Hemoglobin β Expression Is Associated with Poor Prognosis in Clear Cell Renal Cell Carcinoma, BIOMEDICINES, 11(5) , 2023.04

Kurota, Y; Takeda, Y; Ichiyanagi, O; Saitoh, S; Ito, H; Naito, S; Asao, H; Tsuchiya, N

Single Author

Initial Myeloid Cell Status Is Associated with Clinical Outcomes of Renal Cell Carcinoma, BIOMEDICINES, 11(5) , 2023.04

Sabrina, S; Takeda, Y; Kato, T; Naito, S; Ito, H; Takai, Y; Ushijima, M; Narisawa, T; Kanno, H; Sakurai, T; Saitoh, S; Araki, A; Tsuchiya, N; Asao, H

Single Author

MDSCs function analysis as a prediction of therapeutic effect for patients with advanced renal cell carcinoma, CANCER SCIENCE, 114 1406, 2023.02

Sabrina, S; Kato, T; Takeda, Y; Naito, S; Ito, H; Takai, Y; Ushijima, M; Narisawa, T; Kanno, H; Sakurai, Y; Tsuchiya, N; Asao, H

Single Author

MDSCs function analysis as a prediction of therapeutic effect for patients with advanced renal cell carcinoma, CANCER SCIENCE, 114 1406, 2023.02

Sabrina, S., Kato, T., Takeda, Y., Naito, S., Ito, H., Takai, Y., Ushijima, M., Narisawa, T., Kanno, H., Sakurai, Y., Tsuchiya, N., Asao, H.

Single Author

細胞の挙動に関連する細胞シグナル伝達の5つのパターン(Five Patterns of Cell Signaling Associated with Cell Behavior), 山形医学, 40(1) 1-20, 2022.02

武田 裕司, 河野 和晴, 馬 鋭, 斉藤 真一, 浅尾 裕信

Single Author

Heterogeneity of neutrophils in renal cell and urothelial carcinoma patients during immune checkpoint inhibition therapy, CANCER SCIENCE, 113 514, 2022.02

Saima, S; Kato, T; Takeda, Y; Naito, S; Ito, H; Takai, Y; Ushijima, M; Ozawa, M; Narisawa, T; Kanno, H; Sakurai, T; Tsuchiya, N; Asao, H

Single Author

GPI-80 Augments NF-κB Activation in Tumor Cells, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(21) , 2021.11

Takeda, Y; Kurota, Y; Kato, T; Ito, H; Araki, A; Nara, H; Saitoh, S; Tanaka, N; Tsuchiya, N; Asao, H

Single Author

Physiological heating augments the anti-inflammatory reactions during granulocyte/monocyte apheresis: A in vitro study, Therapeutic Apheresis and Dialysis, 25(5) 671-680, 2021.10

Nishise Shoichi, Takeda Yuji, Abe Yasuhiko, Sasaki Yu, Saitoh Shinichi, Nara Hidetoshi, Asao Hironobu, Ueno Yoshiyuki

Single Author

Developmental retardation in neonates of aldehyde reductase (AKR1A)-deficient mice is associated with low ascorbic acid and high corticosterone levels., The Journal of nutritional biochemistry, 91 108604, 2021.02

Naoki Ishii, Takujiro Homma, Yuji Takeda, Naing Ye Aung, Ken-Ichi Yamada, Satoshi Miyata, Hironobu Asao, Mitsunori Yamakawa, Junichi Fujii

Single Author

Analysis of inflammatory response during intravesical immunotherapy with BCG for non-muscle invasive bladder cancer, CANCER SCIENCE, 112 841, 2021.02

Takeda, Y; Kato, T; Naito, S; Ito, H; Ushijima, M; Narisawa, T; Kanno, H; Kurota, Y; Tsuchiya, N; Asao, H

Single Author

Dynamic changes in myeloid cells in urological cancer patients during immune checkpoint treatment, CANCER SCIENCE, 112 837, 2021.02

Kato, T; Takeda, Y; Naito, S; Ito, H; Ushijima, M; Narisawa, T; Yagi, M; Kanno, H; Sakurai, T; Yamanobe, T; Asao, H; Tsuchiya, N

Single Author

Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue., Free radical biology & medicine, 162 255-265, 2021.01

Takujiro Homma, Yuji Takeda, Tomoyuki Nakano, Shinya Akatsuka, Daisuke Kinoshita, Toshihiro Kurahashi, Shinichi Saitoh, Ken-Ichi Yamada, Satoshi Miyata, Hironobu Asao, Kaoru Goto, Tetsu Watanabe, Masa...

