Author

Lack of prophylactic effect of incadronate an skeletal lesions associated with implants of prostate cancer, EUROPEAN UROLOGY, 49(1) 176-182, 2006.01

Hikosaka, A; Futakuchi, M; Ogiso, T; Suzuki, S; Kohri, K; Shirai, T

Single Author

Anticancer effect of hyperthermia on prostate cancer mediated by magnetite cationic liposomes and immune-response induction in transplanted syngeneic rats, PROSTATE, 64(4) 373-381, 2005.09

Kawai, N; Ito, A; Nakahara, Y; Futakuchi, M; Shirai, T; Honda, H; Kobayashi, T; Kohri, K

Single Author

Modification of an <i>in vivo</i> lung metastasis model of hepatocellular carcinoma by low dose n-nitrosomorpholine and diethylnitrosamine, CLINICAL & EXPERIMENTAL METASTASIS, 22(5) 441-447, 2005.09

Yoshino, H; Futakuchi, M; Cho, YM; Ogawa, K; Takeshita, F; Imai, N; Tamano, S; Shirai, T

Single Author

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL, CANCER CELL, 7(5) 485-496, 2005.05

Lynch, CC; Hikosaka, A; Acuff, HB; Martin, MD; Kawai, N; Singh, RK; Vargo-Gogola, TC; Begtrup, JL; Peterson, TE; Fingleton, B; Shirai, T; Matrisian, LM; Futakuchi, M

Single Author

Kinetics of marked development of lung metastasis of rat prostatic carcinomas transplanted in syngeneic rats, CLINICAL & EXPERIMENTAL METASTASIS, 22(4) 309-318, 2005

Zhao, LY; Futakuchi, M; Suzuki, S; Ohhara, Y; Hashimoto, T; Suzuki, T; Manabe, T; Shirai, T

Single Author

Suppression of metastasis by nuclear factor κB inhibitors in an <i>in vivo</i> lung metastasis model of chemically induced hepatocellular carcinoma, CANCER SCIENCE, 95(1) 18-24, 2004.01

Futakuchi, M; Ogawa, K; Tamano, S; Takahashi, S; Shirai, T

Single Author

Dose response study of conjugated fatty acid derived from safflower oil on mammary and colon carcinogenesis pretreated with 7,12-dimethylbenz[<i>a</i>]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH) in female Sprague-Dawley rats, CANCER LETTERS, 196(2) 161-168, 2003.07

Cheng, JL; Futakuchi, M; Ogawa, K; Iwata, T; Kasai, M; Tokudome, S; Hirose, M; Shirai, T

Single Author

Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses, CANCER LETTERS, 188(1-2) 163-170, 2002.12

Hirose, M; Yamaguchi, T; Mizoguchi, Y; Akagi, K; Futakuchi, M; Shirai, T

Single Author

Effects of antioxidant 1-<i>O</i>-hexyl-2,3,5-trimethylhydroquinone or ascorbic acid on carcinogenesis induced by administration of aminopyrine and sodium nitrite in a rat multi-organ carcinogenesis model, JAPANESE JOURNAL OF CANCER RESEARCH, 93(12) 1299-1307, 2002.12

Yada, H; Hirose, M; Tamano, S; Kawabe, M; Sano, M; Takahashi, S; Futakuchi, M; Miki, T; Shirai, T

Single Author

Suppression of lung metastasis by aspirin but not indomethacin in an <i>in vivo</i> model of chemically induced hepatocellular carcinoma, JAPANESE JOURNAL OF CANCER RESEARCH, 93(10) 1175-1181, 2002.10

Futakuchi, M; Ogawa, K; Sano, M; Tamano, S; Takeshita, F; Shirai, T

Single Author

Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine on carcinogenicity in the prostate, colon and pancreas, MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 506 129-136, 2002.09

Shirai, T; Kato, K; Futakuchi, M; Takahashi, S; Suzuki, S; Imaida, K; Asamoto, M

Single Author

Distinctive gene expression of receptor-type tyrosine kinase families during rat hepatocarcinogenesis, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 9(5) 473-480, 2002.05

