Japan Pancreas Society

THE JAPANESE BIOCHEMICAL SOCIETY

In situ analysis of repair processes and responses for DNA damage in human cells. , 1998.10 -

DNA repair, single-strand break, poly(ADP-ribose)polymerase, XRCC1

Analysis of the relation between DNA damage responses and circadian rhythm, 1998.10 -

DNA repair, cell cycle checkpoint, clock gene, CRY

Analysis of the function for embryogenesis, expression and regulation of the nonspecific form of the 5-aminolevulinate synthase (ALAS-N), 2003.04 - 2008.12

heme, ALAS1, transcriptional regulation, mRNA instability

Analysis of unusual circadian locomotor activity and food anticipatory activity in mutant CRY1 transgenic mice, 2004.04 -

mutant cryptochrome1(CRY1), circadian clock, rhythm splitting, food-entrained circadian rhythm

Analysis of pathogenesis of novel diabetes mellitus shown by mutant CRY1 transgenic mice, 2008.04 -

mutant cryptochrome1(CRY1), diabetes mellitus, beta-cell dysfunction

Unusual circadian locomotor activity and pathophysiology in mutant CRY1 transgenic mice, Neuroscience Letters , 451(3) 246-251, 2009.01

岡野聡, 明石真, 早坂清, 中島修

Multiple Authorship (Only Japanese)

Indispensable function for embryogenesis, expression and regulation of the nonspecific form of the 5-aminolevulinate synthase gene in mouse, Genes to Cells, 15(1) 77-89, 2010.01

岡野聡, 周凌雲, 日下智聖, 柴田和秀, 清水和弘, 高旭, 菊池優子, 富樫義之, 細谷朋方, 高橋智 中島修, 山本雅之

Multiple Authorship (Including Foreigners)

Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells., Nucleic Acids Res, 33 422-429, 2005.01

岡野聡, 蘭利, Tomkinson AE, 安井明

Multiple Authorship (Including Foreigners)

In situ analysis of repair processes for oxidative DNA damage in mammalian cells., Proc Natl Acad Sci U S A, 101 13738-13743, 2004.09

蘭利, 中嶋敏, 大畑善嗣, 高尾雅, 岡野聡, 益谷美都子, Wilson SH, 安井明

Multiple Authorship (Including Foreigners)

Spatial and temporal cellular responses to single-strand breaks in human cells., Mol Cell Biol , 23 3974-3981, 2003.06

岡野聡, 蘭利, Caldecott K, 森俊雄, 安井明

Multiple Authorship (Including Foreigners)

Cellular responses and repair of single-strand breakes introduced by UV damage endonuclease in mammalian cells. , J Biol Chem, 275 32635-32641, 2000.10

岡野聡, 菅野新一郎, 安井明, 中嶋敏, 安井明

Multiple Authorship (Only Japanese)

A putative blue-light receptor from Drosophila melanogaster. , Photochem Photobiol , 69 108-113, 1999.01

岡野聡, 菅野新一郎, 高尾雅, Eker A P M, 塚原保夫, 安井明

Multiple Authorship (Including Foreigners)

Cloning of a novel ubiquitin-conjugating enzyme (E2) gene from the ciliate Paramecium tetraurelia., FEBS Lett, 319 1-4, 1996.08

岡野聡, 徳島秀幸, 中岡保夫, 清水喜久雄

Multiple Authorship (Only Japanese)

Effects of altered dynamics of zinc on cellular signaling, circadian clock, and loss of identity of mature β-cell, hokurikukan, Agricultural biotechnology – Physiological functions and practical applications of plant peptides – , 5(5) 99-102, 2021.04

Satoshi Okano

Response of clock genes and regulator of G protein signaling proteins to cellular stresses induced by altered dynamics of zinc in pancreatic β-cells, hokurikukan, Agricultural biotechnology – The new aspects of phospholipid metabolism – , 5(2) 88-92, 2021.01

Satoshi Okano

Clock Protein Cryptochrome and Zinc – Their interplay among circadian rhythms, pancreatic β-cells and precursor lesions of pancreatic ductal adenocarcinoma, hokurikukan, Agricultural biotechnology – Chrononutrition – , 4(8) 83-96, 2020.07

Satoshi Okano

Anomalous circadian rhythm and diabetes mellitus in mice induced by mutation of CRY1 protein at zinc-binding site: Relevance to the malignancy in human, and pancreatic ductal metaplasia, Agricultural biotechnology – Control of mineral element transport and human health – , 2(12) 69-79, 2018.11