Single Author

Physiological heating augments the anti-inflammatory reactions during granulocyte/monocyte apheresis: A in vitro study, THERAPEUTIC APHERESIS AND DIALYSIS, 25(5) 671-680, 2020.12

Shoichi Nishise, Yuji Takeda, Yasuhiko Abe, Yu Sasaki, Shinichi Saitoh, Hidetoshi Nara, Hironobu Asao, Yoshiyuki Ueno

Single Author

Analysis of intestinal immunity and flora in a collagen-induced mouse arthritis model: differences during arthritis progression., International immunology, 32(1) 49-56, 2020.01

Nobuhito Nemoto, Yuji Takeda, Hidetoshi Nara, Akemi Araki, Md Yeashin Gazi, Yuya Takakubo, Yasushi Naganuma, Michiaki Takagi, Hironobu Asao

Single Author

コラーゲン誘発関節炎マウスモデルにおける腸管免疫と腸内細菌叢解析　関節炎進行時の差(Analysis of intestinal immunity and flora in a collagen-induced mouse arthritis model: differences during arthritis progression), International Immunology, 32(1) 49-56, 2020.01

Nemoto Nobuhito, Takeda Yuji, Nara Hidetoshi, Araki Akemi, Gazi Md. Yeashin, Takakubo Yuya, Naganuma Yasushi, Takagi Michiaki, Asao Hironobu

Single Author

Heterozygous SOD1 deficiency in mice with an NZW background causes male infertility and an aberrant immune phenotype., Free radical research, 53(11-12) 1060-1072, 2019.12

Takujiro Homma, Yuji Takeda, Satoshi Sakahara, Naoki Ishii, Sho Kobayashi, Hiroyuki Abe, Hironobu Asao, Junichi Fujii

Single Author

GPI-80 as a Useful Index for Myeloid Cell Heterogeneity and a Potential Prognostic Biomarker for Metastatic Renal Cell Carcinoma., The Tohoku journal of experimental medicine, 249(3) 203-212, 2019.11

Tomoyuki Kato, Yuji Takeda, Hiromi Ito, Yuta Kurota, Atsushi Yamagishi, Toshihiko Sakurai, Sei Naito, Akemi Araki, Hidetoshi Nara, Hironobu Asao, Norihiko Tsuchiya

Single Author

Interleukin-12p40 variant form reduces Interleukin-12p80 secretion, CYTOKINE, 120 251-257, 2019.08

Oshikiri, Y; Nara, H; Takeda, Y; Araki, A; Nemoto, N; Gazi, MY; Saito, S; Saitoh, S; Nakajima, O; Asao, H

Single Author

IL-21 Enhances the Development of Colitis-Associated Colon Cancer: Possible Involvement of Activation-Induced Cytidine Deaminase Expression., Journal of immunology (Baltimore, Md. : 1950), 202(11) 3326-3333, 2019.04

Akemi Araki, Lianjin Jin, Hidetoshi Nara, Yuji Takeda, Nobuhito Nemoto, Md Yeashin Gazi, Hironobu Asao

Multiple Authorship (Only Japanese)

The prognostic value of glycosylphosphatidylinositol-anchored 80 kD protein (GPI-80) positive myeloid derived suppressor cells (MDSCs) in peripheral blood of metastatic renal cell carcinoma (mRCC) patients., JOURNAL OF CLINICAL ONCOLOGY, 37(7) , 2019.03

Kato, T; Takeda, Y; Kurota, Y; Naito, S; Ito, H; Araki, A; Asao, H; Tsuchiya, N

Single Author

Interleukin-12p40 variant form reduces Interleukin-12p80 secretion., Cytokine, 2019

Oshikiri Y, Nara H, Takeda Y, Araki A, Nemoto N, Gazi Md Yeashin, Saito S, Saitoh S, Nakajima O, Asao H.