Kuroda, H; Ohtsuru, A; Futakuchi, M; Kawashita, Y; Nagayama, Y; Fukuda, E; Namba, H; Shirai, T; Kanematsu, T; Yamashita, S

Single Author

Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP), CANCER LETTERS, 178(2) 131-139, 2002.04

Futakuchi, M; Cheng, JL; Hirose, M; Kimoto, N; Cho, YM; Iwata, T; Kasai, M; Tokudome, S; Shirai, T

Single Author

Chemoprevention of 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine-induced colon carcinogenesis by 1-<i>O</i>-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats, CARCINOGENESIS, 23(2) 283-287, 2002.02

Futakuchi, M; Hirose, M; Imaida, K; Takahashi, S; Ogawa, K; Asamoto, M; Miki, T; Shirai, T

Single Author

Organ dependent enhancement of rat 3,2′-dimethyl-4-aminobiphenyl (DMAB) carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP): positive effects on the intestine but not the prostate, CARCINOGENESIS, 22(8) 1295-1299, 2001.08

Imaida, K; Sano, M; Tamano, S; Asamoto, M; Ogawa, K; Futakuchi, M; Shirai, T

Single Author

Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats, CANCER LETTERS, 168(1) 15-21, 2001.07

Kimoto, N; Hirose, M; Futakuchi, M; Iwata, T; Kasai, M; Shirai, T

Single Author

Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice, INTERNATIONAL JOURNAL OF CANCER, 91(6) 797-802, 2001.03

Ogawa, K; Nakanishi, H; Takeshita, F; Futakuchi, M; Asamoto, M; Imaida, K; Tatematsu, M; Shirai, T

Single Author

Strategy for ABO-incompatible living-related liver transplantation, TRANSPLANTATION PROCEEDINGS, 32(7) 2104-2106, 2000.11

Hashimoto, T; Kondo, S; Suzuki, T; Nakamura, T; Shimizu, Y; Nakamura, Y; Hayashi, S; Zhao, L; Manabe, T; Futakuchi, M; Shirai, T

Single Author

Enhancing effects of Thai edible plants on 2-amino-3,8-dimethylimidazo(4,5-<i>f</i>)quinoxaline-hepatocarcinogenesis in a rat medium-term bioassay, CANCER LETTERS, 158(2) 195-201, 2000.10

Tiwawech, D; Hirose, M; Futakuchi, M; Lin, C; Thamavit, W; Ito, N; Shirai, T

Single Author

Suppressive effects of dietary genistin and daidzin on rat prostate carcinogenesis, JAPANESE JOURNAL OF CANCER RESEARCH, 91(8) 786-791, 2000.08

Kato, K; Takahashi, S; Cui, L; Toda, T; Suzuki, S; Futakuchi, M; Sugiura, S; Shirai, T

Single Author

Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats, CANCER LETTERS, 155(1) 79-88, 2000.07

Hirose, M; Yamaguchi, T; Lin, C; Kimoto, N; Futakuchi, M; Kono, T; Nishibe, S; Shirai, T

Single Author

Inhibitory effects of low doses of melatonin on induction of preneoplastic liver lesions in a medium-term liver bioassay in F344 rats: relation to the influence of electromagnetic near field exposure, CANCER LETTERS, 155(1) 105-114, 2000.07

Imaida, K; Hagiwara, A; Yoshino, H; Tamano, S; Sano, M; Futakuchi, M; Ogawa, K; Asamoto, M; Shirai, T

Single Author

Protective mechanisms against the intestinal nematode Strongyloides venezuelensis in Schistosoma japonicum-infected mice, PARASITE IMMUNOLOGY, 22(6) 279-286, 2000.06

Maruyama, H; Osada, Y; Yoshida, A; Futakuchi, M; Kawaguchi, H; Zhang, RL; Fu, J; Shirai, T; Kojima, S; Ohta, N

Single Author

Experimental prostate carcinogenesis - rodent models, MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 462(2-3) 219-226, 2000.04

Shirai, T; Takahashi, S; Cui, L; Futakuchi, M; Kato, K; Tamano, S; Imaida, K

Single Author

Establishment of an <i>in vivo</i> highly metastatic rat hepatocellular carcinoma model, JAPANESE JOURNAL OF CANCER RESEARCH, 90(11) 1196-1202, 1999.11