Satoshi Okano

Unusual circadian rhythm, dysfunction of pancreatic ß-cell and generation of ductal metaplasia, hokurikukan, Bio Clinica -Obesity Disease Update- , 33(5) 453-462, 2018.05

Satoshi Okano

Unusual circadian rhythm and dysfunction and neogenesis of pancreatic β-cells in mutant cryptochrome1 transgenic mice , Hokurikukan, Bio Clinica − New development in antidiabetic drugs : Exploring the potential of SGLT2 Inhibitors − , 31(12) 90-99, 2016.10

Unusual circadian rhythm and β-cell dysfunction in mutant cryptochrome1 transgenic mice , Hokurikukan, Bio Clinica − Incretin; Resent topics − , 31(7) 79-87, 2016.06

Repair networks for base damage and single-strand breaks, Kyoritsu Shuppan , Protein, nucleic acid and enzyme , 46 959-967, 2001.06

Okano S, Yasui A

Grant-in-Aid for Scientific Research (B) [KAKENHI: 16790142]，2004.04 - 2006.03

(Grant No.8, 2019) Analyses of novel CRY1-binding proteins and the remodeling of pancreatic architecture in mutant CRY1 transgenic mice (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2019.04 - 2020.03, Collaboration in Japan

(Grant No.30, 2018) Analyses of novel CRY1-binding proteins and the remodeling of pancreatic architecture in mutant CRY1 transgenic mice (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2018.04 - 2019.03, Collaboration in Japan

(Grant No.7, 2017) Analyses of novel CRY1-binding proteins and the remodeling of pancreatic architecture in mutant CRY1 transgenic mice (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2017.04 - 2018.03, Collaboration in Japan

(Grant No.3, 2015) Elucidation of diabetes and rhythm disorder in mutant CRY1 transgenic mice using proteomics approach (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2016.04 - 2017.03, Collaboration in Japan

(Grant No.6, 2014) Elucidation of diabetes and rhythm disorder in mutant CRY1 transgenic mice using proteomics approach (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2014.04 - 2015.03, Collaboration in Japan

(Grant No.30, 2013) Elucidation of diabetes and rhythm disorder in mutant CRY1 transgenic mice using proteomics approach (the Joint Research Program of Joint Usage/Research Center at the Institute of Development, Aging and Cancer, Tohoku University), 2013.04 - 2014.03, Collaboration in Japan

The 4th International 3R Symposium, International presentation, 2003.11, Assembly of proteins and repair process at oxidative DNA damage in mammalian cells, Poster presentation

ASM meeting:Conference on DNA repair and Mutagenesis, International presentation, 2004.11, n situ and real time analysis of repair pathways for base damage and single-strand breaks in mammalian cells, Poster presentation

2nd World Congress of Chronobiology, International presentation, 2007.11, Poster presentation

The 36th Congress of the International Union of Physiological Sciences, International presentation, 2009.08, nusual circadian behavior and diabetes mellitus in mutant CRY1 transgenic mice, Poster presentation

6th ASRS, 34th JSSR,16th JSC, Joint Congress Osaka, Japan, International presentation, 2009.10, Food-entrained circadian rhythm in mutant CRY1 transgenic mice , Poster presentation

The 32th Annual Meeting of the Molecular Biology Society of Japan , Domestic presentation, 2009.12, Diabetes mellitus in mutant CRY1 transgenic mice (workshop: cancer, lifestyle-related disease and clock gene), Symposium, workshop panel (public)

Worldsleep 2011, International presentation, 2011.10, Unusual circadian rhythm and diabetes mellitus in mutant cryptochrome1 transgenic mice, Poster presentation

16th Japan-Korea Symposium on Diabetes Mellitus, International presentation, 2011.10, Diabetes mellitus in mutant cryptochrome1 transgenic mice at young and mature stages, Oral presentation (general)

9th IDF-WPR Congress / 4th AASD Scientific Meeting , International presentation, 2012.11, Features of diabetes mellitus in mutant cryptochrome1 transgenic mice at young stage, Oral presentation (general)

EBRS Congress 2013 , International presentation, 2013.08, Unusual food-entrained circadian rhythm and diabetes mellitus in mutant CRY1 transgenic mice, Poster presentation

Homeodynamics in Clocks, Sleep and Metabolism Tokyo Translational Therapeutics Meeting, International presentation, 2014.09, Regulation of Rgs4 in the islet of mutant cryptochrome1 transgenic mice, Poster presentation

The 37th Annual Meeting of the Molecular Biology Society of Japan, Domestic presentation, 2014.11, Senescence-like phenotype and dedifferentiation in pancreatic β-cells in diabetic mutant CRY1 transgenic mice, Poster presentation