Multiple Authorship (Only Japanese)

Interleukin-12p40 variant form reduces Interleukin-12p80 secretion., Cytokine, 2019

Oshikiri Y, Nara H, Takeda Y, Araki A, Nemoto N, Gazi Md Yeashin, Saito S, Saitoh S, Nakajima O, Asao H

Single Author

Augmentation of the expression of the eotaxin receptor on duodenal neutrophils by IL-21, Cytokine, 110 194-203, 2018.10

Yuji Takeda, Tomoyuki Kato, Nobuhito Nemoto, Akemi Araki, Mohammad Yeashin Gazi, Hidetoshi Nara, Hironobu Asao

Single Author

Systemic neutrophil migration and rapid consumption of neutrophils in the spleen., Data in brief, 20 680-682, 2018.10

Yuji Takeda, Tomoyuki Kato, Nobuhito Nemoto, Akemi Araki, Mohammad Yeashin Gazi, Hidetoshi Nara, Hironobu Asao

Single Author

IL-21 Attenuates FITC-Induced Contact Hypersensitivity Response via Regulation of Dendritic Cell Function, Journal of Investigative Dermatology, 138(10) 2174-2184, 2018.10

Hidetoshi Nara, Mikako Komatsu, Yuji Tekeda, Akemi Araki, Nasrin Akhter, Hironobu Asao

Single Author

Adsorption of Soluble Immunoglobulin-Type Adhesion Molecules to Cellulose Acetate Beads, Therapeutic Apheresis and Dialysis, 22(3) 261-265, 2018.06

Shoichi Nishise, Yuji Takeda, Hidetoshi Nara, Yasuhiko Abe, Yu Sasaki, Hironobu Asao, Yoshiyuki Ueno

Single Author

Protein tyrosine phosphatase SHP-2 is involved in the interleukin-21-induced activation of extracellular signal-regulated kinase 1/2, Tohoku Journal of Experimental Medicine, 244(3) 187-193, 2018.03

Lianjin Jin, Hidetoshi Nara, Mizanur Rahman, Yuji Takeda, Akemi Araki, Hironobu Asao

Multiple Authorship (Only Japanese)

Hyper-IgE syndrome, Journal of Japan Society of Immunology & Allergology in Otolaryngology, 36(4) 267-269, 2018

Furukawa Takatoshi, Takada Yuji, Asao Hironobu, Ohta Nobuo, Kakehata Seiji

Single Author

Effect of Temperature on Granulocyte and Monocyte Adsorption to Cellulose Acetate Beads., Ther Apher Dial, 2017

Nishise S,Takeda Y,Abe Y, Sasaki Y, Nara H, Asao H, Ueno Y.

Multiple Authorship (Including Foreigners)

Relationship between Immunological Abnormalities in Rat Models of Diabetes Mellitus and the Amplification Circuits for Diabetes., J Diabetes Res, 2017

Takeda Y, Shimomura T, Asao H, Wakabayashi I.

Multiple Authorship (Including Foreigners)

Analysis of signal transducers using flow cytometry is useful for detection of contractive and fluctuating signal., Yamagata Med J, 2017

Takeda Y, Nara H, Asao H

Multiple Authorship (Including Foreigners)

Selective induction of anti-inflammatory monocyte-platelet aggregates in a model of pulsatile blood flow at low shear rates., Platelets, 2016

Takeda Y, Marumo M, Nara H, Feng Z-G, Asao H, Wakabayashi I.

Multiple Authorship (Including Foreigners)

Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-Mediated T Helper Cell Type 1 Responses., J Biol Chem, 2016

Akhter N, Takeda Y, Nara H. Araki A, Ishii N, Asao N, Asao H.

Multiple Authorship (Including Foreigners)

The pattern of GPI-80 expression is a useful marker for unusual myeloid maturation in peripheral blood., Clin Exp Immunol., 2016

Takeda Y, Kato T, Ito H, Kurota Y, Yamagishi A, Sakurai T, Araki A, Nara H, Tsuchiya N, Asao H.

Multiple Authorship (Including Foreigners)

Circulating miR-223 in Oral Cancer: Its Potential as a Novel Diagnostic Biomarker and Therapeutic Target., PLoS One, 2016

Tachibana H, Sho R, Takeda Y, Zhang X, Yoshida Y, Narimatsu H, Otani K, Ishikawa S, Fukao A, Asao H, Iino M.