Futakuchi, M; Hirose, M; Ogiso, T; Kato, K; Sano, M; Ogawa, K; Shirai, T

Single Author

Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-<i>b</i>]pyridine (PhIP) in the rat prostate and induction of invasive carcinomas by subsequent treatment with testosterone propionate, CANCER LETTERS, 143(2) 217-221, 1999.09

Shirai, T; Cui, L; Takahashi, S; Futakuchi, M; Asamoto, M; Kato, K; Ito, N

Single Author

Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats, CANCER LETTERS, 143(2) 173-178, 1999.09

Hirose, M; Takahashi, S; Ogawa, K; Futakuchi, M; Shirai, T; Shibutani, M; Uneyama, C; Toyoda, K; Iwata, H

Single Author

Phenolics: Blocking agents for heterocyclic amine-induced carcinogenesis, FOOD AND CHEMICAL TOXICOLOGY, 37(9-10) 985-992, 1999.09

Hirose, M; Takahashi, S; Ogawa, K; Futakuchi, M; Shirai, T

Single Author

Development of androgen-independent carcinomas from androgen-dependent preneoplastic lesions in the male accessory sex organs of rats treated with 3,2′-dimethyl-4-aminobiphenyl and testosterone propionate, JAPANESE JOURNAL OF CANCER RESEARCH, 90(1) 23-30, 1999.01

Iwasaki, S; Kato, K; Mori, T; Takahashi, S; Futakuchi, M; Shirai, T

Single Author

ABO-incompatible living related liver transplantation for fulminant hepatitis: Report of a successful pediatric case with long-term follow-up, TRANSPLANTATION PROCEEDINGS, 30(7) 3510-3512, 1998.11

Hashimoto, T; Suzuki, T; Shimizu, Y; Otobe, Y; Nakamura, T; Nakamura, Y; Tanaka, M; Ito, K; Ueda, N; Hayashi, S; Manabe, T; Futakuchi, M; Shirai, T

Single Author

Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats, INTERNATIONAL JOURNAL OF CANCER, 77(5) 773-777, 1998.08

Hirose, M; Yamaguchi, T; Kimoto, N; Ogawa, K; Futakuchi, M; Sano, M; Shirai, T

Single Author

Stage and organ dependent effects of 1-<i>O</i>-hexyl-2,3,5-trimethylhydroquinone, ascorbic acid derivatives, n-heptadecane-8,10-dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model, INTERNATIONAL JOURNAL OF CANCER, 76(6) 851-856, 1998.06

Ogawa, K; Futakuchi, M; Hirose, M; Boonyaphiphat, P; Mizoguchi, Y; Miki, T; Shirai, T

Single Author

Inhibition of DMBA-initiated rat mammary tumour development by 1-0-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives, EUROPEAN JOURNAL OF CANCER PREVENTION, 7(2) 153-159, 1998.04

Futakuchi, M; Hirose, M; Miki, T; Tanaka, H; Ozaki, M; Shirai, T

Single Author

Studies of initiation and promotion of carcinogenesis by <i>N</i>-nitroso compounds, CANCER LETTERS, 123(2) 185-191, 1998.01

Hasegawa, R; Futakuchi, M; Mizoguchi, Y; Yamaguchi, T; Shirai, T; Ito, N; Lijinsky, W

Single Author

Prevention by antioxidants of heterocyclic amine-induced carcinogenesis in a rat medium-term liver bioassay: results of extended and combination treatment experiments, EUROPEAN JOURNAL OF CANCER PREVENTION, 7(1) 61-67, 1998

Hirose, M; Futakuchi, M; Tanaka, H; Orita, SI; Ito, T; Miki, T; Shirai, T

Single Author

Clinicopathological analysis on cancers of autopsy cases in a geriatric hospital, PATHOLOGY INTERNATIONAL, 47(5) 293-300, 1997.05

Imaida, K; Hasegawa, R; Kato, T; Futakuchi, M; Takahashi, S; Ogawa, K; Asamoto, M; Yamamoto, T; Suzuki, K; Inagaki, T; Shinagawa, N; Shirai, T