75th Scientific Sessions American Diabetes Association (ADA), International presentation, 2015.06, Senescence-like phenotype in pancreatic ß-cells in diabetic mutant cryptochrome1 transgenic mice (e-poster: 2299-P), Poster presentation

EBRS Congress 2015, International presentation, 2015.08, Food-entrainable circadian rhythm and pathophisiology in Cys414-Ala mCRY1 transgenic mice, Poster presentation

Keystone Symposia Conference -Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies, International presentation, 2015.10, Unusual ductal structure in the islet of diabetic cysteine414-alanine mutant mCRY1 transgenic mice, Poster presentation

76th Scientific Sessions American Diabetes Association (ADA), International presentation, 2016.06, Anomalous ductal structure in the islet of diabetic cysteine414-alanine-mCRY1 transgenic mice (e-poster: 2073-P), Poster presentation

Tohoku Forum on Aging Science , International presentation, 2017.05, Poster presentation

77th Scientific Sessions American Diabetes Association (ADA), International presentation, 2017.06, Reduced expression of KPNA2 and dysfunction of β-cells in C414A-CRY1 transgenic mice (e-poster: 2184-P), Poster presentation

EBRS Congress 2017, International presentation, 2017.07 - 2017.08, Features of pancreatic intraepithelial neoplasia and tubular complex in diabetic cysteine414-alanine-mCRY1 transgenic mice, Poster presentation

78th Scientific Sessions American Diabetes Association (ADA), International presentation, 2018.06, Unusual duct-like cells in the islet of diabetic C414A-CRY1 transgenic mice (e-poster: 2127-P), Poster presentation

3rd Asian Forum on Chronobiology in 2018, International presentation, 2018.07, Mucin-producing duct-like cells in the islet of aged diabetic C414A-CRY1 mutant mice, Poster presentation

Sapporo Symposium on Biological Rhythm in 2018 , International presentation, 2018.07, Mucin-producing duct-like cells in the islet of aged diabetic C414A-CRY1 mutant mice, Poster presentation

IDF Congress 2019 in Busan, International presentation, 2019.12, Altered expression of karyopherin α2 and circadian clock genes in MIN6 cells mimicking hyperglycemia (e-poster: P-0359), Poster presentation

MBSJ2020 Online, Domestic presentation, 2020.12, Responses of transcription factor MTF1 and regulator of G protein signaling proteins to cellular stresses induced by altered dynamics of zinc in pancreatic β-cells, Other

81st Scientific Sessions American Diabetes Association (ADA), International presentation, 2021.06, Characteristic distribution of GRP78 in islets and intra-islet ductal cells of diabetic C414A-CRY1 transgenic mice (e-poster: 1245-P, 2021) , Poster presentation

83rd Scientific Sessions American Diabetes Association (ADA), International presentation, 2023.06, Overexpression of zinc-binding deficient Cryptochrome induces anomalous circadian rhythms, Transdifferentiation among pancreatic endocrine cells in diabetic mutant CRY1 transgenic mice , Poster presentation

The 26th International Association of Pancreatology (IAP), The 53rd Annual Meeting of Japan Pancreats Society (JPS), International presentation, 2022.07, Molecular circadian clock and β-cell dedifferentiation in MIN6 cells, Poster presentation

The 22nd Annual Meeting of the Japanese Society of Anti-Aging Medicine, Domestic presentation, 2022.06, Responses of RGS genes and Clock genes to induction of dedifferentiation in pancreatic β-cell line MIN6 cells , Poster presentation

82nd Scientific Sessions American Diabetes Association (ADA), International presentation, 2022.06, Possible delta to beta-cell transdifferentiation in aged diabetic mutant CRY1 transgenic mice (e-poster: 1453-P, 2022) , Poster presentation

The 51th Annual Meeting of Japan Pancreas Society, Domestic presentation, 2021.01, Analyses of intra-islet ducts in diabetic C414A-CRY1 transgenic mice, Other

80th Scientific Sessions American Diabetes Association (ADA) – Virtua, International presentation, 2020.06, Atypical trefoil factor family 2 expressing ß-cells of diabetic mutant CRY1 transgenic mice with intraislet ducts (e-poster: 2057-P, 2020), Poster presentation

79th Scientific Sessions American Diabetes Association (ADA), International presentation, 2019.06, Characteristic features in the intraislet ductal cells of diabetic C414A-CRY1 transgenic mice (e-poster: 328-LB, 2019) , Poster presentation