Multiple Authorship (Including Foreigners)

Human peripheral neutrophils express functional IL-21 receptors., Inflammation, 2014

Takeda Y, Nara H, Araki A and Asao H

Multiple Authorship (Including Foreigners)

Identification of Novel ALK Rearrangement A2M–ALK in a Neonate with Fetal Lung Interstitial Tumor., Genes Chromosomes Cancer, 2014

Onoda T, Kanno M, Sato H, Takahashi N, Izumino H, Ohta H, Emura T, Katoh H, Ohizumi H, Ohtake H, Asao H, Dehner LP, Hill AD, Hayasaka K, and Mitsui T

Multiple Authorship (Including Foreigners)

Role of Interleukin-21 isoform in dextran sulfate sodium (DSS)-induced colitis., Cytokine, 2013

Araki A, Nara H, Rahman M, Onoda T, Li J, Juliana FM, Jin L, Murata K, Takeda Y and Asao H

Multiple Authorship (Including Foreigners)

Apurinic/apyrimidinic endonuclease1/redox factor-1 (Ape1/Ref-1) is essential for IL-21-induced signal transduction through ERK1/2 pathway., Biochem. Biophys. Res. Commun., 420 628-634, 2012.04

Juliana FM, Nara H, Onoda T, Rahman M, Araki A, Jin L, Fujii H, Tanaka N, Hoshino T and Asao H

Multiple Authorship (Including Foreigners)

IL-21 isoform is a membrane-bound ligand and activates directly interacted cells., Cytokine, 2012

Nara H, Rahman M, Araki A, Jin L, Takeda Y and Asao H

Multiple Authorship (Including Foreigners)

Intrinsic Temperature Sensitivity of Influenza C Virus Hemagglutinin-Esterase-Fusion Protein., J. Virol., 2012

Takashita E, Muraki Y, Sugawara K, Asao H, Nishimura H, Suzuki K, Tsuji T, Hongo S, Ohara Y, Kawaoka Y, Ozawa M, Matsuzaki Y

Multiple Authorship (Only Japanese)

Impaired IL-7 signaling may explain a case of atypical JAK3-SCID., Cytokine, 49 221-228, 2010.02

Li J, Nara H, Rahman M, Juliana FM, Araki A and Asao H

Multiple Authorship (Including Foreigners)

Regulation of interleukin-21 receptor expression and its signal transduction by WSB-2., Biochem. Biophys. Res. Commun., 392 171-177, 2010.02

Nara H, Onoda T, Rahman M, Araki A, Juliana FM, Tanaka N, Asao H

Multiple Authorship (Including Foreigners)

Interactions between vitreous-derived cells and vascular endothelial cells in vitreoretinal diseases., Acta Ophthalmol., 2010

Tojo N, Kashiwagi Y, Nishitsuka K, Yamamoto S, Asao H, Sugawara N, Yamashita T, Yamamoto T, Yamashita H

Multiple Authorship (Only Japanese)

Transcriptional Activation of the Interleukin-21 Gene and Its Receptor Gene by Human T-cell Leukemia Virus Type 1 Tax in Human T-cells.（共著）, J. Biol. Chem., 284 25501-25511, 2009.09

Mizuguchi M, Asao H, Hara T, Higuchi M, Fijii M and Nakamura M

Multiple Authorship (Including Foreigners)

Cloning and Characterization of an Isoform of Interleukin-21.（共著）, FEBS Letters, 581 4001-4009, 2007.07

56. Rahman M, Nara H, Onoda T, Araki A, Li J. Hoshino T. and Asao H

Multiple Authorship (Including Foreigners)

Human CD4+ central and effector memory T cells produce IL-21; Effect on cytokine-driven proliferation of CD4+ T cell subsets.（共著）, Int. Immunol., 19 1191-1199, 2007.07

57. Onoda T, Rahman M, Nara H, Araki A, Makabe K, Tsumoto K, Kumagai I, Kudo T, Ishii N, Tanaka N, Sugamura K, Hayasaka K and Asao H

Multiple Authorship (Including Foreigners)

Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production. , Biochemical Journal, 402 219-227, 2007.03

Iuchi Y, Okada F, Onuma K, Onoda T, Asao H, Kobayashi M, Fujii J

Multiple Authorship (Including Foreigners)

The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinson's disease., J Neurosci., 2006

Arawaka S, Wada M, Goto S, Karube H, Sakamoto M, Ren CH, Koyama S, Nagasawa H, Kimura H, Kawanami T, Kurita K, Tajima K, Daimon M, Baba M, Kido T, Saino S, Goto K, Asao H, Kitanaka C, Takashita E, Hon...