Single Author

Effects of synthetic and naturally occurring compounds on heterocyclic (HCA) amine-induced hepatocarcinogenesis in the rat., ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 213 173-AGFD, 1997.04

Hirose, M; Futakuchi, M; Tanaka, H; Ito, T; Tiwawech, D; Shirai, T

Single Author

The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods, CANCER RESEARCH, 57(2) 195-198, 1997.01

Shirai, T; Sano, M; Tamano, S; Takahashi, S; Hirose, M; Futakuchi, M; Hasegawa, R; Imaida, K; Matsumoto, K; Wakabayashi, K; Sugimura, T; Ito, N

Single Author

Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes, CANCER LETTERS, 112(1) 33-45, 1997.01

Masui, T; Nakanishi, H; Inada, K; Imai, T; Mizoguchi, Y; Yada, H; Futakuchi, M; Shirai, T; Tatematsu, M

Single Author

Modification of the carcinogenic potency of quinoline, a hepatocarcinogen, by fluorine atom substitution: Evaluation of carcinogenicity by a medium-term assay, BIOLOGICAL & PHARMACEUTICAL BULLETIN, 20(1) 40-43, 1997.01

Saeki, K; Kadoi, M; Kawazoe, Y; Futakuchi, M; Tiwawech, D; Shirai, T

Single Author

Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat, CANCER LETTERS, 106(2) 263-269, 1996.09

Futakuchi, M; Lijinsky, W; Hasegawa, R; Hirose, M; Ito, N; Shirai, T

Single Author

Low susceptibility of the spontaneously hypertensive rat (SHR) to quinoline-induction of hepatic hemangioendothelial sarcomas, CANCER LETTERS, 104(1) 37-41, 1996.06

Futakuchi, M; Hasegawa, R; Yamamoto, A; Cui, L; Ogiso, T; Ito, N; Shirai, T

Single Author

A study on the retrogradation of waxy corn starch, NIPPON KAGAKU KAISHI, (5) 477-482, 1996.05

Yamazaki, I; Futakuchi, M; Ono, S; Yoshimura, T; Morita, H; Tsukurimichi, E; Takai, J; Shimasaki, C

Single Author

VOID FRACTION DISTRIBUTION IN A BOILING WATER-REACTOR FUEL ASSEMBLY AND THE EVALUATION OF SUBCHANNEL ANALYSIS CODES, NUCLEAR TECHNOLOGY, 112(3) 388-400, 1995.12

INOUE, A; FUTAKUCHI, M; YAGI, M; MITSUTAKE, T; MOROOKA, SI

Single Author

INCREASED RISK OF MAMMARY-CARCINOMA DEVELOPMENT FOLLOWING TRANSPLACENTAL AND TRANS-BREAST MILK EXPOSURE TO A FOOD-DERIVED CARCINOGEN, 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP), IN SPRAGUE-DAWLEY RATS, CANCER RESEARCH, 55(19) 4333-4338, 1995.10

HASEGAWA, R; KIMURA, J; YAONO, M; TAKAHASHI, S; KATO, T; FUTAKUCHI, M; FUKUTAKE, M; FUKUTOME, K; WAKABAYASHI, K; SUGIMURA, T; ITO, N; SHIRAI, T

Single Author

HEPATOCYTE GROWTH-FACTOR ENHANCEMENT OF PRENEOPLASTIC HEPATIC FOCI DEVELOPMENT IN RATS TREATED WITH DIETHYLNITROSAMINE AND N-ETHYL-N-HYDROXYETHYLNITROSAMINE, JAPANESE JOURNAL OF CANCER RESEARCH, 86(8) 718-723, 1995.08

YAONO, M; HASEGAWA, R; MIZOGUCHI, Y; FUTAKUCHI, M; NAKAMURA, T; ITO, N; SHIRAI, T

Single Author

SITE-SPECIFIC EFFECTS OF TESTOSTERONE PROPIONATE ON THE PROSTATE OF RAT PRETREATED WITH 3,2'-DIMETHYL-4-AMINOBIPHENYL - DOSE-DEPENDENT INDUCTION OF INVASIVE CARCINOMAS, JAPANESE JOURNAL OF CANCER RESEARCH, 86(7) 645-648, 1995.07

SHIRAI, T; TAMANO, S; SANO, M; IMAIDA, K; HAGIWARA, A; FUTAKUCHI, M; TAKAHASHI, S; HIROSE, M

Single Author

KI-RAS MUTATIONS WITH FREQUENT NORMAL ALLELE LOSS VERSUS ABSENCE OF P53 MUTATIONS IN RAT PROSTATE AND SEMINAL-VESICLE CARCINOMAS INDUCED WITH 3,2'-DIMETHYL-4-AMINOBIPHENYL, MOLECULAR CARCINOGENESIS, 13(1) 21-26, 1995.05

MASUI, T; SHIRAI, T; IMAIDA, K; HIROSE, M; FUTAKUCHI, M; TATEMATSU, M; ITO, N

Single Author

MISORIENTATION DEPENDENCE OF NANOMETER GRAIN-BOUNDARY SLIDING OF [011]-TWIST BOUNDARIES IN COPPER, SCRIPTA METALLURGICA ET MATERIALIA, 32(8) 1277-1282, 1995.04

MONZEN, R; FUTAKUCHI, M; SUZUKI, T

Single Author

VOID FRACTION CORRELATION FOR ROD BUNDLE VOID FRACTION CORRELATION-BASED ON VOID DATA OF BWR FUEL ASSEMBLY MEASURED BY X-RAY CT SCANNER, JOURNAL OF THE ATOMIC ENERGY SOCIETY OF JAPAN, 37(2) 133-143, 1995.02

ISHIZUKA, T; INOUE, A; KUROSU, T; AOKI, T; FUTAKUCHI, M; YAGI, M; MOROOKA, S; HOSHIDE, A; YOSHIMURA, K

Single Author

PHENOTYPIC ALTERATION OF HEPATOCELLULAR FOCI IN RATS TREATED WITH CLOFIBRATE AND PHENOBARBITAL, CANCER LETTERS, 83(1-2) 89-95, 1994.08

HASEGAWA, R; YOSHIDA, T; MIZOGUCHI, Y; FUTAKUCHI, M; KIM, DJ; CUI, L; ITO, N

Single Author

INHIBITION OF MAMMARY-GLAND CARCINOGENESIS BY GREEN TEA CATECHINS AND OTHER NATURALLY-OCCURRING ANTIOXIDANTS IN FEMALE SPRAGUE-DAWLEY RATS PRETREATED WITH 7,12-DIMETHYLBENZ[A]ANTHRACENE, CANCER LETTERS, 83(1-2) 149-156, 1994.08

HIROSE, M; HOSHIYA, T; AKAGI, K; FUTAKUCHI, M; ITO, N

Single Author

13-WEEK ORAL TOXICITY STUDY OF MAGNESIUM-CHLORIDE IN B6C3F(1) MICE, TOXICOLOGY LETTERS, 73(1) 25-32, 1994.07

TANAKA, H; HAGIWARA, A; KURATA, Y; OGISO, T; FUTAKUCHI, M; ITO, N

Single Author

SYNERGISTIC ENHANCEMENT OF HEPATIC FOCI DEVELOPMENT BY COMBINED TREATMENT OF RATS WITH 10 HETEROCYCLIC AMINES AT LOW-DOSES, CARCINOGENESIS, 15(5) 1037-1041, 1994.05

HASEGAWA, R; MIYATA, E; FUTAKUCHI, M; HAGIWARA, A; NAGAO, M; SUGIMURA, T; ITO, N

Single Author

COMPARISON OF REVERSIBILITY OF RAT FORESTOMACH LESIONS INDUCED BY GENOTOXIC AND NONGENOTOXIC CARCINOGENS, JAPANESE JOURNAL OF CANCER RESEARCH, 84(11) 1120-1129, 1993.11

KAGAWA, M; HAKOI, K; YAMAMOTO, A; FUTAKUCHI, M; HIROSE, M

Single Author

EFFECT OF AN ELEMENT ADDITION ON RELAXATION OF ELASTIC DISTORTION BASED ON PARTICLE-BLOCKED GRAIN-BOUNDARY SLIDING, SCRIPTA METALLURGICA ET MATERIALIA, 29(4) 563-566, 1993.08