Multiple Authorship (Including Foreigners)

Hrs, a mammalian master molecule in vesicular transport and protein-sorting, suppresses the degradation of ESCRT proteins STAM1 and STAM2., J. Biol. Chem., 2005

Kobayashi H, Tanaka N, Asao H, Miura S, Kyuuma M, Semura K, Ishii N, Sugamura K

Multiple Authorship (Only Japanese)

Enhanced expression of IL-18 and its receptor in idiopathic pulmonary fibrosis. , Am J Respir Cell Mol Biol., 2004

Kitasato Y, Hoshino T, Okamoto M, Kato S, Koda Y, Nagata N, Kinoshita M, Koga H, Yoon DY, Asao H, Ohmoto H, Koga T, Rikimaru T, Aizawa H

Multiple Authorship (Including Foreigners)

SARA and Hgs attenuate susceptibility to TGF-β1-mediated T-cell suppression., FASEB J., 2003

Kunzmann S, Wohlfahrt JG, Itoh S, Asao H, Komada M, Akdis CA, Blaser K, Schmidt-Weber CB

Multiple Authorship (Including Foreigners)

Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation., Biochem. Biophys. Res. Commun., 2003

Kanazawa C, Morita E, Yamada M, Ishii N, Miura S, Asao H, Yoshimori T, Sugamura K

Multiple Authorship (Only Japanese)

Identification of AMSH-LP containing a Jab1/MPN domain metalloenzyme motif., Biochem. Biophys. Res. Commun., 2003

Kikuchi K, Ishii N, Asao H, Sugamura K

Multiple Authorship (Only Japanese)

Human parvovirus B19 non-structural protein (NS1) induces cell cycle arrest at G1 phase., J. Virol., 2003

Morita E, Nakashima A, Asao H, Sato H, Sugamura K

Multiple Authorship (Only Japanese)

Ligand-Independent Degradation of Epidermal Growth Factor Receptor Involves Receptor Ubiquitylation and Hgs, an Adaptor Whose Ubiquitin-Interacting Motif Targets Ubiquitylation by Nedd4., Traffic, 2002

Katz M, Shtiegman K, Tal-Or P, Yakir L, Mosesson Y, Harari D, Machluf Y, Asao H, Jovin T, Sugamura K, Yarden Y

Multiple Authorship (Including Foreigners)

Signal transducing adaptor molecule STAM1 and STAM2 are required for T-cell development and survival., Mol. Cell. Biol., 2002

Yamada M, Ishii N, Asao H, Murata K, Kanazawa C, Sasaki H, Sugamura K

Multiple Authorship (Only Japanese)

The common g-chain is an indispensable subunit of the IL-21 receptor complex., Journal of Immunology, 167 1-5, 2001.04

Asao H, Okuyama C, Kumaki K, Ishii N, Tsuchiya S, Foster D, Sugamura K

Multiple Authorship (Including Foreigners)

Suppression of Thymic Development by the Dominant-negative Form of Gads., Int. Immunol., 2001

Kikuchi K, Kawasaki Y, Ishii N, Sasaki Y, Asao H, Takeshita T. Miyoshi I, Kasai N, Sugamura K

Multiple Authorship (Only Japanese)

Loss of Neurons in the Hippocampus and Cerebral Cortex of AMSH-Deficient Mice., Mol. Cell. Biol., 2001

Ishii N, Owada Y, Yamada M, Miura S, Murata K, Asao H, Kondo H, Sugamura K

Multiple Authorship (Only Japanese)

Promoting bone morphogenetic protein signaling through nagative regulation of inhibitory smads., EMBO J., 2001

Itoh F, Asao H, Sugamura K, Heldin CH, ten Dijke P, Itoh S

Multiple Authorship (Including Foreigners)