MONZEN, R; FUTAKUCHI, M; MIURA, H

Single Author

MEASUREMENT OF GRAIN-BOUNDARY SLIDING OF [011] TWIST BOUNDARIES IN COPPER BY ELECTRON-MICROSCOPY, ACTA METALLURGICA ET MATERIALIA, 41(6) 1643-1646, 1993.06

MONZEN, R; FUTAKUCHI, M; KITAGAWA, K; MORI, T

Single Author

EFFECTS OF SODIUM-NITRITE AND CATECHOL, 3-METHOXYCATECHOL, OR BUTYLATED HYDROXYANISOLE IN COMBINATION IN A RAT MULTIORGAN CARCINOGENESIS MODEL, CANCER RESEARCH, 53(1) 32-37, 1993.01

HIROSE, M; TANAKA, H; TAKAHASHI, S; FUTAKUCHI, M; FUKUSHIMA, S; ITO, N

Single Author

MODIFICATION OF HEPATOCARCINOGENESIS AND RENAL CARCINOGENESIS BY CATECHOL AND ITS ISOMERS IN RATS PRETREATED WITH N-ETHYL-N-HYDROXYETHYLNITROSAMINE, TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 13(3) 127-137, 1993

OKAZAKI, S; HOSHIYA, T; TAKAHASHI, S; FUTAKUCHI, M; SAITO, K; HIROSE, M

Single Author

HIGH-RESOLUTION MEASUREMENTS OF ANALOG STATES IN MN-51, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 52(3) 802-810, 1983

ARAI, E; FUTAKUCHI, M; KOMAKI, J; OGAWA, M; OGURI, Y

Single Author

HIGH-RESOLUTION MEASUREMENTS OF ANALOG STATES IN CO-57, NUCLEAR PHYSICS A, 378(2) 259-272, 1982

ARAI, E; FUTAKUCHI, M; KAMADA, H; KOMAKI, J; MATSUZAKI, T; OGAWA, M; OGURI, Y

Single Author

大腸がん肝転移巣を拡大させるマクロファージの同定と腫瘍細胞増殖シグナル解析(Identification of macrophages that expand liver metastases of colorectal cancer), 日本病理学会会誌, 113(1) 311, 2024.02

大江 倫太郎, 内山 尚哉, 北岡 匠, 鈴木 一司, 樺澤 崇允, 二口 充

口腔扁平上皮癌の骨浸潤に関与する腫瘍間質相互作用(Tumor stromal interaction involved in bone invasion of oral squamous cell carcinoma), 日本病理学会会誌, 113(1) 285, 2024.02

内山 尚哉, 笹原 庸由, 北岡 匠, 樺澤 崇允, 大江 倫太郎, 二口 充

Luminal乳がん骨転移におけるc-jun機能解析と治療戦略, 日本がん転移学会学術集会・総会プログラム抄録集, 33rd , 2024

中山淳, 中山淳, 韓宇軒, 二口充, 仙波憲太郎

トリプルネガティブ乳癌におけるCD8陽性T細胞によるPD-L1陽性MΦの誘導の組織学的空間解析(Histological spatial analysis on the induction of PD-L1+macrophages by CD8+ T cells of triple-negative breast cancer), 日本癌学会総会記事, 82回 1589, 2023.09

北岡 匠, 鈴木 一司, 樺澤 崇允, 大江 倫太郎, 二口 充

腫瘍関連マクロファージの浸潤は肺腺癌のリンパ節における増殖に関与するが原発巣での増殖には関与しない(Involvement of TAMs on tumor growth in the lymph node microenvironment but not in primary site), 日本癌学会総会記事, 82回 846, 2023.09

樺澤 崇允, 大江 倫太郎, 鈴木 一司, 北岡 匠, 二口 充

脊髄神経膠腫の臨床像についての検討, 日本脳腫瘍学会学術集会プログラム・抄録集, 41st , 2023

中村和貴, 松田憲一朗, 大江倫太郎, 二口充, 金村米博, 園田順彦

Grant-in-Aid for Scientific Research(C)，2022.04 - 2025.03

Grant-in-Aid for Scientific Research(C)，2022.04 - 2025.03