Human parvovirus B19 induces cell cycle arrest at G2 phase with accumulation of mitotic cyclines., J. Virol., 2001

Morita E, Tada K, Chisaka H, Asao H, Sato H, Yaegashi N, Sugamura K

Multiple Authorship (Only Japanese)

Interferon-gamma has dual potentials in inhibiting or promoting cell proliferation., Journal of Biological Chemistry, 275 867-874, 2000.01

Asao H, Fu X-Y

Multiple Authorship (Including Foreigners)

STAM2, a new member of the STAM family, binding to the Janus kinases., FEBS Letters, 2000

Endo K, Takeshita T, Kasai H, Sasaki Y, Tanaka N, Asao H, Kikuchi K, Yamada M, Chenb M, O'Shea JJ, Sugamura K

Multiple Authorship (Including Foreigners)

Hgs/Hrs, A FYVE domain protein is involved in Smad Signaling through cooperation with SARA., Mol. Cell. Biol., 2000

Miura S, Takeshita T, Asao H, Kimura Y, Murata K, Sasaki Y, Hanai J, Beppu H, Tsukazaki T, Wrana JL, Miyazono K, Sugamura K

Multiple Authorship (Including Foreigners)

Possible involvement of a novel STAM-associated molecule “AMSH” in intracellular signal transduction mediated by cytokines., J. Biol. Chem., 1999

Tanaka N, Kanako K, Asao H, Kasai H, Endo Y, Fujita T, Takeshita T, Sugamura K

Multiple Authorship (Only Japanese)

Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth., Journal of Biological Chemistry, 272 32785-32791, 1997.12

Asao, H., Sasaki, Y., Arita, T., Tanaka, N., Endo, K., Kasai, H., Takeshita, T., Endo, Y., Fujita, T., Sugamura, K

Multiple Authorship (Including Foreigners)

STAM, Signal transducing adaptor molecule, is associated with Janus Kinases and involved in signaling for cell growth and c-myc induction. , Immunity, 1997

Takeshita T, Arita T, Higuchi M, Asao H, Endo K, Kuroda H, Tanaka N, Murata K, Ishii N, Sugamura K

Multiple Authorship (Only Japanese)

Induction of IL-1β-converting enzyme-independent apoptosis by IL-2 in human T cell lines., Int. Immunol., 1997

Oda K, Asao H, Higuchi M, Tanaka N, Moffatt S, Nakamura M, Tabayashi K, Sugamura K

Multiple Authorship (Only Japanese)

Regulation of IL-2 signaling., Leukemia, 1997

Higuchi M, Asao H, Tanaka N, Oda K, Takeshita T, Sugamura K

Multiple Authorship (Only Japanese)

The interleukin 2 receptor γ chain: Its role in the multiple cytokine receptor complexes and T cell development in XSCID., Annu. Rev. Immunol., 1996

Sugamura K, Asao H, Kondo M, Tanaka N, Ishii N, Ohbo K, Nakamura M, Takeshita T

Multiple Authorship (Only Japanese)

Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM., Biochem. Biophys. Res. Commun., 1996

Takeshita T, Arita T, Asao H, Tanaka N, Higuchi M, Kuroda H, Kaneko K, Munakata H, Endo Y, Fujita T, Sugamura K

Multiple Authorship (Including Foreigners)

Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line., Eur. J. Immunol., 1996

Higuchi M, Asao H, Tanaka N, Oda K, Takeshita T, Nakamura M, Van Snick J, Sugamura K

Multiple Authorship (Including Foreigners)

Demonstration of a cross-talk between IL-2 and IL-5 in phosphorylation of IL-2 and IL-5 receptor β chains. , Int. Immunol., 1996

Ohbo K, Asao H, Kouro T, Nakamura M, Takaki S, Kikuchi Y, Hirokawa K, Tominaga A, Takatsu K, Sugamura K

Multiple Authorship (Only Japanese)

The common γ-chain for multiple cytokine receptors., Advances in Immunology, 1995

Sugamura K, Asao H, Kondo M, Tanaka N, Ishii N, Nakamura M and Takeshita T

Multiple Authorship (Only Japanese)

Impairment of ligand binding and growth signaling of mutant IL-2 receptor γ-chains in patients with X-linked severe combined immunodeficiency., J. Immunol., 1994

Ishii N, Asao H, Kimura Y, Takeshita T, Nakamura M, Tsuchiya S, Konno T, Maeda M, Uchiyama T, Sugamura K

Multiple Authorship (Only Japanese)

Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation. , FEBS Letters, 1994

Asao H, Tanaka N, Ishii N, Higuchi M, Takeshita T, Nakamura M, Shirasawa T and Sugamura K

Multiple Authorship (Only Japanese)

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor β and γ chains., Proc. Natl. Acad. Sci. USA, 1994

Tanaka N, Asao H, Ohbo K, Ishii N, Takeshita T, Nakamura M, Sasaki H, Sugamura K

Multiple Authorship (Only Japanese)

Reconstitution of the functional IL-2 receptor complexes on fibroblastoid cells: Involvement of the cytoplasmic domain of the γ chain in two distinct signaling pathways., Proc. Natl. Acad. Sci. USA, 1993

Asao H, Takeshita T, Ishii N, Kumaki S, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

A novel human tyrosine kinase gene inducible in T cells by interleukin 2., FEBS Letters, 1993

Tanaka N, Asao H, Ohtani K, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

Cloning of the mouse interleukin 2 receptor γ chain: Demonstration of functional differences between the mouse and human receptors., Biochem. Biophys. Res. Commun., 1993

Kumaki S, Kondo M, Takeshita T, Asao H, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

An associated molecule, p64, with IL-2 receptor b chain: its possible involvement in formation of the functional IL-2 receptor complex, Journal of Immunololy, 148 2154-2158, 1992.04

Takeshita T, Ohtani K, Asao H, Kumaki S, Nakamura M, Sugamura K

Multiple Authorship (Including Foreigners)

IL-2-dependent in vivo and in vitro tyrosine phosphorylation of IL-2 receptor g chain., FEBS Letters, 304 141-145, 1992.04

Asao H, Kumaki S, Takeshita T, Nakamura M, Sugamura K

Multiple Authorship (Including Foreigners)

An associated molecule, p64, with IL-2 receptor b chain: its possible involvement in formation of the functional IL-2 receptor complex, Journal of Immunololy, 148 2154-2158, 1992.04

Takeshita T, Ohtani K, Asao H, Kumaki S, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

Cloning of the g chain of the human IL-2 receptor, Science, 257 379-382, 1992.04

Takeshita T, Asao H, Ohtani K, Ishii N, Kumaki S, Tanaka N, Munakata H, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

IL-2-dependent in vivo and in vitro tyrosine phosphorylation of IL-2 receptor g chain., FEBS Letters, 304 141-145, 1992.04

Asao H, Kumaki S, Takeshita T, Nakamura M, Sugamura K

Multiple Authorship (Only Japanese)

Cell type-specific activation of a tyrosine kinase associated with IL-2 receptor β chain in response to IL-2., FEBS Letters, 1992

Kumaki S, Asao H, Takeshita T, Kurahayashi Y, Nakamura M, Beckers T, Engels JW, Sugamura K

Multiple Authorship (Including Foreigners)

Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75., Journal of Experimental Medicine, 171 637-644, 1990.04

Asao H, Takeshita T, Nagata K, Nakamura M, Sugamura K

Multiple Authorship (Including Foreigners)

The evidence for the IL-2 receptor b chain processing from p70 to p75, International Immunology, 2 470-472, 1990.04

Asao H, Takeshita T, Nakamura M, Nagata K, Sugamura K

Multiple Authorship (Only Japanese)

An associated molecule, p64, with high-affinity interleukin 2 receptor, International Immunology, 2 477-480, 1990.04

Takeshita T, Asao H, Suzuki J, Sugamura K

Multiple Authorship (Only Japanese)

Monoclonal antibody defining a molecule possibly identical to the p75 subunit of interleukin 2 receptor., Journal of Experimental Medicine, 169 1323-1332, 1989.04

Takeshita T, Goto Y, Tada K, Nagata K, Asao H, Sugamura K

Multiple Authorship (Including Foreigners)

Grant-in-Aid for Scientific Research(C)，2018.04 - 2021.03

Grant-in-Aid for Scientific Research(C)，2018.04 - 2020.03